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research Simultaneous determination of multi-class active pharmaceutical ingredients by UHPLC-HRMS
A new method was developed to accurately detect and measure 47 different drug ingredients in various products.
research Efficient Gene Editing for Heart Disease via ELIP-Based CRISPR Delivery System
ELIP-based CRISPR delivery improves heart disease gene editing but needs more testing.
research Dual drug co-encapsulation into liposomes and liposome-derived nanosystems for improved synergistic treatment of skin diseases
research “PRIDE” Complex
Certain cancer drugs can cause skin issues like rashes and itching.
research Local infusion of infliximab for the treatment of acute joint inflammation
Co-trimoxazole may help treat autoimmune diseases.
research Evolution of Ritlecitinib Population Pharmacokinetic Models During Clinical Drug Development
Ritlecitinib shows promise as a versatile treatment for various autoimmune and inflammatory diseases.
research EMULGEL EMERGENT SYSTEMS: AT A GLANCE FOR TOPICAL DRUG DELIVERY
Emulgels are effective for delivering skin medications and cosmetics due to their easy application and controlled release.
research 688 Precise and efficient editing of the COL7A1 gene in RDEB derived iPSCs with CRISPR/Cas9 and prime editing
CRISPR/Cas9 and prime editing can potentially fix skin disorder genes safely and effectively.
research Understanding the formation mechanism of drug-polymer inclusion complex by structure elucidation and theoretical calculation
The research shows how certain drug molecules form stable structures with polymers, which could help create new drug forms.
research Development and Characterization of In Situ Gelling Nasal Cilostazol Spanlastics
The developed nasal gel improves cilostazol delivery to the brain, enhancing its effectiveness and reducing side effects.
research BH02 Overcoming genetic drivers in alopecia areata: hair regrowth in a patient with the AIRE gene mutation treated with ruxolitinib
Ruxolitinib helped a woman with a genetic mutation regrow her hair and improved her health.
research Molecular insights into the formation of drug-polymer inclusion complex
The research shows how certain drugs can form stable structures with polymers, which is important for making new pharmaceuticals.
research Ishige sinicola extract stimulates osteoblast proliferation and differentiation via the bone morphogenetic protein 2/runt-related gene 2 signalling pathway
Ishige sinicola extract helps bone-building cells grow and mature, which could aid in treating osteoporosis.
research 15485 Evaluating the safety and efficacy of intense pulsed light with radiofrequency in US patients with hidradenitis suppurativa: A split-body study
Intense pulsed light with radiofrequency showed mixed results in improving quality of life for hidradenitis suppurativa patients, with no clinical improvements.
research Multiple minute digitate hyperkeratosis
The document concludes that fexofenadine reduces inflammation in chronic hives, cholestyramine helps half of pregnant women with itchy rashes, and relaxing incisions are a good alternative in facial surgery for the elderly.
research Pilot Clinical Evaluation of a Hyaluronic Acid– and Hydrogen Peroxide–Based Gel in the Management of Folliculitis: An Open-Label, Post-Marketing Study
The gel effectively reduced folliculitis symptoms and was safe to use.
research A New Strategy for Consumption of Functional Lipids from Ericerus pela (Chavannes): Study on Microcapsules and Effervescent Tablets Containing Insect Wax–Derived Policosanol
Microcapsules and effervescent tablets make insect lipids easier to consume.
research Emulgel: A Novel Approach For Hydrophobic Drugs
Emulgels effectively deliver hydrophobic drugs for skin conditions like acne and psoriasis.
research Ritlecitinib: First Approval
Ritlecitinib is approved in the USA and Japan for treating severe hair loss in people aged 12 and older.
research IPL sources and ruby lasers for hair reduction - trying to compare apples and oranges
Choose IPL for versatility and speed, ruby lasers for precision.
research Pre-keratin isolated from epidermal microsomes
research Active pharmaceutical ingredient-ionic liquids assisted follicular co-delivery of ferulic acid and finasteride for enhancing targeted anti-alopecia
The new delivery system improves treatment for hair loss by enhancing drug absorption and effectiveness.
research Novel Fish Oil-based Bigel System for Controlled Drug Delivery and its Influence on Immunomodulatory Activity of Imiquimod Against Skin Cancer
The fish oil-based gel with imiquimod improves skin cancer treatment and reduces inflammation.
research A Novel Epithelial Keratin, hK6irs1, is Expressed Differentially in All Layers of the Inner Root Sheath, Including Specialized Huxley Cells (Flügelzellen) of the Human Hair Follicle
A new keratin, hK6irs1, is found in all layers of the hair follicle's inner root sheath.
research Emulgel: A Novel Strategy for Enhanced the Topical Drug Delivery
Emulgel improves skin delivery of various drugs better than traditional methods.
research Molecular Docking Studies and ADME Prediction of Novel Isatin Analogs with Potent Anti-EGFR Activity
Some new isatin compounds could be strong cancer-fighting drugs because they fit well in cancer-related proteins and have good drug-like properties.
research Integrin-linked kinase inhibition via QLT0267 stops the epithelial outgrowth.
QLT0267 stops hair follicle cell growth and movement.
research Ruxolitinib found to cause eyelash growth: a case report
Ruxolitinib treatment may cause eyelash growth.
research Advances in the treatment of autosomal recessive congenital ichthyosis, a look towards the repositioning of drugs
Drug repositioning offers hope for new, affordable treatments for a genetic skin disorder called ARCI.