759 citations
,
February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
156 citations
,
August 2016 in “Journal of controlled release” Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
131 citations
,
March 2004 in “The American journal of pathology” Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.
19 citations
,
May 2016 in “Aging Cell” Older people's sweat glands are less effective at helping skin wounds heal due to weaker cell connections.
15 citations
,
February 2015 in “Cell & tissue research/Cell and tissue research” P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.
10 citations
,
May 2018 in “Forensic Science International” Shrunken heads retain some facial features and hair characteristics, allowing for limited individual identification.
1 citations
,
January 2019 in “Elsevier eBooks” Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.
November 2025 in “Dermatology and Therapy” The drinkable supplement increased hair growth and was safe for women with hair loss.
October 2025 in “HAL (Le Centre pour la Communication Scientifique Directe)” Variegated coat color in cats is linked to the Silver locus.
Elastin-like recombinamers show promise for better wound healing and skin regeneration.
PlacMA hydrogels from human placenta are versatile and useful for cell culture and tissue engineering.
January 2020 in “Medical journal of clinical trials & case studies” A 37-year-old male with severe skin and internal issues has a rare inherited skin condition called dystrophic epidermolysis bullosa.
November 2019 in “Harper's Textbook of Pediatric Dermatology” The document is a detailed medical reference on skin and genetic disorders.
263 citations
,
February 2013 in “Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology” Polymeric nanoparticles show promise for treating skin diseases.
141 citations
,
August 2017 in “Developmental Dynamics” The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.
47 citations
,
March 2016 in “Journal of dermatology” Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.
53 citations
,
January 2017 in “Skin appendage disorders” Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.
27 citations
,
July 2017 in “Scientific Reports” N-WASP is essential for healthy skin and preventing inflammation.
23 citations
,
May 2020 in “Cell Death and Disease” Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.
7 citations
,
June 2024 in “Communications Medicine” Spaceflight can harm skin health by altering gene expression, affecting DNA, mitochondria, and skin barriers.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The mTurq2-Col4a1 mouse model shows that cells can divide while attached to stable basement membranes during development.
June 2023 in “International Journal for Research in Applied Science and Engineering Technology” Emulgel improves skin delivery of various drugs better than traditional methods.
January 2023 in “Pesquisa Veterinária Brasileira” A KRT71 mutation in Hereford cattle in Uruguay causes thin, curly hair and scaly skin.
January 2022 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” Uncombable hair syndrome causes frizzy hair and can affect the nervous system, eyes, and ears, often co-occurring with other hair, skin, nail, and teeth conditions, and is linked to three specific gene mutations.
85 citations
,
July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
72 citations
,
October 2009 in “The FASEB journal” TRH stimulates human hair growth and extends the hair growth phase.
44 citations
,
July 2011 in “Dermato-endocrinology” Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.
24 citations
,
July 2011 in “PubMed” Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.
16 citations
,
February 2019 in “Gene” Researchers found a good way to isolate hair follicle stem cells from newborn goats for further study.
14 citations
,
October 2018 in “PloS one” Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.