October 2024 in “The Journal of Dermatology” Intravenous corticosteroid therapy is effective for long-term hair regrowth in alopecia areata, and a scoring system helps predict treatment success and relapse.
October 2021 in “Dermatology practical & conceptual” High-dose corticosteroids can significantly regrow hair in severe alopecia areata.
8 citations
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July 2018 in “The Journal of Dermatology” Current corticosteroid pulse therapy is not very effective for severe rapidly progressive alopecia areata.
39 citations
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January 2012 in “Dermatology” Combining high-dose corticosteroids with methotrexate may be effective and safe for severe alopecia areata.
38 citations
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January 2013 in “Dermatology” Careful patient selection is key for effective pulse corticosteroid treatment in children with alopecia areata.
July 2026 in “Scholars Journal of Medical Case Reports” This case report discusses a 37-year-old woman with the rare coexistence of alopecia areata, lichen planopilaris, and lichen planus pigmentosus. The patient experienced diffuse non-scarring alopecia, scar-like patches, and loss of body hair. Trichoscopy and biopsies revealed distinct characteristics of each condition, such as follicular miniaturization and interface folliculitis. Treatment with monthly intravenous corticosteroid pulses and weekly methotrexate stabilized the condition and led to slight regrowth of scalp and eyebrow hair after one year, although pigmentation changes persisted. The report highlights the importance of examining different scalp zones separately and targeting active areas for biopsy, as scarring and non-scarring alopecias may coexist and require different treatment approaches.
2 citations
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June 2025 in “Journal of Investigative Dermatology” CD8+ T cells re-expressing CD45RA may predict treatment resistance in severe alopecia areata.
April 2023 in “Journal of Investigative Dermatology” Increased TEMRA cells can predict treatment outcomes in rapidly progressive alopecia areata.
15 citations
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May 2017 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” High-dose corticosteroids and methotrexate had a modest effect on severe childhood alopecia, but side effects and relapse were concerns.
October 2023 in “Dermatology practical & conceptual” Pulse corticosteroids help regrow hair in alopecia areata but have side effects, especially betamethasone.
1 citations
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October 2010 in “Faṣlnāmah-i bīmārīhā-yi pūst” Methotrexate with corticosteroids can help regrow hair in severe alopecia areata but may cause relapses and side effects.
14 citations
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January 2015 in “Indian journal of dermatology, venereology, and leprology” Methylprednisolone infusions can help some people with severe alopecia regrow hair.
December 2025 in “Cosmoderma” Systemic corticosteroids help manage vitiligo by slowing progression and aiding repigmentation.
July 2013 in “Our Dermatology Online” Oral methylprednisolone pulse therapy helped an 11-year-old regrow 80% of his hair in six months.
1 citations
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February 2024 in “JEADV Clinical Practice” Pulse corticosteroid therapy helps many with severe alopecia areata regrow hair, but has side effects.
December 2011 in “InTech eBooks” Systemic corticosteroids can help treat rapidly spreading vitiligo but require more research for safer use.
31 citations
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April 2016 in “Journal of the American Academy of Dermatology” Oral dexamethasone may help regrow hair in adults with alopecia totalis and universalis.
14 citations
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January 2015 in “Annals of dermatology/Annals of Dermatology” Corticosteroid pulse therapy is more effective for severe alopecia areata than combination therapy.
5 citations
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August 1998 in “PubMed” Intravenous cyclophosphamide effectively treated steroid-resistant lupus cystitis and peritonitis.
20 citations
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October 2003 in “The Journal of Dermatology” DCP therapy causes side effects like weakness, flushing, headaches, and taste changes, but less frequently causes hypertension and diabetes.
19 citations
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January 2013 in “Annals of Dermatology” Early high-dose steroid treatment helps prolong disease-free periods in severe alopecia areata.
10 citations
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July 2019 in “Indian Journal of Dermatology” Weekly azathioprine pulse is a better alternative to corticosteroids for treating alopecia areata due to fewer side effects.
2 citations
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January 2018 in “International journal of research in dermatology” Intralesional corticosteroids are the best for limited alopecia areata, oral steroids are less effective, and PRP is safe and promising, especially for children and severe cases.
50 citations
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January 2016 in “Journal of the American Academy of Dermatology” Pulse steroid therapy for alopecia areata shows a 43% complete response rate but has a high relapse rate, especially in children.
41 citations
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September 2018 in “Australasian journal of dermatology” No systemic treatment for alopecia areata has strong evidence of effectiveness.
4 citations
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January 2025 in “Dermatologica Sinica” Experts recommend personalized treatment plans for alopecia areata, using corticosteroids and minoxidil for mild cases, and stronger medications for severe cases.
21 citations
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May 2017 in “Paediatric drugs” Individualized treatment plans are crucial for children with alopecia areata, with promising options like JAK inhibitors showing significant hair regrowth.
5 citations
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July 2020 in “Recent patents on inflammation & allergy drug discovery” Childhood Alopecia Areata causes hair loss and requires varied treatments, with psychological support being crucial.
33 citations
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October 2018 in “BMJ Case Reports” Aggressive treatment in young patients with certain drug reactions may lead to multiple autoimmune diseases later.
18 citations
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January 2017 in “Journal der Deutschen Dermatologischen Gesellschaft” High and low doses of prednisolone helped 62% of children with severe alopecia regrow hair with some weight gain and mild acne as side effects.