research Intracrine testosterone activation in human pancreatic β cells stimulates insulin secretion.
Testosterone in our bodies helps increase insulin secretion from the pancreas.
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840-870 / 1000+ results research Pan-tissue scaling of stiffness versus fibrillar collagen reflects contractility-driven strain that inhibits fibril degradation
Tissue stiffness is influenced by contractility, which suppresses collagen breakdown.
research Differential cold stress intensities drive unique morphological and transcriptomic changes in Zea mays root hairs
Maize root hairs adapt differently to mild and severe cold, with mild stress allowing some growth and severe stress stopping growth to focus on defense.
research Standardization and Validation of Scalp Surface Area Measurement and Assessment of Interchangeability Between Two Independent Methodologies for Head Crown Area and Total Hair Count Measurement
Two methods reliably measure scalp area and hair count.
research Systems Approach to Human Hair Fibers: Interdependence Between Physical, Mechanical, Biochemical and Geometric Properties of Natural Healthy Hair
Hair properties are interconnected; a comprehensive, cross-disciplinary approach is essential for understanding hair behavior.
research Evaluation of bioequivalence of five 0.1 mg dutasteride capsules compared to one 0.5 mg dutasteride capsule: a randomized study in healthy male volunteers
Taking five small dutasteride capsules is the same as taking one larger capsule.
research Allopregnanolone (AP) induces opioid inhibition of hypothalamo-pituitary-adrenal (HPA) axis responses to interleukin-1β (IL-1β) in pregnancy
Allopregnanolone and opioids together reduce stress hormone responses during pregnancy.
research Interspecies variations in response to topical application of selected zinc compounds
Different zinc compounds cause varying levels of skin irritation in animals.
research Topical Minoxidil Therapy for Androgenetic Alopecia-Reply
Minoxidil therapy can help with hair regrowth, but results vary and some people are just happy to stop further hair loss.
research Advancements in Drug Repurposing: Examples in Psychiatric Medications
Old psychiatric drugs are increasingly being used for new purposes, and technologies like SmartCube® help create new drugs.
research The Androgen Receptor and Its Use in Biological Assays: Looking Toward Effect-Based Testing and Its Applications
Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.
research Effect of X-Irradiation on Differentiating Hair Follicles
X-ray exposure affects developing hair follicles.
research De novo single-nucleotide and copy number variation in discordant monozygotic twins reveals disease-related genes
The research found genetic differences in identical twins that could explain why one twin has a disease while the other does not.
research Factors predicting response to oral methylprednisolone tapering treatment in alopecia areata: A retrospective study
Younger patients and those with more hair loss are less likely to benefit from oral steroid treatment for hair loss, and low vitamin D may predict relapse.
research Gene expression of type 2 17β hydroxysteroid dehydrogenase in scalp hairs of hirsute women
Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.
research Hirsutism scoring in polycystic ovary syndrome: concordance between clinicians' and patients' self-scoring
Patients with PCOS tend to score their hirsutism higher than clinicians, making self-scoring less useful for diagnosis.
research Effect of thioredoxin reductase 1 on glucocorticoid receptor activity in human outer root sheath cells
Thioredoxin reductase 1 does not affect glucocorticoid receptor activity in hair follicle cells.
research Two Different Mutations in the Same Codon of a Type II Hair Keratin (hHb6) in Patients with Monilethrix
Mutations in the hHb6 gene cause the hair disorder monilethrix.
research Connubial Androgenetic Alopecia
Hamilton scale imprecise, hair shaft diameter decreases, stem cell transplant regrows hair, ECP ineffective for alopecia areata universalis.
research Thymic Mesenchymal Cells Have a Distinct Transcriptomic Profile
Thymic mesenchymal cells have unique gene expression that supports their specific functions in the thymus.
research REVERSED SEQUENTIAL THERAPY OF HIRSUTISM USING CYPROTERONE ACETATE
Reversed sequential therapy with cyproterone acetate was effective for treating women with hirsutism and related conditions.
research Drug repurposing: Clinical practices and regulatory pathways
Drug repurposing offers faster, cheaper drug development but faces challenges like safety, ethics, and funding.
research Identification of a Rare Variant in the SRD5A2 Gene in Siblings With 46,XY Disorders of Sexual Development
A rare gene variant causes sexual development issues in siblings, needing personalized treatment.
research Circumscribed alopecia areata incognita
A rare form of alopecia causes hair thinning without bald spots and may be more common than thought, responding well to steroid treatment.
research Assessment of styling performance in hair gels and hair sprays by means of a new two-point stiffness test.
The new stiffness test works well for gels but not for sprays.
research Queries and Minor Notes
The reply suggests checking for false positive or asymptomatic syphilis and using penicillin for treatment if necessary.
research Hair transparency decoding in Asia: From stylists’ perception to in vitro measurement
Higher hair luminosity and shine mean higher perceived transparency.
research Shock: A possible presenting manifestation of autoimmune polyendocrine syndrome type II
Shock can be an early sign of Autoimmune Polyendocrine Syndrome Type II.
research Adherence to topical hydrocortisone 17-butyrate 0.1% in different vehicles in adults with atopic dermatitis
Adults with atopic dermatitis showed similar adherence to different forms of hydrocortisone cream, but actual use varied despite self-reports of near-perfect usage.