research Against the Rules: Human Keratin K80
Keratin K80 is an ancient protein found in various tissues, important for cell structure and tissue differentiation.
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600-630 / 721 resultsresearch Dynamic expression of Runx1 in skin affects hair structure
Runx1 is crucial for proper hair structure and development.
research The empowering influence of air-liquid interface culture on skin organoid hair follicle development
Air-liquid interface culture improves hair follicle development in skin organoids.
research Keratins as an Inflammation Trigger Point in Epidermolysis Bullosa Simplex
Mutant keratins cause inflammation in Epidermolysis Bullosa Simplex, suggesting targeting them could help treat the disorder.
research Dermatologic manifestations of thyroid disease: a literature review
Thyroid disease can cause skin, hair, and nail problems, and treating the thyroid condition often improves these symptoms.
research Ex vivo detection of SARS CoV 2 spike protein in human hair follicles and potential link to telogen effluvium
COVID-19 may cause hair loss by affecting hair follicles.
research Prevention of chemotherapy drug-mediated human hair follicle damage: combined use of cooling with antioxidant suppresses oxidative stress and prevents matrix keratinocyte cytotoxicity
Cooling with antioxidants helps protect hair during chemotherapy.
research Hes1 regulates anagen initiation and hair follicle regeneration through modulation of hedgehog signaling
Hes1 protein is important for hair growth and regeneration, and could be a potential treatment for hair loss.
research Aging in the sebaceous gland
Sebaceous glands age due to genetic and environmental factors, affecting sebum production and composition.
research Keratins and disease at a glance
Keratins are crucial for tissue strength, and mutations in keratin genes can lead to various diseases, highlighting the need for targeted therapies.
research Emerging Role of Dermal White Adipose Tissue in Modulating Hair Follicle Development During Aging
Fat tissue under the skin affects hair growth and aging; reducing its inflammation may help treat hair loss.
research The role of hair follicles and Edar signalling in cutaneous wound healing
Activating the Eda/Edar pathway improves wound healing by enhancing hair follicle growth.
research 1381 Molecular mechanisms of donor dominance in androgenetic alopecia
Hair pattern in androgenetic alopecia overlaps with scalp and bone demarcations, with distinct gene profiles affecting susceptibility.
research Thyroid diseases and skin autoimmunity
Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.
research Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice
Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.
research Resting no more: re‐defining telogen, the maintenance stage of the hair growth cycle
The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.
research The human type I keratin gene family: Characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain
The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.
research Regeneration of Hair Follicles Is Modulated by Flightless I (Flii) in a Rodent Vibrissa Model
Flightless I protein affects hair growth, with low levels delaying it and high levels increasing hair length in rodents.
research Keratin disorders: from gene to therapy
New treatments targeting specific genes show promise for treating keratin disorders.
research Pro‐Regenerative Hydrogel Restores Scarless Skin during Cutaneous Wound Healing
A special hydrogel helps heal skin without scars and regrows hair.
research Lack of Collagen VI Promotes Wound-Induced Hair Growth
Mice without collagen VI have slower hair growth normally but faster regrowth after injury.
research Hair-cycle dependent differential expression of ADAM 10 and ADAM 12
ADAM 10 and ADAM 12 proteins are involved in different stages of hair growth and could be targets for treating hair disorders.
research TLR2 regulates hair follicle cycle and regeneration via BMP signaling
TLR2 is important for hair growth and can be targeted to treat hair loss.
research Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update
The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
research Characterization of a 190-Kilobase Pair Domain of Human Type I Hair Keratin Genes
The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.
research Convergent Evolution of Cysteine-Rich Keratins in Hard Skin Appendages of Terrestrial Vertebrates
Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.
research Over-expression of thymosin beta4 promotes abnormal tooth development and stimulation of hair growth
Too much thymosin beta4 causes weird teeth and more hair growth in mice.
research Transcriptome sequencing reveals the expression profiles of lncRNAs and mRNAs in goat skin tissues with different types of wool coats
The study identified key genes and pathways that influence goat wool quality and growth.
research Neuroendocrine Controls of Keratin Expression in Human Skin
Neurohormones help control skin health and could treat skin disorders.
research A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth
A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.