22 citations
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February 2007 in “Developmental neurobiology” Hormones and sex affect potassium channel gene expression in electric fish, influencing their communication signals.
28 citations
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August 2013 in “Hypertension” Potassium channel openers help form elastic fibers in arteries and can treat elastin deficiency and hypertension.
19 citations
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February 2016 in “Journal of Biological Chemistry” KCNQ potassium channels help control the sensitivity of touch receptors in the skin.
18 citations
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October 2020 in “Journal of Pharmacology and Experimental Therapeutics” KATP channel openers may cause peripheral edema by reducing lymphatic contractions and flow.
9 citations
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June 2017 in “Pharmacological Reports” ATP-sensitive potassium channels play a role in chloroquine-induced itch in mice.
April 2024 in “Archives of toxicology” Certain substances can protect against ear damage from some antibiotics in zebrafish.
January 2022 in “Function” Studying rare genetic disorders can help us understand and treat common diseases better.
75 citations
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August 2018 in “Biochemical pharmacology” Targeting the skin's endocannabinoid system could help treat skin disorders.
67 citations
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December 2019 in “PloS one” Beta-caryophyllene helps improve wound healing in mice, especially in females.
16 citations
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January 2011 in “Archives of Dermatological Research” The study found that expanded skin regenerates similarly to normal skin, with 77 genes playing a role in the process.
February 2024 in “Frontiers in physics” The new model detects hair clusters more accurately and efficiently, helping with early hair loss treatment and diagnosis.
152 citations
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April 2012 in “Recent Patents on Inflammation & Allergy Drug Discovery” Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.
82 citations
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March 2016 in “Autoimmunity reviews” Animal models have helped understand hair loss from alopecia areata and find new treatments.
47 citations
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October 1989 in “Circulation Research” The study explains how minoxidil sulfate causes vasodilation in rabbits by opening potassium channels and inhibiting calcium channels.
29 citations
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February 2021 in “Cancers” Ion channels play a key role in ovarian cancer growth and treatment resistance.
13 citations
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June 2023 in “Frontiers in Molecular Neuroscience” Blocking the KATP channel may help treat migraines.
123 citations
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November 2003 in “Neuroscience Letters” TRPV4 helps sense pressure in mouse skin.
106 citations
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April 2010 in “ACS Nano” C60 fullerenes can alter protein function and may help develop new disease inhibitors.
55 citations
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June 2013 in “Dermatologic Surgery” Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.
48 citations
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October 2011 in “Sports Medicine” Ice-skating athletes often have skin problems due to cold, infections, and inflammation, needing careful treatment and prevention.
42 citations
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March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
29 citations
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November 2013 in “Expert Review of Dermatology” Sensitive skin often causes discomfort, affects many people, especially women and older adults, and should be managed with careful product selection.
28 citations
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September 2021 in “EMBO reports” Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.
27 citations
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June 2013 in “Genes & development” Cav1.2 affects hair growth and could be a target for hair loss treatments.
22 citations
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November 2018 in “Brazilian Journal of Pharmaceutical Sciences” New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.
15 citations
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December 2020 in “The Journal of General Physiology” Acid can block TRPV3 from outside the cell but boost its function from inside.
14 citations
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February 2024 in “Biomolecules” TRPV channels are important in osteoarthritis and could be key to new treatments.
10 citations
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August 2014 in “PLoS ONE” Hair follicles can help diagnose traumatic brain injury quickly and non-invasively.
8 citations
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July 2022 in “Frontiers in plant science” pH changes are crucial for root hair growth because they affect enzymes and proteins that control the cell wall and growth.
7 citations
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January 2020 in “Journal of Dermatology” Cantu syndrome, which causes excessive hair growth and skin issues, is due to a mutation in the ABCC9 gene, and understanding this could help develop new treatments for hair diseases.