Search

for
Search:

GlossaryInterferons

Interferons are a group of signaling proteins produced by the immune system in response to viral infections and other stimuli. They play a crucial role in regulating immune responses and have been studied for their potential effects on hair biology, particularly in conditions like alopecia areata, where they may help modulate inflammation and promote hair regrowth. Key distinguishing characteristics of interferons include their ability to enhance the activity of immune cells and their role in inhibiting viral replication, which can indirectly influence hair follicle health and cycling.

Related Terms

Sort by

Research

30 / 1000+ results

Anti-TNF Antibody-Induced Psoriasiform Skin Lesions in Patients with Inflammatory Bowel Disease Are Characterised by Interferon-γ-Expressing Th1 Cells and IL-17A/IL-22-Expressing Th17 Cells and Respond to Anti-IL-12/IL-23 Antibody Treatment

research Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment

278 citations , March 2013 in “Gut”

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

research Interferon alfa-2a in the treatment of cutaneous T cell lymphoma

209 citations , March 1989 in “Journal of The American Academy of Dermatology”

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

research Interferon in the treatment of cutaneous T-cell lymphoma

107 citations , December 2003 in “Dermatologic Therapy”

Interferon, especially alfa interferon, is an effective treatment for cutaneous T-cell lymphoma with manageable side effects.

research Reversible Alopecia Universalis During Treatment with PEG-Interferon and Ribavirin for Chronic Hepatitis C

27 citations , April 2005 in “Journal of Chemotherapy”

Some patients may experience temporary total hair loss from hepatitis C treatment with PEG-interferon and ribavirin.

research INTERFERONS IN DERMATOLOGY

22 citations , April 1998 in “Dermatologic Clinics”

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

Segmental Vitiligo and Hair Curling After Interferon Alpha and Ribavirin Treatment for Hepatitis C

research Segmental Vitiligo and Hair Curling After Interferon α and Ribavirin Treatment for Hepatitis C

14 citations , January 2006 in “Skinmed”

A woman developed white patches on her skin and curly hair after hepatitis C treatment, likely due to the medication interferon alpha.

Partial Regrowth of Scalp Hair in a Patient Treated with Extracorporeal Photochemotherapy and Interferon α2a

research Partial regrowth of scalp hair in a patient treated with extracorporeal pholtochemotherapy and interferon ? 2a

2 citations , November 1998 in “Journal of The European Academy of Dermatology and Venereology”

A patient with a severe type of hair loss experienced partial hair regrowth after treatment with a specific light therapy and a medication called interferon α2a.

research Intrinsic Modulators of Hair Growth: Roles of Growth Factors, Cytokines, Chemokines, and Interferons

July 2025 in “International Journal of Trichology”

Biological factors are crucial for developing new hair restoration treatments.

Effect of Diode Pumping Solid State Laser with Wavelength 589 nm on Gene Expression of Interleukin-2 and Interferon-Gamma in Human T-Lymphocytes

research Effect of diode pumping solid state laser with wavelength 589 nm on gene expression of interlukine-2 and interferon-gamma Lowercase in human T-lymphocytes

September 2024 in “Journal of the Pakistan Medical Association”

A 589 nm laser increases IL-2 and IFN-y gene expression in human T-cells.

Skin Complications Associated With Interferon-Beta Treatment In Patients With Multiple Sclerosis, Tehran In 2021

research Skin Complications Associated with Interferon-β Treatment in Patients with Multiple Sclerosis, Tehran in 2021 - 2

July 2023 in “Journal of skin and stem cell”

Interferon beta treatment in MS patients can cause skin reactions and increased hair loss.

research The Role of Interferon-γ in Autoimmune Polyendocrine Syndrome Type 1

71 citations , May 2024 in “New England Journal of Medicine”

Ruxolitinib may effectively treat APS-1 by reducing harmful immune responses.

research A Review of Adverse Cutaneous Drug Reactions Resulting from the Use of Interferon and Ribavirin

64 citations , January 2009 in “Canadian Journal of Gastroenterology”

Interferon and ribavirin can cause serious skin reactions and other health issues.

research Concomitant Vitiligo and Psoriasis in a Patient Treated with Interferon Alfa‐2a for Chronic Hepatitis B Infection

60 citations , September 2004 in “Pediatric Dermatology”

A girl developed vitiligo and psoriasis after hepatitis B treatment, and stopping the treatment didn't help.

research Calcitonin gene‐related peptide (CGRP) may award relative protection from interferon‐γ‐induced collapse of human hair follicle immune privilege

47 citations , December 2011 in “Experimental Dermatology”

CGRP may help protect hair follicles from immune system attacks, potentially slowing hair loss.

