research Analysis of gene expression patterns and levels in maize hybrids and their parents
Maize hybrids show better early growth due to complex gene interactions from their parent strains.
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780-810 / 1000+ results research Concentration homeostasis and elements in hair and dried serum observed by X-ray fluorescence analysis using synchrotron radiation
Hair analysis can help diagnose cell ion channel activity and calcium deficiency.
research [Determination of finasteride in human plasma by HPLC-MS].
The two finasteride formulations are bioequivalent.
research COMPARAÇÃO ENTRE HPLC E IMUNOTURBIDIMETRIA PARA DOSAGEM DE HEMOGLOBINA GLICADA (A1C) COMO CRITÉRIO DIAGNÓSTICO DE DIABETES MELLITUS
HPLC may detect prediabetes and diabetes earlier than Immunoturbidimetry because it shows higher A1c levels.
research Genotype–Phenotype Correlation in Children With Congenital Adrenal Hyperplasia due to 21‐Hydroxylase Deficiency Using Next Generation Sequencing
Severe genetic variants in children with a specific adrenal condition match predicted symptoms well, but milder variants do not.
research In vitro bioassays for androgens and their diagnostic applications
In vitro bioassays are better than traditional methods for measuring androgen activity but aren't ready for routine use yet.
research Flow cytometric analysis of cell cycle kinetics of anagen scalp hair correlated with plasma androgens in hirsutism.
Higher DHEA-S levels in hirsute females affect hair growth phases.
research Beyond Spectral Similarity: How to Distinguish Polymorphs with Similar Solid‐State Circular Dichroism Anisotropy Spectra?
A new method using solid-state circular dichroism anisotropy can distinguish similar chiral compounds better than traditional techniques.
research Allosteric interactions prime androgen receptor dimerization and activation
Certain interactions help prepare the androgen receptor for pairing and activation, which is important for its role in development and disease.
research Investigating metabolic syndrome markers and body mass index changes in patients with acne vulgaris treated with isotretinoin: A prospective study
Isotretinoin effectively treats acne with low risk if dosed correctly.
research Apparent Hyperandrogenemia Due to Immunoassay Interference Resolved by Liquid Chromatography–Tandem Mass Spectrometry
False high testosterone levels were corrected using a more accurate test.
research Hair trace elementary profiles in aging rodents and primates: links to altered cell homeodynamics and disease
research Hair elemental status as a diagnostic parameter: achievements, challenges and opportunities
Analyzing hair for its elemental makeup can be useful for diagnosis, but there are still challenges and room for improvement.
research Creatine phosphokinase levels and isotretinoin therapy
Isotretinoin can raise CPK levels, so patients need monitoring, especially before surgery.
research Gas Chromatography Tandem Mass Spectrometry for Biomarkers of Alcohol Abuse in Human Hair
A new method quickly detects alcohol use from hair in under an hour.
research HORMONAL STATUS IN POSTMENOPAUSAL ANDROGENETIC ALOPECIA
No significant hormone differences found in postmenopausal women with androgenetic alopecia.
research Comparison of Novel Hematological Biomarkers in Alopecia Areata and Other Not-Cicatricial Alopecia: A Retrospective Study
Blood cell counts could help predict and treat alopecia areata and telogen effluvium.
research A novel human type I hair keratin gene: evidence for two keratin hHa3 isoforms
Scientists discovered two versions of a new human hair keratin gene.
research Natural variability and the influence of concurrent control values on the detection and interpretation of low-dose or weak endocrine toxicities.
Control variability makes it hard to confirm low-dose endocrine effects.
research LC-MS/MS-based reference intervals for hair cortisol in healthy children
Hair cortisol levels change with age, starting high at birth, decreasing until age 6, then rising to adult levels by age 18.
research Intracrine androgen biosynthesis, metabolism and action revisited
The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
research MicroRNA profiles of four induced pluripotent stem cell lines derived from distinct tissues
iPSC lines from different tissues share a common miRNA profile, supporting their pluripotent nature.
research Urinary Androgens Provide Additional Evidence Related to Metabolism and Are Correlated With Serum Androgens in Girls
The research found that measuring androgens in urine can give extra information about body metabolism and is linked to androgen levels in the blood, especially in young girls.
research Hair Analysis as an Indicator of Mineral Status of Livestock
Hair analysis is not a precise way to measure livestock's mineral status but can help when used with other methods.
research Machine learning-based steroid metabolome analysis reveals three distinct subtypes of polycystic ovary syndrome and implicates 11-oxygenated androgens as major drivers of metabolic risk
PCOS has three subtypes, with 11-oxygenated androgens increasing metabolic risk.
research Long-term detection of methyltestosterone (ab-) use by a yeast transactivation system
A yeast-based test can detect the steroid methyltestosterone in urine longer than traditional methods.
research Finasteride Quantification in Human Plasma by High-Performance Liquid Chromatography Coupled to Electrospray Ionization Tandem Mass Spectrometry. Application to a Comparative Pharmacokinetics Study
New method measures finasteride in plasma, finds two formulations bioequivalent.
research Relations between sex hormone level and characters of hair and skin in healthy young men
Higher androgen levels do not cause baldness in men.
research Colorimetric assay for γ-glutamyl transpeptidase
The document concludes that measuring γ-glutamyl transpeptidase activity is more accurate with a higher substrate concentration and using diluted acetic acid to stop the reaction.
research Element concentrations in serum, erythrocytes, hair and urine of alopecia patients
Alopecia patients had similar element levels to normal people, except for differences in copper and low selenium.