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research Topical Cyperus rotundus essential oil for treatment of axillary hyperpigmentation: a randomized, double‐blind, active‐ and placebo‐controlled study

2 citations , October 2021 in “Clinical and experimental dermatology”

Cyperus rotundus essential oil effectively treats underarm darkening, reduces inflammation, and slows hair growth.

Development of Novel Indole-Based Bifunctional Aldose Reductase Inhibitors and Antioxidants as Promising Drugs for the Treatment of Diabetic Complications

research Development of Novel Indole-Based Bifunctional Aldose Reductase Inhibitors/Antioxidants as Promising Drugs for the Treatment of Diabetic Complications

9 citations , May 2021 in “Molecules”

New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.

research Single‐cell transcriptomics reveals a senescence‐associated IL ‐6/ CCR6 axis driving radiodermatitis

9 citations , July 2022 in “EMBO molecular medicine”

Blocking certain immune signals can reduce skin damage from radiation therapy.

research Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism

July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Synthesis of Spiro[cyclohexane-1,2'-[2H]indene] Derivatives as Inhibitors of Steroid 5α-Reductase

research Synthesis of Spiro[cyclohexane-1,2?-[2H]indene] derivatives as inhibitors of steroid 5?-reductase

8 citations , June 1995 in “Helvetica Chimica Acta”

Compound 15a was effective in inhibiting 5α-reductase.

Novel Lead Generation Through Hypothetical Pharmacophore Three-Dimensional Database Searching: Discovery of Isoflavonoids as Nonsteroidal Inhibitors of Rat 5α-Reductase

research Novel Lead Generation through Hypothetical Pharmacophore Three-Dimensional Database Searching: Discovery of Isoflavonoids as Nonsteroidal Inhibitors of Rat 5α-Reductase

27 citations , October 2001 in “Journal of Medicinal Chemistry”

Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.

research CC-type glutaredoxins mediate plant response and signaling under nitrate starvation in Arabidopsis

36 citations , November 2018 in “BMC plant biology”

ROXY proteins help plants respond to nitrate shortage by affecting nutrient sensing and growth.

research Icariin promotes mouse hair follicle growth by increasing insulin-like growth factor 1 expression in dermal papillary cells

22 citations , February 2017 in “Clinical and Experimental Dermatology”

Icariin helps mouse hair grow by boosting a growth factor in skin cells.

research The extract of Cyperus rotundus rhizome promotes hair growth and modulates hair cycle in vivo and in vitro

February 2026 in “Chinese Journal of Natural Medicines”

research Synthesis and biological activity evaluation of new isatin-gallate hybrids as antioxidant and anticancer agents (in vitro) and in silico study as anticancer agents and coronavirus inhibitors

3 citations , June 2024 in “Pharmacia”

New isatin-gallate hybrids show promise as antioxidants, cancer treatments, and coronavirus inhibitors.

research Circulating and/or cutaneous irisin resistance: A novel link among androgenetic alopecia, comorbid metabolic syndrome and cardiovascular risks

May 2023 in “Journal of Cosmetic Dermatology”

Androgenetic alopecia is linked to higher cardiovascular and metabolic risks, possibly due to irisin resistance.

research A simple method for the demonstration of the iron pigment in human red hair.

June 1947 in “PubMed”

research A novel calmodulin‐interacting Domain of Unknown Function 506 protein represses root hair elongation in Arabidopsis

14 citations , March 2022 in “Plant Cell & Environment”

The protein AtRXR3 limits root hair growth in Arabidopsis, affecting phosphorus uptake.

research PHYTOCHEMICAL INVESTIGATIONS OF THE LEAVES AND FLOWERS OF HIBISCUS ROSA-SINENSIS L.

4 citations , October 2017 in “Indian drugs”

Hibiscus rosa-sinensis L. leaves and flowers contain various compounds with potential medicinal uses.

[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs

research [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs

26 citations , July 2007 in “Biochemical Pharmacology”

ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.

Natural Product-Inspired Bis(Trifluoromethyl) Phenyl Hydroxycinnamate Derivatives as Promising Nonsteroidal Inhibitors of Human Steroid 5α-Reductase Type-1: Synthesis, In Vitro, and In Silico Studies

research Natural Product-Inspired Bis(trifluoromethyl) Phenyl Hydroxycinnamate Derivatives as Promising Nonsteroidal Inhibitors of Human Steroid 5α-Reductase Type-1: Synthesis, In Vitro, and In Silico Studies

August 2025 in “ACS Omega”

New compounds show promise as nonsteroidal treatments for hair loss.

research β-sitosterol in Yijing Hugui decoction prevents cyclophosphamide-induced premature ovarian insufficiency via the AKT1/Nrf2 pathway

7 citations , March 2025 in “Cytotechnology”

research CRYSTAL STRUCTURE OF HSIANGHUALITE

8 citations , January 1991 in “Soviet physics. Doklady”

Phytochemical, Chemotaxonomic and Bioinformatics Study on Laportea Bulbifera (Urticaceae)

research ERULUS Is a Plasma Membrane-Localized Receptor-Like Kinase That Specifies Root Hair Growth by Maintaining Tip-Focused Cytoplasmic Calcium Oscillations

32 citations , May 2018 in “The Plant Cell”

ERULUS is crucial for root hair growth by controlling calcium levels.

research Mechanistic Underlying Anti-diabetic Potential of Eclipta alba Flavonoids against Aldose Reductase Inhibitory Action

1 citations , February 2025 in “South Asian Research Journal of Pharmaceutical Sciences”

Eclipta alba flavonoids may help treat diabetes by effectively inhibiting Aldose reductase.

research Bioguided Fraction and Isolation of the Antitumor Components fromPhyllanthus niruriL.

30 citations , January 2016 in “BioMed Research International”

Corilagin is the main antitumor component in Phyllanthus niruri, effective against cancer cells.

research Ivarmacitinib stimulates hair regrowth in severe alopecia areata

April 2025

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