101 citations
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July 1985 in “Journal of the American Academy of Dermatology” Biotin improved hair growth and combability in one child with uncombable hair syndrome.
June 1987 in “Pediatric Neurology Briefs” Biotinidase deficiency can cause symptoms like sleepiness, hair loss, and seizures.
3 citations
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January 1966 in “PubMed” 1 citations
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December 1965 in “PubMed” January 1999 in “Proceedings of the British Society of Animal Science” Biotin deficiency may harm hair follicle health and growth in Angora goats.
24 citations
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May 2017 in “PubMed” Biotin supplements for hair improvement are popular without scientific proof of effectiveness.
January 2025 in “Genetics in Medicine Open” Biotinidase deficiency can mimic neuromyelitis optica and should be considered for accurate diagnosis and treatment.
Biotin does not significantly help with hair growth.
5 citations
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March 2021 in “International Journal of Dermatology” Biotin supplementation during isotretinoin treatment for acne may help maintain skin hydration and improve hair growth.
January 1998 in “Proceedings of the British Society of Animal Science” Biotin supports cell growth and DNA synthesis in Angora goat hair follicles.
January 1998 in “Proceedings of the British Society of Animal Science” Biotin supports cell growth and DNA synthesis in Angora goat hair follicles.
22 citations
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September 2008 in “Brain & development” Biotin supplements increased biotin levels but did not significantly prevent hair loss in rats on valproic acid.
21 citations
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January 1945 in “Journal of Nutrition” Biotin deficiency in monkeys causes fur and skin issues, but 20 μg of biotin daily can prevent or cure it.
August 2018 in “Journal of the American Academy of Dermatology” Biotin treatment for hair, nail, and skin disorders has weak evidence and should not be recommended unless new research shows clear benefits.
4 citations
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August 2018 in “Journal of The American Academy of Dermatology” The authors agree that biotin may help certain hair disorders but lacks evidence for use in healthy people and call for more research.
August 2022 in “Journal of the American Academy of Dermatology” The authors agree they didn't discuss the risks of too much micronutrients and value the focus on biotin deficiency signs and treatment effectiveness.
August 2021 in “Benha Journal of Applied Sciences” Biotin supplements significantly improve hair loss in people with telegon effluvium who lack biotin.
Biotin supplements don't consistently help hair growth in alopecia unless there's a deficiency.
1 citations
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January 1999 in “Proceedings of the British Society of Animal Science” Biotin helps maintain hair follicle growth by affecting cell death and survival signals.
16 citations
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May 2009 in “Journal of child neurology” Valproic acid does not change biotinidase enzyme activity in children's blood.
September 2009 in “European journal of paediatric neurology” Biotin supplements did not significantly reduce hair loss in rats on valproic acid.
78 citations
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January 2017 in “Skin appendage disorders” Biotin supplements may improve hair and nail growth in people with certain deficiencies or conditions, but there's not enough evidence to recommend it for healthy individuals.
15 citations
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May 2006 in “Brain & development” Valproic acid may cause hair loss by reducing biotinidase enzyme activity in rats.
March 2023 in “JIIS (Jurnal Ilmiah Ibnu Sina): ilmu farmasi dan kesehatan” The best biotin hair tonic formula has 20% span 80, 9.47% tween 80, and 5% PEG 400.
40 citations
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January 2017 in “Intestinal Research” Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.
21 citations
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June 2011 in “Journal of child neurology” Valproic acid and carbamazepine do not change biotin or biotinidase levels but may lower zinc levels, still within normal range.
11 citations
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January 1989 in “PubMed” Biotin improved fur and skin conditions in most dogs.
May 2021 in “Zenodo (CERN European Organization for Nuclear Research)” Biotin may help hair and nails grow.
34 citations
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October 1975 in “Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis”
4 citations
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January 2011 in “Journal of Cosmetics, Dermatological Sciences and Applications” Vitamin B12 may promote hair growth by affecting certain cell processes.