38 citations
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May 1971 in “Clinical genetics” A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.
Hirsutism is excessive male-pattern hair growth in women, often treated cosmetically or with hormone therapy if contraception is also desired.
August 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Normal cells outcompete and remove mutant cells in the pancreas with the help of the EphA2 receptor.
7 citations
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February 1962 in “Experimental Biology and Medicine” Male and female mice have different lipid compositions in their skin during hair growth cycles.
October 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Intralesional corticosteroids work better than topical ones for hair regrowth in alopecia areata.
January 2019 in “Publisher” Human basal cell carcinomas and squamous cell carcinomas have unique gene expression patterns not fully mirrored in mouse models.
9 citations
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February 2016 in “Cambridge University Press eBooks” The conclusion is that self-concept, shame, and emotion regulation are key factors in hoarding disorder, body dysmorphic disorder, and trichotillomania, and should be targeted in treatment and research.
1 citations
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January 2009 in “Journal of Clinical Dermatology” More men have Androgenic Alopecia than women, it's often inherited, and stress can contribute to it.
46 citations
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October 2012 in “Seminars in reproductive medicine” Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.
83 citations
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September 1993 in “Endocrinology and Metabolism Clinics of North America”
January 2024 in “Zenodo (CERN European Organization for Nuclear Research)” The conclusion is that certain traits, including perceived facial aging and BMI, are linked to perceived youthfulness differently in men and women.
3 citations
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February 2017 in “Archives of Medical Science” Finasteride treatment changes Cx43 in rat testes, possibly causing fertility issues.
28 citations
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March 2010 in “British Journal of Dermatology” Genetic marker rs12558842 strongly linked to male hair loss.
January 2005 in “Journal of Cutaneous Pathology” A unique type of complex cyst was found on a man's scrotum.
21 citations
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January 2020 in “General and Comparative Endocrinology” Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
April 2016 in “Journal of The American Academy of Dermatology” Women with PCOS often have hirsutism and skin changes, which indicate a need for metabolic health checks.
13 citations
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September 1986 in “Archives of Dermatology” Women with more 3α,17β-androstanediol glucuronide compared to sex hormone binding globulin are more likely to have female pattern baldness.
4 citations
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January 2000 in “PubMed” Early balding in men might be a male hormonal equivalent of polycystic ovaries syndrome in women.
October 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Six new genes linked to early hair loss were found, which also surprisingly connect to Parkinson's disease and lower fertility.
21 citations
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April 2016 in “Journal of Dermatological Treatment” Finasteride may cause mental and sexual side effects, with hand preference and sexual orientation possibly affecting severity.
11 citations
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October 2020 in “General and comparative endocrinology” Male C57BL/6 mice show age-related fluctuations in certain hormones and their ratios in both blood and hair.
June 2024 in “Skin Health and Disease” Men with alopecia often feel less confident and have lower wellbeing, needing more support.
December 2024 in “Dermatologic Surgery” January 2026 in “Journal of International Crisis and Risk Communication Research” Young adults need better education and healthcare access for PCOS and IIH.
January 2010 in “The Chinese Journal of Dermatovenereology” Androgenetic alopecia is more common in Chinese Han than in Chinese Yi in Liangshan.
1 citations
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April 2022 in “Indian Journal of Plastic Surgery” India is seeing more cases of gender incongruence and changes in how it's understood and managed legally and medically.
5 citations
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March 1981 in “PubMed” A girl grew extra hair in areas where she had insect bites.
Deleting the MAD2L1 gene in mice led to rapid tumor growth despite chromosomal instability.
31 citations
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September 2020 in “Clinical endocrinology” Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.
33 citations
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April 2020 in “Journal of Clinical Investigation” Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.