research Live imaging reveals chromatin compaction transitions and dynamic transcriptional bursting during stem cell differentiation in vivo
Stem cell differentiation involves gradual chromatin changes and dynamic gene activity.
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840-870 / 1000+ resultsresearch Natural role of stem cells and their Potential for Tissue Regeneration and as Disease Treatment in the aging Population
Stem cell therapy shows promise for regenerating tissues and treating diseases, especially in older people.
research Restoration of hair-inductive activity of cultured human follicular keratinocytes by co-culturing with dermal papilla cells
Growing hair cells with dermal cells can potentially treat hair loss.
research Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity
The human scalp has different types of pigment cells in hair follicles with varying abilities to produce pigment.
research Establishment and molecular characterization of human dermal mesenchymal-like stem cells derived from human scalp biopsy of androgenetic alopecia patient
Researchers created a cell line from a hair follicle to study hair loss.
research The Stem Cell Niche
Understanding stem cell environments is key to developing treatments for various diseases and injuries.
research Overexpression of human keratin 16 produces a distinct skin phenotype in transgenic mouse skin
High levels of human keratin 16 in mice cause skin lesions and abnormal skin development.
research Analysis of Sequences Controlling Tissue-Specific and Hyperproliferation-Related Keratin 6 Gene Expression in Transgenic Mice
K6 gene expression can be controlled and manipulated in mice for studying skin disorders.
research Cell Population Dynamics in Wound-Induced Hair Follicle Neogenesis Model
Non-immune dermal cells dominate, epidermal cells increase after day 9, and certain immune cells persist beyond inflammation in wound-induced hair follicle regeneration.
research Many Paths to Alopecia via Compromised Regeneration of Hair Follicle Stem Cells
Different problems with hair stem cell renewal can lead to hair loss.
research LncRNA H19 inhibited dermal papilla cell senescence process through miR-29a by targeting Wnt/β-catenin signaling pathway
H19 may help prevent hair loss by keeping hair cells young.
research Defining The Role of Primary Cilia on Skin Derived Precursors.
Elongating cilia boosts SKP stem cell renewal, especially with PDGF.
research Establishment of an immortalized mouse dermal papilla cell strain with optimized culture strategy
Researchers created a long-lasting mouse skin cell strain that may help with hair growth research and treatments.
research Dedifferentiation of committed epithelial cells into stem cells in vivo
Certain mature cells in mouse lungs can turn back into stem cells to aid in tissue repair.
research Understanding Melanocyte Stem Cells for Disease Modeling and Regenerative Medicine Applications
Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.
research stem cell translation and bioethics
The document concludes that stem cell therapies lack solid proof of effectiveness, except for blood system treatments, and criticizes the ethical issues and commercial exploitation in the field.
research Fully functional hair follicle organ regeneration using organ-inductive potential stem cells with an accessory mesenchymal cell population in an in vitro culture system
Scientists successfully regenerated functional hair follicles using specific stem cells and mesenchymal cells.
research RhoA promotes epidermal stem cell proliferation via PKN1-cyclin D1 signaling
RhoA helps skin stem cells grow, aiding wound healing.
research Impaired Lef1 activation accelerates iPSC-derived keratinocytes differentiation in Hutchinson-Gilford Progeria Syndrome
Impaired LEF1 activation speeds up skin cell development in Hutchinson-Gilford Progeria Syndrome.
research 376 Tsc2 disruption in mesenchymal progenitors regulates hair follicles and TGF beta signaling
Disrupting the Tsc2 gene in certain cells leads to thicker skin, larger hair, and changes in hair growth signaling, which can be partly reversed with specific treatment.
research Distinct tooth regeneration systems deploy a conserved battery of genes
Different species use the same genes for tooth regeneration.
research Induced Pluripotent Stem Cell Approach to Hair Follicle Regeneration
iPSCs could help develop treatments for hair loss.
research Cutaneous stem cells: something new and something borrowed
Epidermal stem cells maintain skin health through specific niches and signaling pathways.
research Experimental dataset for: Hair follicle neural crest stem cell-derived exosomes promote peripheral nerve regeneration via miR-214-3p
Hair follicle stem cell exosomes help nerve regeneration.
research 1365 Elf5, a novel regulator of skin stem/progenitor cells fate during skin development?
Elf5 is important for skin stem cell growth and could help treat skin and hair problems.
research Stem cell niches in mammals
Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.
research Dermal Microvascular Responses of Human Induced Pluripotent Stem Cell–Derived Skin Organoids to Inflammation and Injury
Skin organoids can mimic human skin responses to injury and inflammation, making them useful for studying skin diseases and testing treatments.
research Abstract 3889: Cyclin-dependent kinase 4 levels affect the number of hair follicle stem cells in mouse epidermis
CDK4 levels affect the number of hair follicle stem cells in mice.
research Exosomes derived from Umbilical cord mesenchymal stem cell promote hair regrowth in C57BL6 mice through upregulation of the RAS/ERK signaling pathway
Exosomes from stem cells help hair regrowth by activating a specific signaling pathway.
research Adipose Derived Stem Cells and Growth Factors Applied on Hair Transplantation. Follow-Up of Clinical Outcome
Using adipose derived stem cells and growth factors in hair transplants may improve healing and hair growth.