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GlossaryInterleukin-1

protein that regulates immune and inflammatory responses

Interleukin-1 (IL-1) is a type of protein called a cytokine that plays a crucial role in the body's immune and inflammatory responses. It helps regulate immune reactions by promoting the activation of white blood cells and the production of other inflammatory molecules. Elevated levels of IL-1 are often associated with conditions like autoimmune diseases and chronic inflammation.

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research Effects of Acanthus ebracteatus Vahl. extract and verbascoside on human dermal papilla and murine macrophage

7 citations , January 2022 in “Scientific Reports”

Acanthus ebracteatus Vahl. extract and verbascoside may help prevent hair loss and promote hair growth due to their anti-inflammatory properties and ability to protect against cell death.

research Lactobacillus paracasei HY7015 and Lycopus lucidus Turcz. Extract Promotes Human Dermal Papilla Cell Cytoprotective Effect and Hair Regrowth Rate in C57BL/6 Mice

3 citations , November 2022 in “Molecules/Molecules online/Molecules annual”

The substances improved hair regrowth and protected hair cells in humans and mice.

research Deciphering the Skin Anti-Aging and Hair Growth Promoting Mechanisms of Opophytum forskahlii Seed Oil via Network Pharmacology

December 2025 in “International Journal of Molecular Sciences”

Opophytum forskahlii seed oil may help with anti-aging and hair growth.

Network Pharmacology and In Vivo Experimental Analysis for Validating the Antifibrotic Potential of Punica Granatum Leaves Against Skin Scleroderma: The Role of Oxidative Stress, Inflammation and TGF-β1/Snail 1/p-Smad 3 Signaling Pathway

research Network pharmacology and in vivo experimental analysis for validating the antifibrotic potential of Punica granatum leaves against skin scleroderma: the role of oxidative stress, inflammation and TGF-β1/Snail 1/p-Smad 3 signaling pathway

April 2026 in “Inflammopharmacology”

Inhibition of 5α-Reductase, IL-6 Secretion, and Oxidation Process of Equisetum Debile Extract as Functional Food and Nutraceutical Ingredients

research Inhibition of 5α-Reductase, IL-6 Secretion, and Oxidation Process of Equisetum debile Roxb. ex Vaucher Extract as Functional Food and Nutraceuticals Ingredients

49 citations , October 2017 in “Nutrients”

Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.

Ovarian Leukocyte Distribution and Cytokine/Chemokine mRNA Expression in Follicular Fluid Cells in Women with Polycystic Ovary Syndrome

research Ovarian leukocyte distribution and cytokine/chemokine mRNA expression in follicular fluid cells in women with polycystic ovary syndrome

69 citations , September 2006 in “Human Reproduction”

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

research Expression of NAD+dependent 15-hydroxyprostaglandin dehydrogenase and protection of prostaglandins in human hair follicle

11 citations , March 2008 in “Experimental Dermatology”

A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.

research Araliadiol Protects Human Keratinocytes From Oxidative Stress, DNA Damage, and Apoptosis via Activation of Antioxidant Signaling

January 2026 in “Frontiers in Bioscience-Landmark”

Araliadiol protects skin cells from damage by boosting antioxidant defenses.

research Functional Characterization of Callus Extracts of Apple 'Hirosaki' for Cosmetic Materials

August 2013 in “Han'gug saengmul gonghag hoeji/KSBB journal”

Apple 'Hirosaki' callus extracts may improve wrinkles, stimulate hair growth, and have anti-inflammatory effects for use in cosmetics.

research Human umbilical cord mesenchymal stem cell treatment alleviates symptoms in an atopic dermatitis-like mouse model

9 citations , May 2023 in “Stem Cell Research & Therapy”

Stem cell treatment from umbilical cords reduces symptoms of atopic dermatitis and may help hair growth.

research Meloside A Protects Dermal Papilla Cells from DHT-Induced Damage via Androgen Receptor Modulation

June 2025 in “Current Issues in Molecular Biology”

Meloside A may help protect hair cells from damage linked to hair loss.

research In Vitro Evaluation of the Effect of a Not Cross-Linked Hyaluronic Acid Hydrogel on Human Keratinocytes for Mesotherapy

5 citations , February 2021 in “Gels”

HYDRO DELUXE BIO hyaluronic acid hydrogel is compatible with skin cells, may reduce inflammation, promote blood vessel growth, and protect against oxidative stress, suggesting it could help revitalize hair follicles.

research Comprehensive Evaluation of Tectona grandis L.f.: Integrated In Vitro and In Silico Analysis of Steroid 5α-Reductase Inhibition and Anti-Inflammatory Properties

November 2025 in “ACS Omega”

Teak leaf extract may help hair growth and reduce inflammation safely.

