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The new gel with Zinc Oxide nanoparticles and finasteride shows promise for treating hair loss when applied to the skin.
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July 2021 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin” Rubbing skin increases absorption of water-soluble drugs from lotions and creams, but not oil-soluble drugs.
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February 2016 in “Journal of Microencapsulation” Improved finasteride formula allows slow, sustained release and better absorption for patients.
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January 2006 in “International Journal of Cosmetic Science” The study found that certain conditioning compounds can penetrate hair and potentially improve its resistance to damage.
July 2013 in “Pharmaceutical Regulatory Affairs Open Access” Invasomes with 0.5% limonene greatly improve skin delivery of finasteride.
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January 2010 in “Elsevier eBooks” Follicular Unit Hair Transplantation is a method for restoring hair by transplanting individual hair follicles.
January 2020 in “Korean journal of ophthalmology/Korean Journal of Ophthalmology” Minoxidil increases cell layer permeability by reducing tight junction proteins and raising ROS levels.
January 2020 in “Surgical and Cosmetic Dermatology” Hair loss in women with androgenetic alopecia was reduced by using a hair treatment with human hair follicle stem cells.
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May 2010 in “British Journal of Dermatology” Intermediate hair follicles are a better model for studying hair growth and testing hair loss treatments.
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January 2006 in “Drug development and industrial pharmacy” Adding TPGS to minoxidil solutions can improve skin penetration and retention, especially in water and PEG 400-based solutions.
October 2019 in “Skin appendage disorders” The vitreous membrane in hair follicles changes shape during the hair cycle and may affect hair growth and nutrient exchange.
July 2024 in “Journal of Investigative Dermatology” Human hair follicles have their own thyroid hormone system.
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July 2017 in “Journal of Drug Delivery Science and Technology” Scientists developed a new method to deliver alopecia treatment directly to hair follicles, which could be a promising treatment for hair loss and other hair diseases.
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August 2020 in “Polymers” The patch delivers more drugs through the skin effectively.
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December 1995 in “Archives of Dermatological Research” January 2022 in “OPAL (Open@LaTrobe) (La Trobe University)” Nanoparticles in sunscreen are generally safe as they stay on the skin's surface.
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August 2014 in “Archives of Pharmacal Research” Special nanoparticles increased skin absorption of hair loss treatments with fewer side effects.
August 2022 in “International journal of membrane science and technology” Finasteride diffuses spontaneously through SDS micelles, suggesting they can replace living cell membranes.
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November 2016 in “Nanoscale” Medium to larger nanogels effectively deliver drugs through hair follicles when heated.
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September 2019 in “British Journal of Dermatology” FOL-005 peptide can reduce human hair growth by lowering FGF7 levels.
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May 2021 in “Research Square (Research Square)” Ketoconazole loaded solid lipid nanoparticles can penetrate skin better than regular drug suspension and marketed product, providing slow, sustained release and improved stability.
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April 2023 in “Pharmaceuticals” The new delivery system improved hair growth in alopecia treatment.