72 citations
,
November 2002 in “Journal of Investigative Dermatology” Estrogen receptor α controls hair growth cycles and skin thickness in male mice.
October 2023 in “Frontiers in endocrinology” Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.
1 citations
,
August 2012 in “Journal der Deutschen Dermatologischen Gesellschaft” A woman's hyperandrogenism was caused by a genetic mutation leading to non-classic adrenogenital syndrome.
55 citations
,
March 1990 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.
13 citations
,
October 2002 in “Journal of Biochemical and Biophysical Methods” Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.
15 citations
,
June 2020 in “Experimental Dermatology” Hormones and genes affect hair growth and male baldness.
May 2023 in “Frontiers in Endocrinology” Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.
January 2006 in “Benzina: Revista d'excepcions culturals” Trienones are more effective at inhibiting the enzyme linked to hair loss than dienones.
3 citations
,
February 2025 in “Endocrine” Confirm testosterone levels with advanced tests to avoid unnecessary procedures.
19 citations
,
March 1998 in “Endocrinology” Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.
20 citations
,
June 1995 in “Tetrahedron Letters” New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.
25 citations
,
March 2004 in “Regulatory Toxicology and Pharmacology” Using testosterone-stimulated weanling rats can effectively replace castrated rats for anti-androgen testing, reducing animal stress.
1 citations
,
October 2020 in “Current Drug Discovery Technologies” The research found that compound 6, a newly created steroid, is more effective at inhibiting 5α-reductase (an enzyme) than current treatments, suggesting it could be a better option for treating urinary tract symptoms in men.
10 citations
,
August 1991 in “PubMed” Inflammation, possibly triggered by a specific bacteria and activated by UV radiation, may contribute to male pattern baldness.
January 2004 in “Banca y finanzas: Revista profesional de gestión financiera” Androgens increase pigmentation in certain hamster skin areas, but estrogens can reverse this effect.
17 citations
,
January 2015 in “MedChemComm” New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.
June 2010 in “Journal of Chemical Crystallography” The compound was successfully made and shows potential for treating prostate cancer.
January 2004 in “Anticancer Research” Long-term antiandrogen use may increase aggressive prostate cancer risk.
4 citations
,
April 2002 in “Medical Hypotheses” Hormones cause hair loss by affecting cell growth and weakening cell attraction.
5 citations
,
December 2011 in “Drug Research” CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.
138 citations
,
April 2003 in “Carcinogenesis” 2-Methoxyestradiol causes cancer cell death by activating specific pathways, but androgens can block this effect.
September 2020 in “Current Enzyme Inhibition” Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.
29 citations
,
July 2009 in “BJU international” Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.
May 2012 in “Reactions Weekly” A man developed hair loss from testosterone treatment but improved with additional medication.
January 2024 in “Wiadomości Lekarskie” The ABI1 gene contributes to prostate cancer progression and treatment resistance.
4 citations
,
July 2020 in “Research Square (Research Square)” The research helps understand how finasteride works and aids drug development.
7 citations
,
October 2017 in “The Prostate” Baldness in men with prostate cancer is linked to higher levels of certain sex hormones, but chest hair density is not.
1 citations
,
May 2021 in “Problemy e̊ndokrinologii” Androgen levels can increase at any age, affecting symptoms like acne, hair loss, and prostate size.
1 citations
,
March 2012 in “Journal of Dermatological Science” Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.
15 citations
,
June 1986 in “Pediatric Dermatology” Androgens increase pigmentation in young hamsters, but estrogens can reverse this effect.