September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.
10 citations
,
October 2012 in “Andrology” Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.
100 citations
,
July 2004 in “The Journal of Sexual Medicine” Hormones like estrogen, testosterone, progesterone, and prolactin play complex roles in female sexual function, with testosterone potentially improving sexual desire, arousal, and satisfaction. However, more research is needed to establish safe and effective hormone treatments for female sexual dysfunction.
December 2025 in “Scientific Reports” Gut microbiota and metabolic pathways may play a key role in PCOS development.
21 citations
,
February 2003 in “Hormones and Behavior” Androgens boost certain nest-building behaviors and greatly reduce food intake in rabbits.
December 2025 in “Pakistan Journal of Health Sciences” Estrogen deficiency in postmenopausal women can cause skin and hair issues, but local estrogen therapies help improve vaginal health.
19 citations
,
October 2017 in “The FASEB Journal” Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.
May 2021 in “International journal of developmental research” Estrogens and progesterone are key in regulating melasma pigmentation.
October 2023 in “Apollo medicine” The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.
71 citations
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February 2000 in “Endocrinology and metabolism/American journal of physiology: endocrinology and metabolism” Estradiol stops hair growth in mice, but an antagonist can reverse this effect.
April 2019 in “Journal of the Endocrine Society” A woman's severe male-like symptoms were caused by a rare, benign tumor in her ovary that produced male hormones.
34 citations
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October 1975 in “Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis”
13 citations
,
July 2018 in “General and comparative endocrinology” Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.
October 2023 in “Journal of the Endocrine Society” A woman's ovarian fibroma caused high testosterone levels, which normalized after surgery.
14 citations
,
December 2013 in “Experimental Dermatology” The T-zone on the face has more androgen receptors and produces more oil than the U-zone.
41 citations
,
November 2003 in “Annals of the New York Academy of Sciences” Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.
17 citations
,
July 2013 in “Amino Acids” Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.
150 citations
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June 1999 in “Oncogene”
May 2021 in “Journal of the Endocrine Society” A woman's severe hormone imbalance after menopause led to finding a rare ovarian tumor, treated by surgery.
17 citations
,
February 2003 in “Australasian Journal of Dermatology” Hair loss in postmenopausal woman caused by ovarian issue.
9 citations
,
November 2012 in “Biomolecules & therapeutics” A compound from brown algae boosts the production of a certain inflammatory substance in skin cells.
7 citations
,
February 2025 in “Stem Cell Research & Therapy” Human hair follicle stem cells improve ovarian function in mice with damaged ovaries.
October 2022 in “Journal of the ASEAN Federation of Endocrine Societies” GnRH-a or orchiectomy is more effective than anti-androgens for managing hormone levels in transgender women.
April 2020 in “Journal of the Endocrine Society” A woman's high testosterone and related symptoms were caused by overactive cells in her ovaries.
69 citations
,
September 2006 in “Human Reproduction” Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.
January 2014 in “edoc (University of Basel)” Anabolic steroids and inflammation can disrupt androgen metabolism, potentially causing health issues.
July 2024 in “Journal of the ASEAN Federation of Endocrine Societies” In post-menopausal women, signs of increased male hormones should be checked for possible ovarian cancer.
November 2022 in “Journal of the Endocrine Society” Removing the ovarian tumor improved the woman's hormonal symptoms.
83 citations
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July 2004 in “Pharmacology Biochemistry and Behavior” Higher 3α,5α-THP levels in the brain may reduce depression in pregnant rats.
151 citations
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December 2004 in “Neuropharmacology” Progesterone reduces anxiety without needing progesterone receptors.