research Drug–Drug Coamorphous System of Tadalafil and Finasteride for Enhanced Pharmaceutical Performance
Combining tadalafil and finasteride improves their solubility and effectiveness.
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research Crystal Structure of 17-.BETA.-Benzoyloxy-16-.BETA.-methylpregna-4,6-diene-3,20-dione.
A new antiandrogen compound was made and its detailed three-dimensional shape was described.
research Is thyrotropin-releasing hormone a novel neuroendocrine modulator of keratin expression in human skin?
Thyrotropin-releasing hormone may help control skin and hair growth and could aid in treating related disorders.
research Structural optimization of pep7, a small peptide extracted from epimorphin, for effective induction of hair follicle anagen
Modified pep7, named EPM peptide, effectively promotes hair growth at low concentrations and works well with minoxidil.
research Structure of intermediate filament assembly in hair deduced from hydration studies using small-angle neutron scattering
Hair's internal fibers are arranged in a pattern that doesn't let much water in, and treatments like oils and heat change how much water hair can absorb.
research Hair surface interactions against different chemical functional groups as a function of environment and hair condition
Hydrophobic interactions affect virgin hair, while electrostatic interactions are key for bleached hair.
research Three-dimensional modelling of interchain sequence similarities and differences in the coiled-coil segments of keratin intermediate filament heterodimers highlight features important in assembly
Keratin heterodimers are preferred for their specific and structural advantages.
research Three strands ironed closely together
A new method was developed to create complex molecular knots using iron ions.
research Effect of disulfide bonds in human hair fibers on the melting behavior of their crystalline structure
Disulfide bonds affect the melting behavior of hair's crystalline structure, but hair retains some stability even after these bonds are broken.
research The effects of hydrophobic modifications on the interaction of human hair with water
Hydrophobic modifications make human hair less affected by water.
research Failure of intercellular adhesion in hair fibers with regard to hair condition and strain conditions
Hair breaks differently when wet or dry and is affected by its condition and treatments like perms and bleaching.
research Effect of Disulfide Bonds in Human Hair Fibers on the Melting Behavior of Their Crystalline Structure
Changing disulfide bonds in human hair affects its melting behavior and thermal stability.
research Structure and Mechanical Properties of Human Trichocyte Keratin Intermediate Filament Protein
Disulfide bonds make keratin in hair stronger and tougher.
research Interactions between Crossed Hair Fibers at the Nanoscale
Hair fibers interact through classical forces, which are influenced by treatments and products, important for hair care and other applications.
research Self-consistent field theory for the interactions between keratin intermediate filaments
Keratin filaments' elasticity is influenced by their terminal domains and surrounding medium.
research CRYSTAL STRUCTURE OF HSIANGHUALITE
research Probing androgen receptor co-factor selectivity profiles: a chemical tool to determine cross-talk between androgen receptor and β-catenin in vivo
PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.
research Molecular modeling of hair keratin/peptide complex: Using MM‐PBSA calculations to describe experimental binding results
Electrostatic interactions mainly stabilize the binding of peptides to hair keratin.
research N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting
Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.
research Suppression of fibroblast proliferation and lysyl hydroxylase activity by minoxidil.
Minoxidil slows fibroblast growth and collagen production, potentially treating keloids, hypertrophic scars, and connective tissue disorders.
research Synthesis and characterization of inclusion complex of the vasodilator drug minoxidil with β-cyclodextrin
Minoxidil mixed with β-cyclodextrin improves solubility and gradual release.
research Minoxidil specifically decreases the expression of lysine hydroxylase in cultured human skin fibroblasts
Minoxidil reduces lysine hydroxylase in skin cells.
research Effects of Minoxidil on Cultured Human Skin Fibroblasts
Minoxidil slows down skin cell growth and may help treat scars and skin conditions.
research Improving selective androgen receptor modulator discovery and preclinical evaluation
We need better ways to test and understand SARMs to make safer and more effective treatments.
research Valency based novel quantitative structure property relationship (QSPR) approach for predicting physical properties of polycyclic chemical compounds
The neighborhood face index (NFI) accurately predicts properties of complex molecules.
research Molecular elements of the regulatory control of keratin filament modulator AHF/trichohyalin in the hair follicle
The study concluded that a protein important for hair strength is regulated by certain molecular processes and is affected by growth phases.
research Assessment of retinol-binding protein 4 in patients with alopecia areata and androgenetic alopecia
Higher RBP4 levels found in people with two types of hair loss.
research A Hair Growth-Enhancing Component of Hydrolysate of Human Placenta: In vitro and In vivo Assessments
IGF-1 from human placenta helps hair grow.
research Tratamento da foliculite decalvante com laser de Erbium-YAG
Erbium-YAG laser treatment improved folliculitis decalvans without causing hair loss.
research Homogenization theory captures macroscopic flow discontinuities across Janus membranes
The homogenization theory effectively describes how flow behaves differently across asymmetric membranes.