research The Majority of Multipotent Epidermal Stem Cells Do Not Protect Their Genome by Asymmetrical Chromosome Segregation
Most hair follicle stem cells do not protect their DNA by dividing it unevenly.
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210-240 / 1000+ results research Clinical Considerations of Bioequivalence for Topical Dermatologic Drugs
Current methods for assessing bioequivalence of topical drugs are limited and lack standardization.
research Herstellung eines Hautäquivalentes mit Hilfe von humanen Zellen der Haarwurzelscheide und Fibroblasten
A skin model using hair and skin cells can mimic human skin for research.
research Reproduction of the human relevant potency threshold (HRPT) for estrogen receptor alpha agonism in an inference performance screen for ICCVAM’s regulatory scientific confidence framework
A new method effectively predicts estrogen-related health effects for early screening.
research Phenotypic Heterogeneity in 5 Japanese Patients with an Identical Point Mutation in the Vitamin D Receptor Gene
Patients with the same vitamin D receptor mutation showed different symptoms due to other factors.
research Evaluating anti-LGBTQIA+ medical bias in large language models
Large language models often give biased or inaccurate medical responses, especially for LGBTQIA+ prompts.
research Strategies for Managing Suboptimal Response to JAK Inhibitors in Alopecia Areata
research 268 Use of ultra-fast one-step CK5 ihc for identifying bcc and scc during mohs surgery
A new one-step test can quickly identify skin cancer during surgery.
research Membrane androgen receptors may mediate androgen reinforcement
Androgen self-administration might be controlled by membrane receptors, not nuclear ones.
research 706 Predictive modeling of patient response to JAK/STAT inhibitors and dynamic patient-matching
Machine learning can predict how well patients with alopecia areata will respond to certain treatments.
research Sex-specific Difference of Hippocampal Synaptic Plasticity in Response to Sex Neurosteroids
Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.
research 1436 Lesional skin histology in drug-induced hypersensitivity syndrome: A single center 10-year experience of 37 patients
Interface dermatitis is the most common skin change in drug-induced hypersensitivity syndrome.
research Insulin resistance, nitric oxide, and fibrinogen levels in white hirsute women: Defining a new paradigm based on translational research
White hirsute women with PCOS have higher insulin resistance, but similar nitric oxide and fibrinogen levels compared to those with idiopathic hirsutism.
research A comment regarding ‘follicular Swiss cheese’ in the diagnosis of alopecia areata
The author clarifies that alopecia areata incognito and diffuse alopecia areata are different types of hair loss with unique symptoms and challenges in diagnosis.
research THE SHEPHERDS HOOK PHENOMENON PATTERN OF HAIR ROOTS A DEMONSTRATION OF COMPARATIVE BIOLECTROMAGNETISM BETWEEN HUMAN HAIRS AND MOUSE WHISKERS BY MEANS OF THE PHOTOELECTRIC EFFECT
Human hair and mouse whiskers emit similar biomagnetic fields.
research Characterizing Loss of Response Occurring in a Small Number of Patients During 3 Years of Long-Term Maintenance Therapy with Baricitinib 4-mg: Results From BRAVE-AA1 and -AA2 Trials
Some patients on Baricitinib for alopecia areata lost response, often linked to longer and more severe initial conditions.
research Learning from hair moisture sorption and hysteresis
Hair moisture behavior helps tell apart different chemical treatments and reveals insights into hair structure.
research Sensitisation to ethylhexyl salicylate: Another piece of the frontal fibrosing alopecia puzzle
Some people with Frontal Fibrosing Alopecia may be allergic to a common sunscreen ingredient.
research Restructuring skin equivalents with human hair follicle orscs and fibroblasts
A new method was developed to create better skin models for healing and reconstruction.
research Club-like receptors respond to light touch but not to whisking
Club-like receptors detect light touch but not whisking.
research Author response: Generation of inner ear hair cells by direct lineage conversion of primary somatic cells
Four transcription factors can convert mouse cells into hair cell-like cells, aiding hearing loss research and treatment.
research Analysis of clinical and histologic correlations in alopecia areata and telogen effluvium: adversities in alopecia pattern mimicry.
The study found that it's hard to tell the difference between two types of hair loss, alopecia areata and telogen effluvium, by looking at symptoms and tissue samples.
research Endogenous human skin equivalent promotes in vitro morphogenesis of follicle-like structures
Endo-HSE helps grow hair-like structures from human skin cells in the lab.
research Ixekizumab shows efficacy and safety in patients who failed biweekly etanercept therapy: Analysis From UNCOVER-2, a phase 3 randomized clinical trial in psoriasis
Ixekizumab is effective and safe for patients who did not improve with etanercept treatment for psoriasis.
research Immune system response to the Covid 19 virus and 3rd boosters
Third booster shots enhance the immune system's response to the COVID-19 virus.
research Bioequivalence of a single 10-mg dose of finasteride 5-mg oral disintegrating tablets and standard tablets in healthy adult male Han Chinese volunteers: A randomized sequence, open-label, two-way crossover study
Finasteride 5-mg oral disintegrating tablets and standard tablets are bioequivalent in healthy adult male Han Chinese volunteers.
research New Insight Into the Immunostaining Method Suitable for the Pilosebaceous Complex Unit
The study found that a one-step antibody method is better than the LSAB method for accurately studying hair follicle structures without false positives.
research Evidence for multiple, developmentally regulated isoforms of Ptprq on hair cells of the inner ear
Ptprq has multiple forms that change during inner ear development.
research The T-cell antigen receptor: paradigm recalled
research Multimodal Recruitment to Study Ovulation and Menstruation Health: Internet-Based Survey Pilot Study (Preprint)
Multimodal recruitment effectively gathered a diverse group for an online survey on ovulation and menstruation health.