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Isoallopregnanolone may be a safe and effective treatment for reducing tics in a mouse model of Tourette syndrome.

Tsc2-deficient stem cells can help understand and treat TSC-related tumors.

A gene mutation in mice causes skin defects and early death.

The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.

A new keratin 6 type in mice explains why some mice without certain keratin genes still have normal hair and nails.

Brindled mice show abnormal catecholamine neuron development due to copper deficiency.

Disrupting the Tsc2 gene in certain cells leads to thicker skin, larger hair, and changes in hair growth signaling, which can be partly reversed with specific treatment.

Researchers created a new mouse model for studying scleroderma.

Meis2 is essential for touch sensation and nerve function in mice.

Mutations in the Sgk3 gene cause fuzzy hair in mice.

Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.

Trps1 is essential for proper hair follicle development.

The hairless mutant gene causes early hair loss and affects skin and thymus development in mice.

Ovariectomy in mice affects hair growth and skin thickness, suggesting potential for obesity treatment research.

Activating Tgr5 may help treat hair loss and bone loss.

Removing PLCg1 from skin cells caused thicker oil glands and less hair in mice.

Mice with extra sheep genes had hair that fell out and regrew in cycles.

Removing HIF-P4H-2 from certain skin cells in mice causes hair loss on the body but not the head.

K6 gene expression can be controlled and manipulated in mice for studying skin disorders.

Mice genetically modified to produce more Del1 protein had faster hair regrowth.

LGD1069 effectively prevents breast tumors in mice without toxicity.

Overexpressing thrombospondin-1 in mice skin prevents UVB-induced skin damage.

Smad2 and Smad3 are essential for normal skin development, and their absence causes severe skin issues and cancer.

Deleting Snai2 and Snai3 causes fatal autoimmunity.

The system allows precise control of gene expression in mouse skin, useful for studying skin biology.

Too much parathyroid hormone-related protein in skin disrupts hair growth in mice.

Abnormal keratin expression in mice causes severe oral issues, affecting feeding.

Mouse Scube3 affects teeth, tongue, vibrissae, and eye development, but not facial structure or limb growth.