research Hair Follicle Chemosensation: TRPM5 Signaling Is Required for Anagen Maintenance
TRPM5 is crucial for maintaining hair growth.
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research Update on Melasma—Part I: Pathogenesis
Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.
research SnapshotDx Quiz: May 2020
BIVV009 is a safe treatment for bullous pemphigoid that reduces C3 deposition without harmful side effects.
research Claudin Expression Modulations Reflect an Injury Response in the Murine Epidermis
Claudin expression changes help the skin respond to injury.
research Delayed Cutaneous Wound Healing and Aberrant Expression of Hair Follicle Stem Cell Markers in Mice Selectively Lacking Ctip2 in Epidermis
Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.
research Keratins as an Inflammation Trigger Point in Epidermolysis Bullosa Simplex
Mutant keratins cause inflammation in Epidermolysis Bullosa Simplex, suggesting targeting them could help treat the disorder.
research Skin-specific expression of a truncated E1a oncoprotein binding to p105-Rb leads to abnormal hair follicle maturation without increased epidermal proliferation.
The oncoprotein causes abnormal hair growth without increasing skin cancer risk.
research Hair Follicle Pigmentation
Hair color is determined by melanin produced and transferred in hair follicles.
research Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment
Myc activation reduces skin stem cells by affecting cell adhesion.
research Do Hair Bulb Melanocytes Undergo Apotosis During Hair Follicle Regression (Catagen)?
Hair follicle melanocytes die during hair regression.
research Necl2 regulates epidermal adhesion and wound repair
Necl2 affects skin cell behavior and slows wound healing.
research The cellular basis of mechanosensory Merkel-cell innervation during development
BMP signaling is essential for the development of touch domes.
research Recessive Epidermolysis Bullosa Simplex Phenotype Reproduced in Vitro
Fibroblasts from healthy donors can prevent changes seen in recessive epidermolysis bullosa simplex.
research Autophagy: Guardian of Skin Barrier
Autophagy helps keep skin healthy and may improve treatments for skin diseases.
research The Developmental & Molecular Requirements for Ensuring that Human Pluripotent Stem Cell-Derived Hair Follicle Bulge Stem Cells Have Acquired Competence for Hair Follicle Generation Following Transplantation
Scientists found the best time to transplant human stem cells for hair growth is between days 16-18 when they have the right markers and growth potential.
research Fabrication of Bioactive Helix aspersa Extract-Loaded Chitosan-Based Bilayer Wound Dressings for Skin Tissue Regeneration
Snail secretion-loaded dressings can improve skin regeneration and wound healing.
research Molecular and Cellular Characterization of Avian Reticulate Scales Implies the Evo–Devo Novelty of Skin Appendages in Foot Sole
Bird foot scales develop differently and can repair but not fully regenerate due to the lack of specialized stem cell areas.
research 574 Murine sebaceous gland homeostasis requires intact cutaneous innervation in a hair cycle-dependent context
Mouse skin glands need healthy nerves to grow properly during hair growth phases.
research Spatial and temporal control of laminin-511 and -332 expressions during catagen
Laminin-511 may help promote hair growth, while laminin-332 does not affect hair loss.
research Through the lens of hair follicle neogenesis, a new focus on mechanisms of skin regeneration after wounding
Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.
research Mechanical forces in skin disorders
Skin problems can be caused or worsened by physical forces and pressure on the skin.
research Immunopathogenesis of Primary Cicatricial Alopecia
Hair loss in Lichen Planopilaris is caused by immune system issues damaging hair follicles and stem cells.
research Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions
New effective scar treatments are urgently needed due to the current options' limited success.
research The human keratins: biology and pathology
Keratins are crucial for cell stability, wound healing, and cancer diagnosis.
research Control of hair growth and follicle size by VEGF-mediated angiogenesis
VEGF helps hair grow and determines follicle size by increasing blood vessel growth.
research Diversity of Adult Stem Cell Niches in the Dermal Compartment of Skin
The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
research Identification of Distinct Immune Signatures and Chemokine Networks in Scalp Inflammatory Diseases
Different immune responses cause hair loss in scalp diseases, with unique patterns in scalp psoriasis possibly protecting against hair loss.
research What does acne genetics teach us about disease pathogenesis?
Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.
research Multi‐tasking epidermal stem cells: Beyond epidermal maintenance
Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.
research Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions
The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.