Effect of Scenedesmus Deserticola JD052 Extracts on Hair Inductivity by Regulating the AKT and GSK3β/β-Catenin Signaling Pathways in Human Dermal Papilla Cells

research Effect of Scenedesmus deserticola JD052 Extracts on Hair Inductivity by Regulating the AKT and GSK3β/β-Catenin Signaling Pathways in Human Dermal Papilla Cells

February 2025 in “Applied Sciences”

Scenedesmus deserticola JD052 extracts may help hair growth and could be a natural treatment for hair loss.

research In vivo response of GsdmA3^Dfl/+ mice to topically applied fish oil – effects on cellular markers and macrophages

1 citations , June 2016 in “FEBS open bio”

Fish oil increased cell growth and macrophages in the skin but didn't affect COX-2 expression.

Cyanidin 3-O-Arabinoside Suppresses DHT-Induced Dermal Papilla Cell Senescence by Modulating p38-Dependent ER-Mitochondria Contacts

research Cyanidin 3-O-arabinoside suppresses DHT-induced dermal papilla cell senescence by modulating p38-dependent ER-mitochondria contacts

14 citations , March 2022 in “Journal of Biomedical Science”

Cyanidin 3-O-arabinoside may help treat a common form of hair loss by protecting cells against aging and improving cell function.

research Dormant tumor cells in ret transgenic mouse melanoma model and their interaction with memory T cells

January 2012 in “heiDOK (Heidelberg University)”

Dormant melanoma cells in mice interact minimally with memory T cells due to a suppressive tumor environment.

Retracted Article: Pumpkin Seeds (Cucurbita Pepo Subsp. Ovifera) Decoction Promotes Trichinella Spiralis Expulsion During Intestinal Phase Via 'Weep and Sweep' Mechanism

research RETRACTED ARTICLE: Pumpkin seeds (Cucurbita pepo subsp. ovifera) decoction promotes Trichinella spiralis expulsion during intestinal phase via “Weep and Sweep” mechanism

4 citations , January 2024 in “Scientific Reports”

Pumpkin seeds may help expel parasites, but findings are retracted.

Effects of Solvent System and Storage Condition on Chemical Stability of 5α-Reductase Inhibitor Compounds in Tectona Grandis Leaf Extracts

research Effects of Solvent System and Storage Condition on Chemical Stability of 5(alpha)-Reductase Inhibitor Compounds in Tectona grandis L.f. Leaf Extracts

February 2024 in “Trends in Sciences”

Store Tectona grandis leaf extracts in slightly acidic, light-protected conditions for best stability.

research OBESITY-RELATED FACTORS INVOLVED IN ENDOPLASMIC RETICULUM STRESS INDUCTION IN ADIPOCYTES

January 2015 in “Durham e-Theses (Durham University)”

Adipose tissue changes in obesity can trigger stress in fat cells.

research Procyanidin B-2, extracted from apples, promotes hair growth: a laboratory study

37 citations , January 2002 in “British journal of dermatology/British journal of dermatology, Supplement”

Apple extract called procyanidin B-2 was found to greatly increase hair growth.

K15 Promoter-Driven Enforced Expression of NKIRAS Exhibits Tumor Suppressive Activity Against the Development of DMBA/TPA-Induced Skin Tumors

research K15 promoter-driven enforced expression of NKIRAS exhibits tumor suppressive activity against the development of DMBA/TPA-induced skin tumors

4 citations , October 2021 in “Scientific Reports”

NKIRAS2 can suppress certain skin tumors but its effect on cancer varies with context and expression level.

Investigating the Mechanisms Underlying the Pathogenesis of Alopecia Areata

research Dermatologia e Procedimentos Estéticos Ed. XXVII

September 2025 in “Editora Pasteur eBooks”

Continuous learning and personalized treatments are crucial in dermatology due to rapid technological advancements.

Extracellular Vesicles Released by Hair Follicle and Adipose Mesenchymal Stromal Cells Induce Comparable Neuroprotective and Anti-Inflammatory Effects in Primary Neuronal and Microglial Cultures

research Extracellular vesicles released by hair follicle and adipose mesenchymal stromal cells induce comparable neuroprotective and anti-inflammatory effects in primary neuronal and microglial cultures

May 2023 in “Cytotherapy”

Hair follicle and adipose cell vesicles both protect neurons and reduce inflammation similarly.

research Pemphigus Vulgaris IgG and Methylprednisolone Exhibit Reciprocal Effects on Keratinocytes

99 citations , January 2004 in “Journal of Biological Chemistry”

Methylprednisolone helps skin cells stick together better in pemphigus vulgaris.

research Topical delivery of nanoemulsions for skin cancer treatment

34 citations , November 2023 in “Applied Materials Today”

Nanoemulsions can effectively treat skin cancer with fewer side effects.