Reversible Alopecia Universalis Secondary to PEG-Interferon Alpha-2b and Ribavirin Combination Therapy in a Patient with Chronic Hepatitis C Virus Infection

research Reversible alopecia universalis secondary to PEG-interferon ??-2b and ribavirin combination therapy in a patient with chronic hepatitis C virus infection

41 citations , August 2007 in “European Journal of Gastroenterology & Hepatology”

A woman's total hair loss from hepatitis C treatment grew back after stopping the medication.

research High dose interferon treatment in chronic hepatitis C.

36 citations , January 1993 in “Gut”

High-dose interferon is effective for chronic hepatitis C but often causes flu-like symptoms.

Lichen Planus and Other Cutaneous Manifestations in Chronic Hepatitis C: Pre- and Post-Interferon-Based Treatment Prevalence in a Cohort from a Low Hepatitis C Virus Endemic Area

research Lichen planus and other cutaneous manifestations in chronic hepatitis C: pre- and post-interferon-based treatment prevalence vary in a cohort of patients from low hepatitis C virus endemic area

34 citations , April 2008 in “Journal of the European Academy of Dermatology and Venereology”

Skin problems like itching, dry skin, and hair loss are more common in hepatitis C patients after interferon treatment, but lichen planus is not linked to the infection.

Tumor Necrosis Factor Alpha, Interferon Gamma, and Substance P Are Novel Modulators of Extrapituitary Prolactin Expression in Human Skin

research Tumour Necrosis Factor Alpha, Interferon Gamma and Substance P Are Novel Modulators of Extrapituitary Prolactin Expression in Human Skin

24 citations , April 2013 in “PLOS ONE”

TNFα, IFNγ, and Substance P significantly affect prolactin levels in human skin, suggesting new treatments for skin and hair conditions.

research Selective Expression of Chemokine Monokine Induced by Interferon-γ in Alopecia Areata

20 citations , September 2003 in “Journal of Investigative Dermatology”

Targeting MIG and MCP-1 may help treat inflammation in alopecia areata.

research Vogt-Koyanagi-Harada disease occurring during pegylated interferon-α2b and ribavirin combination therapy for chronic hepatitis C

17 citations , January 2011 in “The Korean Journal of Hepatology”

Vogt-Koyanagi-Harada disease can develop during interferon therapy for chronic hepatitis C.

research A randomized controlled clinical trial of recombinant interferon α‐2b in the treatment of acute post‐transfusion hepatitis C: A preliminary report

17 citations , January 1993 in “Journal of Gastroenterology and Hepatology”

Interferon α‐2b can temporarily reduce hepatitis C virus and normalize liver enzyme levels.

Treatment of Alopecia Areata with Anti-Interferon-Gamma Antibodies

research Treatment of Alopecia Areata with Anti-Interferon-γ Antibodies

16 citations , November 2005 in “Journal of Investigative Dermatology Symposium Proceedings”

Blocking interferon-gamma helps prevent and treat hair loss in Alopecia Areata.

research Interferon β Secreted from Human Hair Dermal Papilla Cells Inhibits the Growth of Outer Root Sheath Cells Cultured in Vitro

13 citations , January 2002 in “Biochemical and biophysical research communications”

Interferon β from hair cells stops the growth of other hair cells.

research Predictive factors for adverse dermatological events during pegylated/interferon alpha and ribavirin treatment for hepatitis C

11 citations , April 2014 in “Journal of Clinical Virology”

Older age, pre-existing skin conditions, cirrhosis, and pegylated interferon use increase the risk of skin issues during hepatitis C treatment.

Exacerbation of Alopecia Areata During Pegylated Interferon Alpha-2b and Ribavirin Therapy, Possibly Due to the Collapse of Hair Follicle Immune Privilege

research Exacerbation of alopecia areata during pegylated interferon alpha-2b and ribavirin therapy, possibly due to the collapse of hair follicle immune privilege

10 citations , September 2014 in “European Journal of Dermatology”

A woman's hair loss worsened after starting hepatitis C treatment due to immune changes in her hair follicles.

research Cutaneous ulcers due to interferon seem not to be related to the dosage

9 citations , September 1999 in “Journal of the European Academy of Dermatology and Venereology”

Skin ulcers from interferon may not depend on the amount given.

research Alopecia universalis as a side effect of pegylated interferon α-ribavirin combination therapy for hepatitis C: a rare case report

6 citations , October 2016 in “Journal of Chemotherapy”

A man lost all his hair as a rare side effect after hepatitis C treatment.