research Reproductive System, Male
The document explains how sperm cells are produced, the role of testosterone in this process, and how toxins can reduce sperm count and fertility.
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research Curcumin derivatives inhibit testicular 17β-hydroxysteroid dehydrogenase 3
Curcumin and its derivatives can block an enzyme important for making testosterone, with one derivative being particularly strong.
research Behavioral and hormonal changes following the continuous administration of testosterone in females in capuchin monkey adult females (Sapajus Libidinosus)
Testosterone increases sexual behavior in female capuchin monkeys.
research Testicular Seminoma in a Transgender Woman: A Case Report
Transgender women can still get testicular cancer, so proper screening is important.
research Cellular actions of testosterone in vascular cells: Mechanism independent of aromatization to estradiol
Testosterone affects vascular cells directly without converting to estradiol.
research Pharmacokinetics of a transdermal testosterone cream in healthy postmenopausal women
A 5 mg dose of transdermal testosterone cream effectively restores testosterone levels in postmenopausal women.
research Sex-Chromosome-Related Dimorphism in Steroidogenic Enzymes and Androgen Receptor in Response to Testosterone Treatment: An In Vitro Study on Human Primary Skeletal Muscle Cells
Chromosomal differences affect how muscle cells respond to testosterone.
research Hormone-dependent medial preoptic/lumbar spinal cord/autonomic coordination supporting male sexual behaviors
Testosterone and its byproducts help support male sexual behavior through different pathways in the brain and body.
research Immunolocalization of androgen receptor in the epididymis of rats with dihydrotestosterone deficiency.
Finasteride changes androgen receptor location in rat epididymis without altering tissue structure.
research Serum Testosterone and Dihydrotestosterone and Incidence and Progression of Lower Urinary Tract Symptoms: Results From the REDUCE Study
Higher testosterone and DHT levels are not linked to urinary symptoms in men.
research Anabolic effects of testosterone are preserved during inhibition of 5α-reductase
Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.
research Testosterone therapy for transgender men
Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.
research SUN-195 Falsely Elevated Testosterone Levels: Role of LC-MS/MS in Reducing Unnecessary Testing
Using LC-MS/MS for hormone measurement can prevent false high testosterone results and avoid unnecessary tests.
research Nanomilled Oral Testosterone Plus Dutasteride Effectively Normalizes Serum Testosterone in Normal Men With Induced Hypogonadism
A combination of nanomilled oral testosterone and dutasteride normalized testosterone levels in men with low testosterone and is safe for short-term use.
research Cardiac and Medullary Neuroinflammatory Pathways Trigger Androgenic Incitement of Cardiovascular Sequels of Endotoxemia in Rats
Testosterone increases heart and blood pressure issues in rats with endotoxemia, and stopping testosterone production can reduce these problems.
research Testosterone and doping control
The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.
research Intralesional triamcinolone for flares of hidradenitis suppurativa (HS): A case series
Intralesional triamcinolone effectively reduces pain and inflammation in hidradenitis suppurativa flares.
research ESDR564 – Vertex and Occipital Intermediate and Terminal Hair Follicles from Androgenetic Alopecia Patients are Differentially Affected by Testosterone Ex Vivo
research Testosterone target therapy: focus on immune response, controversies and clinical implications in patients with COVID-19 infection
Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.
research Androgen binding to cytosol and nuclei of hamster sebaceous glands
Dihydrotestosterone specifically binds to hamster sebaceous glands, with a higher affinity than testosterone.
research Differential transcriptome study on the damage of testicular tissues caused by chronic infection of T. gondii in mice
Chronic T. gondii infection may harm male fertility.
research To study hypoactive sexual desire disorder in a fragile X carrier female successfully treated with local testosterone application
Local testosterone treatment improved sexual desire in a female with fragile X syndrome.
research Terazosin or baclofen in young men with chronic orchialgia: A cohort study of 499 patients
Both terazosin and baclofen effectively reduce pain in young men with chronic testicular pain, with no difference in their effectiveness.
research Actions of 5α-reductase inhibitors on the epididymis
5α-reductase inhibitors may reduce male fertility and could be used for male contraception.
research Investigation, treatment and monitoring of late‐onset hypogonadism in males: ISA, ISSAM, and EAU recommendations
Testosterone treatment for older men can have short-term benefits, but long-term risks are unclear, requiring careful evaluation and monitoring.
research Factors Driving Unique Urination Phenotypes of Male and Female 9-week-old C57BL/6J Mice
Testosterone significantly affects urination differences between male and female mice.
research The use of a transscrotal testosterone delivery system in the treatment of patients with weight loss related to human immunodeficiency virus infection
The transscrotal testosterone patch normalizes hormone levels in men with AIDS and weight loss but does not improve weight, body mass, or quality of life.
research Topical Testosterone Induces Acne Pilosebaceous Alterations on Rat Skin
Topical testosterone can cause acne-like skin changes.
research Androgenic modulation of arterial baroreceptor dysfunction and neuroinflammation in endotoxic male rats
Testosterone affects blood pressure control and inflammation in male rats with endotoxic shock, and blocking certain hormones may help treat it.
research Interaction between dermal papilla cells and follicular epithelial cells in vitro: effect of androgen
Testosterone increases hair follicle cell growth when beard or axillary skin cells are present together.