research Breaking the “rule-of-five” to access Bridged Bicyclic Heteroaromatic Bioisosteres
A new method creates valuable compounds for drug discovery by breaking traditional chemical rules.
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research The effects and mechanisms of collagen peptides for alleviating skin ageing
Collagen peptides may help reduce skin aging by improving elasticity and hydration.
research Ionizable Coenzyme‐Engineered Lipid/Fiber Microplexes Boost Ribosomal Translation to Improve mRNA Therapy for Degenerative Diseases
New lipid/fiber microplexes improve mRNA therapy for degenerative diseases by enhancing cell function and treatment effectiveness.
research Design, Synthesis and Anxiolytic Activity Evaluation of N-Acyltryptophanyl- Containing Dipeptides, Potential TSPO Ligands#
The compound GD-23 may reduce anxiety like diazepam by targeting the TSPO receptor.
research Isolation and characterization of genomic clones of human sequences presumably coding for hair cysteine-rich proteins
A new protein linked to hair strength was identified, aiding in understanding brittle hair conditions.
research Programmable viscoelastic hydrogels exhibit antimicrobial and regenerative properties to promote cell migration, wound healing, and tissue remodeling
HA-gel-dex hydrogels help heal wounds and regenerate tissue effectively.
research Preparation and characterization of keratin-based biocomposite hydrogels prepared by electron beam irradiation
Keratin-based hydrogels from human hair and wool are promising for wound dressings and are more eco-friendly.
research The human tri-peptide GHK and tissue remodeling
The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.
research Cysteine contents of purified human hair low-sulfur protein components
research Some observations on the proteins of the inner root sheath cells of hair follicles
research Matrix effects and application of matrix effect factor
Matrix effects in LC-MS can be managed but not completely avoided.
research Laccase-catalyzed poly(tyrosine) grafting improves the performance of wool
Using laccase to add poly(tyrosine) to wool makes it less likely to shrink and stronger.
research CosmeticPotential of a Structural Protein CopolymerBased on Silk, Elastin, and Keratin
SELP::KP improves hair strength, elasticity, and health, making it a promising hair cosmetic.
research Reconnection of cysteine in reduced hair with alkylene dimaleates via thiol‐Michael click chemistry
A new method using 1,4-n-butylene dimaleate effectively repairs and strengthens damaged hair.
research Reduction mechanism of L ‐cysteine on keratin fibers using microspectrophotometry and Raman spectroscopy
L-cysteine slows down the breaking of bonds in hair due to electrostatic interactions.
research Bioorthogonal Catalytic Microneedles Based on a Cytotoxic PEI Matrix for Synergistic Melanoma Therapy
A new microneedle patch significantly improves melanoma treatment by using a special material to activate cancer-fighting drugs and disrupt cancer cells.
research Breaking the ‘rule-of-five’ to access bridged bicyclic heteroaromatic bioisosteres
A new method creates unique chemical structures that could improve drug discovery.
research Vertebral epidermal transamidases
Transamidases are present in the epidermis but their exact role is unclear.
research Bioactive Compounds in Neurocosmetics: Bridging Nature-Derived Peptides and Synthetic Molecules for Advanced Skin Health and Well-being
Bioactive compounds in neurocosmetics can improve skin health and emotional well-being.
research Antimicrobial peptide-modified AIE visual composite wound dressing for promoting rapid healing of infected wounds
The new wound dressing speeds up healing of infected wounds safely and effectively.
research Activating an adaptive immune response from a hydrogel scaffold imparts regenerative wound healing
A special gel scaffold was made that speeds up wound healing and skin regeneration, even though it breaks down faster than expected.
research Two-ligand priming mechanism for potentiated phosphoinositide synthesis is an evolutionarily conserved feature of Sec14-like phosphatidylinositol and phosphatidylcholine exchange proteins
A protein in plants needs to bind two lipids to help with root hair growth, and this process is similar across different plant species.
research Protective and Restorative Effects of a Bio-Based Crosslinking Complex on Chemically Damaged Hair
The bio-based complex effectively repairs and protects chemically damaged hair.
research Comparative proteomic analyses using iTRAQ-labeling provides insights into fiber diversity in sheep and goats
The research found specific proteins that affect fiber characteristics and hair growth in sheep and goats.
research The microfibrillar proteins of human hair: Separation by high-performance liquid chromatography and isolation of some proteins enriched in glycine and tyrosine
A new method isolated previously undetected hair proteins rich in glycine and tyrosine.
research Characterization of dermal type I collagen of C3H mouse at different stages of the hair cycle
Collagen remodeling is more active during hair growth stages.
research Immunofluorescent localization of collagen types I, III and IV, fibronectin, laminin, and basement membrane proteoglycan in developing mouse skin
research Insights on the mechanical behavior of keratin fibrils
Keratin's mechanical properties are influenced by hydrogen bonds and secondary structure, and can be improved with the SPD-2 peptide.
research Three strands ironed closely together
A new method was developed to create complex molecular knots using iron ions.
research The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Argireline significantly reduces wrinkles.