November 2001 in “Oncology Times” The committee decided not to approve the drug due to low effectiveness and high risks.
August 2020 in “Bioscience Biotechnology Research Communications” Topical anaesthesia reduces injection pain better than a vibrating device.
Different botulinum toxin products and concentrations can effectively reduce sweating, itching, bladder pressure, hair loss, and muscle spasms.
1 citations
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February 2021 Ice packs and vibration devices can reduce pain during scalp injections.
1 citations
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September 2021 in “Dermatologic Therapy” Botulinum toxin injections effectively relieve pain from cutaneous leiomyomas.
Intralesional triamcinolone acetonide is preferred for treating patchy alopecia areata due to fewer side effects.
August 2018 in “Dermatologic Surgery” September 2022 in “International Journal of Trichology” Both microneedling and injections are equally effective for treating alopecia areata.
July 2023 in “International journal of dermatology, venereology and leprosy sciences” Intradermal injections might work better for common hair loss than other treatments.
4 citations
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May 2019 in “Journal of Cosmetic Dermatology” Using a smaller syringe causes less pain when giving an injection.
January 2023 in “Л.Н. Гумилев атындағы Еуразия ұлттық университетінің хабаршысы” Botulinum toxin is effectively used to treat various painful conditions and its therapeutic uses are growing.
99 citations
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August 1998 in “Pain” Blocking GABA(A) receptors increases neuron sensitivity, showing GABA and glycine have different roles in pain.
TCA injections are more effective and safer than cryotherapy for treating alopecia areata.
July 2005 in “CME: Your SA Journal of CPD” Botulinum toxin is a safe alternative for treating migraines without common side effects, but should be used after other treatments fail.
2 citations
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November 2024 in “Aesthetic Surgery Journal” Vibration anesthesia effectively and safely reduces pain during botulinum toxin injections.
September 2022 in “Journal of Ayub Medical College Abbottabad” Steroid injections are more effective than platelet rich plasma for treating patchy hair loss.
19 citations
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October 2013 in “Headache: The Journal of Head and Face Pain” The document concludes that inhalation of oxygen and sumatriptan injections are primary for cluster headaches, indomethacin for paroxysmal hemicrania, and lidocaine and lamotrigine for SUNCT, but SUNCT often resists treatment.
9 citations
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March 2024 in “Journal of Biomaterials Applications” Rizatriptan benzoate-loaded dissolving microneedles are effective and convenient for treating acute migraines.
May 2018 in “Journal of Sun Yat-sen University” 100 citations
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July 2006 in “British Journal of Dermatology” Triamcinolone acetonide injections help hair regrow quickly in mild alopecia but not in severe cases.
1 citations
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August 2021 in “Journal of The American Academy of Dermatology” Ice cooling and vibration can reduce pain during PRP scalp injections without affecting treatment effectiveness.
September 2025 in “The health sciences AUS.” Intralesional triamcinolone acetonide effectively treats acne keloidalis nuchae with minimal side effects.
2 citations
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November 1996 in “Transplantation” Injecting recipient splenocytes into donors' thymus can prevent graft-versus-host disease.
October 2020 in “International Journal of Medical Arts (Print)” The PEEK cage reduced pain more than the dynamic cervical implant, but the implant allowed slightly better movement after surgery.
Injecting patients' own PRP into their thyroid improved thyroid function and symptoms in most hypothyroidism cases.
11 citations
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January 2020 in “Journal of Drugs in Dermatology” Intralesional triamcinolone acetonide is effective and safe for treating early to mid-stage traction alopecia.
14 citations
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January 2024 in “Theranostics” Intranasal delivery of gene therapy shows promise for treating ischemic stroke.
April 2023 in “Journal of Investigative Dermatology” Injecting anti-herpes antibodies locally can prevent skin lesions and sweating problems caused by herpes simplex virus in mice.
1 citations
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July 2023 in “Pharmaceutics” New microneedles deliver drugs through the skin accurately and effectively.
Adding a zygomaticotemporal nerve block reduces pain more effectively during hair regrowth treatments.