research Estrogen-Androgen Imbalance in Patients with Hirsutism and Amenorrhea
Low estrogen and high testosterone may cause excessive hair growth in women.
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research QSAR Analysis of a Series of Hydantoin‐based Androgen Receptor Modulators and Corresponding Binding Affinities
Researchers developed reliable models to predict how well certain compounds bind to androgen receptors, emphasizing the importance of atomic electronegativity.
research Hair mass index obtained by cross-section trichometry: an objective and clinically useful parameter to quantify hair in chemotherapy-induced alopecia
Hair mass index is a precise way to measure hair loss in chemotherapy patients.
research A different approach to hair analysis: Application to multiple sclerosis
Manganese levels in hair may be linked to multiple sclerosis.
research Ischemic modified albumin as a new biomarker in predicting of oxidative stress in alopecia areata
Ischemic modified albumin could be a new indicator of oxidative stress in people with alopecia areata.
research Discordant phenotype in monozygotic twins with mosaic trisomy 12p in lymphocytes
Identical twins had different symptoms because one had more cells with an extra chromosome fragment in different tissues.
research Accessing Properties of Molecular Compounds Involved in Cellular Metabolic Processes with Electron Paramagnetic Resonance, Raman Spectroscopy, and Differential Scanning Calorimetry
These methods help understand cell structures and reactions.
research Ornithine decarboxylase activity in relation to DNA synthesis in mouse interfollicular epidermis and hair follicles
research Towards the validation of endogenous steroid testing in wildlife hair
Hair analysis for stress and reproductive hormones in wildlife needs more research for accuracy across species.
research 144 Evaluation of contamination and quantification of drug penetrations studies using Quantitative Mass Spectrometry Imaging
QMSI effectively maps and quantifies drug distribution in skin tissues.
research Preliminary pharmacokinetics and metabolism of novel non-steroidal antiandrogens in the rat: Relation of their systemic activity to the formation of a common metabolite
Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.
research Androgen Profile Through Life in Women With Polycystic Ovary Syndrome: A Nordic Multicenter Collaboration Study
Women with PCOS have higher androgen levels that decrease with age but are still higher than in women without PCOS.
research Invalidation of a commercially available human 5α-dihydrotestosterone immunoassay
The DHT immunoassay is unreliable due to high cross-reactivity with testosterone.
research 5α-Reductase isozymes and aromatase mRNA levels in plucked hair from young women with female pattern hair loss
Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.
research In Silico Promoter Motif Analysis of Human Fertility-Related Genes
The study found potential new DNA patterns in fertility genes, but further testing is needed.
research Synthesis and structure–activity studies of side-chain derivatized arylhydantoins for investigation as androgen receptor radioligands
The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.
research Serum-Based Assessment of Alopecia Areata Response to Treatment Using ATR-FTIR Spectroscopy
ATR-FTIR spectroscopy could help monitor alopecia areata treatment response non-invasively.
research Analysis of hair steroid hormone concentrations at different parts of the head by liquid chromatography-tandem mass spectrometry
Hormone levels in hair vary across the head, with the highest concentration of a key hormone linked to hair loss at the top.
research Age-specific cut-off levels of anti-Müllerian hormone can be used as diagnostic markers for polycystic ovary syndrome
Different levels of anti-Müllerian hormone can help diagnose polycystic ovary syndrome in women of different ages.
research Uptake of mercury by the hair of methylmercury-treated newborn mice
Methylmercury accumulates in mouse hair during growth, then decreases when growth stops.
research In vitro [7-3H]-testosterone metabolism by the rat ventral prostate—Effect of some exogenous compounds
research The mechanisms and functions of interorganelle interactions
Different parts of cells interact at specific areas to control cell functions like energy production and fat storage.
research Update on the combination of myo-inositol/d-chiro-inositol for the treatment of polycystic ovary syndrome
Myo-inositol and D-chiro-inositol, especially in a 40:1 ratio, effectively treat PCOS by improving insulin sensitivity and ovulation.
research A long-term follow-up study of men born with very low birth weight and their reproductive hormone profile
Men born very underweight had higher estrogen levels but normal reproduction compared to normal birth weight men.
research Circulating testosterone and feather-gene expression of receptors and metabolic enzymes in relation to melanin-based colouration in the barn owl
Barn owls with smaller black spots have higher testosterone levels, which might be due to genetic effects on hormone regulation rather than hormone effects on coloration.
research Alopecia areata incognita: a comment
The author clarified that Alopecia Areata Incognita (AAI) and diffuse Alopecia Areata (AA) are different conditions and the case discussed was actually AA, not AAI.
research Sphingolipid Metabolites Profiling in Hair Growth
DHCer levels in hair could be a biomarker for alopecia progression.
research Omega-6 highly unsaturated fatty acids in Leydig cells facilitate male sex hormone production
Omega-6 fats in certain cells boost male hormone production.
research Analysis of gene expression patterns and levels in maize hybrids and their parents
Maize hybrids show better early growth due to complex gene interactions from their parent strains.
research Tentative reference ranges for calcium and strontium in Spanish children’ scalp-hair.
Girls in Alcalá have higher hair calcium and strontium levels than boys, with lower overall levels than other regions.