research Dupilumab: Friend or Foe to Alopecia Areata?
Dupilumab can help regrow hair in alopecia areata but stopping it may cause hair loss again.
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research Spherical Nucleic Acids as Emerging Topical Therapeutics: A Focus on Psoriasis
New topical treatment using spherical nucleic acids shows promise in reducing psoriasis inflammation.
research <p>Frontal Fibrosing Alopecia. An Example of Disrupted Aryl Hydrocarbon Receptor-Mediated Immunological Homeostasis in the Skin?</p>
Excessive sun protection might cause frontal fibrosing alopecia by disrupting skin immune balance.
research 5α-Reductase activity in the human hair follicle concentrates in the dermal papilla
The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.
research Alopecia areata: a review of disease pathogenesis
Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.
research Identifying key components and therapeutic targets of the immune system in hidradenitis suppurativa with an emphasis on neutrophils
The article suggests that targeting specific immune pathways could help control and treat the skin disease hidradenitis suppurativa.
research Melanocytes and Vitiligo (and Hair Graying)
Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.
research Updates In The Pathogenesis Of Alopecia Areata
Alopecia areata is an autoimmune condition causing hair loss, linked to genetic factors and immune system issues, with no cure yet.
research Hypothesis: Wound‐induced TLR 3 activation stimulates endogenous retinoic acid synthesis and signalling during regeneration
Activating TLR3 may help produce retinoic acid, important for tissue regeneration.
research Alopecia Areata
Understanding the immune-related causes of Alopecia Areata has led to potential treatments like JAK inhibitors.
research Newly Developed Targeted Therapies Against the Androgen Receptor in Triple-Negative Breast Cancer: A Review
Targeting androgen receptors shows promise for treating triple-negative breast cancer, but more research is needed.
research Pharmacology of anabolic steroids
Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.
research Novel mechanisms for the vitamin D receptor (VDR) in the skin and in skin cancer
Vitamin D receptor helps prevent skin cancer and supports skin health.
research Wound healing mechanism in Mongolian gerbil skin
Mongolian gerbils heal wounds differently than mice, with unique protein levels and gene expression that affect skin repair.
research Medical Management Options for Hair Loss
The document concluded that FDA-approved treatments like minoxidil and finasteride are effective for hair loss, while the effectiveness of natural remedies and other non-approved treatments is not well-supported by evidence.
research Effect of estrogens on skin aging and the potential role of SERMs
Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.
research The aetiopathogenesis of acne vulgaris - what's new?
Acne is caused by multiple factors including oil production, bacteria, inflammation, and possibly diet and environment.
research Toll-like receptor-targeted anti-tumor therapies: Advances and challenges
TLR-targeted therapies show promise in cancer treatment by helping destroy tumors.
research Through the lens of hair follicle neogenesis, a new focus on mechanisms of skin regeneration after wounding
Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.
research Harnessing neuroendocrine controls of keratin expression: A new therapeutic strategy for skin diseases?
Using neurohormones to control keratin can lead to new skin disease treatments.
research The Effect of Parathyroid Hormones on Hair Follicle Physiology: Implications for Treatment of Chemotherapy-Induced Alopecia
Parathyroid hormones are important for hair growth, but their use in treating hair loss from chemotherapy is still uncertain.
research Transcriptional Profiling in Rat Hair Follicles following Simulated Blast Insult: A New Diagnostic Tool for Traumatic Brain Injury
Hair follicles can help diagnose traumatic brain injury quickly and non-invasively.
research Identification of Biomarkers in Affected Hair Follicles from Chronic Discoid LupusErythematosus by Weighted Gene Co-Expression Network Analysis
Key genes linked to immune response are upregulated in hair follicles and skin tissues in chronic discoid lupus erythematosus.
research Identification of Biomarkers in Affected Hair Follicles from Chronic Discoid Lupus Erythematosus by Weighted Gene Co-Expression Network Analysis
Key genes linked to immune response are highly active in lupus-affected hair follicles.
research Vitamin D metabolism and function in the skin
Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.
research Probing the Effects of Stress Mediators on the Human Hair Follicle
Stress-related substance P may lead to hair loss and negatively affect hair growth.
research Successful Treatment of Alopecia Areata with Topical Calcipotriol
A boy with alopecia regrew hair using a vitamin D cream after other treatments failed.
research Prostaglandin E 2 Receptor 2 Modulates Macrophage Activity for Cardiac Repair
EP 2 receptor is essential for heart repair by helping macrophages work properly.
research Thymic Peptides Differentially Modulate Human Hair Follicle Growth
Some thymic peptides can increase human hair growth, while others may inhibit it.
research The Role of the Vitamin D Receptor in the Epidermal Stem Cell Response to Wounding
Vitamin D receptor is crucial for skin wound healing.