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Grouping certain skin cells together activates a growth pathway that helps create new hair follicles.

Finasteride causes abnormal growth in male mice cells at high doses.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.

Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.

Birth control pills increase certain receptor activities in female gerbil prostate glands and can lead to prostate changes.

Protein extract from embryonic skin can create new hair follicles in adult life, primarily through effects on fibroblasts.

The discovery of 5α-reductase deficiency in guevedoces led to the development of important urologic medications.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

Certain genes and X chromosome patterns may significantly contribute to the development of hair loss.

Estrogen receptor α controls hair growth cycles and skin thickness in male mice.

Finasteride use may be linked to rare testicular tumor, but more research needed.

Androgens increase pigmentation in certain hamster skin areas, but estrogens can reverse this effect.

Blocking androgens in male rats increased estrogen and made them more active.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Estrogen affects hair growth and skin cell multiplication.