research Targeting the Hypoxic Microenvironment in Cutaneous Chronic Graft-Versus-Host Disease through PI3Kδ Inhibition
PI3Kδ inhibition may effectively treat cutaneous chronic graft-versus-host disease.
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600-630 / 1000+ resultsresearch Effect of laser diode light irradiation on growth capability of human hair follicle dermal papilla cells
Laser diode light boosts hair follicle cell growth and certain gene expressions.
research Proposition of a low cost field assay to determine antiproliferative properties of indigenous plants using Dugesia dorotocephala (brown planaria)
The study showed that brown planaria can be used to cheaply test if local plants can stop cell growth.
research Growth factors specifically alter hair follicle cell proliferation and collagenolytic activity alone or in combination
Growth factors can either promote or inhibit hair follicle cell growth and collagen breakdown.
research A preliminary study of differentially expressed genes in expanded skin and normal skin: implications for adult skin regeneration
The study found that expanded skin regenerates similarly to normal skin, with 77 genes playing a role in the process.
research PPAR-γ Agonists and Their Role in Primary Cicatricial Alopecia
PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.
research Deregulated expression of c-Myc depletes epidermal stem cells
research Pseudopelade of Brocq
Pseudopelade of Brocq is a unique hair loss condition, but its cause and development are still not fully understood.
research Norgalanthamine Stimulates Proliferation of Dermal Papilla Cells via Anagen-Activating Signaling Pathways
Norgalanthamine helps hair cells grow by activating certain pathways related to hair growth.
research Lineage Commitment of Dermal Fibroblast Progenitors is Mediated by Chromatin De-repression
Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.
research Temporal expression and steroidal regulation of piRNA pathway genes (mael, piwi, vasa) during Silurana (Xenopus) tropicalis embryogenesis and early larval development
The piRNA pathway genes are crucial in early development and may influence sex differentiation through hormone regulation.
research Synthesized Ceramide Induces Growth of Dermal Papilla Cells with Potential Contribution to Hair Growth
Synthetic ceramides may help hair growth by boosting cell growth in hair follicles.
research Primary TSC2-/meth Cells Induce Follicular Neogenesis in an Innovative TSC Mouse Model
TSC2-/meth cells can cause skin lesions, hair growth, and lung issues, and may be treated with chromatin remodeling agents.
research Premature aging syndromes: From patients to mechanism
Studying premature aging syndromes helps understand human aging and suggests potential treatments.
research A Case of Proliferating Trichilemmal Cyst with Trichoepitheliomatous Change
A young woman had a rare scalp tumor usually found in older women.
research Read-Through for Nonsense Mutations in Type XVII Collagen‒Deficient Junctional Epidermolysis Bullosa
A new therapy for a skin blistering condition has not been developed yet.
research Enhancement of Human Hair Growth UsingEcklonia cavaPolyphenols
Ecklonia cava polyphenols help increase human hair growth and reduce hair loss.
research Spatial transcriptomics of a giant pilomatricoma
The analysis of a large pilomatricoma revealed five distinct areas with different gene activity related to hair growth and tumor development.
research Does collapse of immune privilege in the hair-follicle bulge play a role in the pathogenesis of primary cicatricial alopecia?
Immune privilege collapse in hair follicles may cause permanent hair loss in certain conditions.
research PDGF isoforms induce and maintain anagen phase of murine hair follicles
PDGF isoforms can promote and sustain hair growth.
research Hair multiplication with dermal papilla like tissue containing human dermal papilla cells
Injecting lab-grown hair cells into the scalp can regrow hair.
research Disturbed Epidermal Structure in Mice with Temporally Controlled Fatp4 Deficiency
Fatp4 is crucial for healthy skin development and function.
research 1446 RNase L acts as a regeneration suppressor
RNase L suppresses regeneration in mammals.
research Increased dipicolinic acid production with an enhanced spoVF operon in Bacillus subtilis and medium optimization
Genetically modifying a bacteria and changing its growth conditions significantly increased the production of a chemical called dipicolinic acid.
research Pimecrolimus increases the melanogenesis and migration of melanocytes in vitro
Pimecrolimus boosts melanin production and movement of skin pigment cells.
research Signaling modality within gp130 receptor enhances tissue regeneration
The gp130 receptor helps in tissue regeneration and disease progression, and manipulating it could improve healing and prevent disease.
research Bulge cells of human hair follicles: segregation, cultivation and properties
Researchers found that bulge cells from human hair can grow quickly in culture and have properties of hair follicle stem cells, which could be useful for skin treatments.
research 311 Single-cell transcriptomics reveals distinct molecular programs in folliculotropic mycosis fungoides
Folliculotropic mycosis fungoides has unique molecular features and cell interactions that could guide targeted therapy.
research Transient mitochondrial DNA double strand breaks in mice cause accelerated aging phenotypes in a ROS-dependent but p53/p21-independent manner
Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.
research 1458 EMT-inhibiting transcription factor Ovol2 regulates directional cell migration and proliferation in adult skin epithelia
Ovol2 is important for proper skin healing and hair growth.