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Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome KATP Channel Mutations in Intact Cells

research Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome K_ATPChannel Mutations in Intact Cells

1 citations , August 2023 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics”

Kir6.1 mutations in Cantú syndrome increase channel sensitivity and hyperpolarization, while SUR2B mutations do not.

research LGR5 is a Marker of Poor Prognosis in Glioblastoma and is Required for Survival of Brain Cancer Stem‐Like Cells

82 citations , July 2012 in “Brain pathology”

High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.

Non-Invasive Assessment of Hair Regeneration in Androgenetic Alopecia Mice In Vivo Using Two-Photon and Second Harmonic Generation Imaging

research Non-invasive assessment of hair regeneration in androgenetic alopecia mice in vivo using two-photon and second harmonic generation imaging

September 2023 in “Biomedical Optics Express”

New imaging techniques show testosterone delays hair growth and shrinks follicles in mice, but have limited depth for viewing.

research Coat Color in Intact and Neurointermediate Lobe-Grafted Agouti Mice: Effect of Dopamine Agonists and Antagonists

4 citations , January 1982 in “Neuroendocrinology”

Dopamine affects coat color changes in agouti mice.

research Targeted Overexpression of the Angiogenesis Inhibitor Thrombospondin-1 in the Epidermis of Transgenic Mice Prevents Ultraviolet-B-Induced Angiogenesis and Cutaneous Photo-Damage

93 citations , May 2002 in “Journal of Investigative Dermatology”

Overexpressing thrombospondin-1 in mice skin prevents UVB-induced skin damage.

research A BIOCHEMICAL MARKER IN A DOMINANT MOUSE TRAIT

April 1974 in “Pediatric Research”

The Naked (N) trait in mice is linked to lower glycine and tyrosine in hair proteins.

research Linking chromatin dynamics, cell fate plasticity, and tissue homeostasis in adult mouse hair follicle stem cells

3 citations , July 2017 in “Endogenous locus-driven H-Ras G12V expression induces senescence-like phenotype in primary fibroblasts of the Costello syndrome mouse model”

Mouse hair follicle stem cells have a flexible chromatin state that supports skin health and hair growth.

research Platelet-rich plasma improves caspase-3 of skin graft treated with Tilapia Mozambique bio-dressing

January 2025 in “Open Veterinary Journal”

PRP with TM bio-dressing improves skin graft healing in cats.

research Role of phosphatidylinositol 3‐kinase signaling pathway in radiation‐induced liver injury

6 citations , July 2020 in “The Kaohsiung Journal of Medical Sciences”

Inhibiting the PI3K/Akt pathway may help prevent radiation-induced liver injury.

research Expression of truncated latent TGF-β-binding protein modulates TGF-β signaling

40 citations , May 2005 in “Journal of Cell Science”

Truncated LTBP-1 disrupts TGF-β signaling, affecting hair growth.

research Gene-knockout mice with abnormal epidermal and hair follicular development

11 citations , November 1998 in “Journal of dermatological science”

Knocking out certain genes in mice helps understand skin and hair growth problems.

research T-Cell Reconstitution after Thymus Xenotransplantation Induces Hair Depigmentation and Loss

7 citations , January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology”

T-cell reconstitution after thymus transplantation can cause hair whitening and loss.

research 057 Single cell RNA and TCR sequencing reveals hyperexpansion of T cell clones and novel regulatory mechanisms of CD8+ T cells in murine alopcecia areata skin and draining lymph nodes

July 2024 in “Journal of Investigative Dermatology”

CD8+ T cells expand significantly in alopecia areata, suggesting new treatment targets.

research Extradermal melanin transfer? Lack of macroscopic spleen melanization in old C57BL/6 mice with de-synchronized hair cycle.

10 citations , June 2009 in “Acta Biochimica Polonica”

Old C57BL/6 mice with unsynchronized hair cycles show less melanin in their spleens.

research Intracellular protons accelerate aging and switch on aging hallmarks in mice

4 citations , August 2018 in “Journal of cellular biochemistry”

Acid inside cells speeds up aging and turns on aging signs in mice.

research Absence of vitamin D receptor (VDR)‐mediated PPARγ suppression causes alopecia in VDR‐null mice

12 citations , December 2016 in “The FASEB Journal”

Lack of vitamin D receptor causes hair loss in mice by allowing certain genes to overactivate.

research Genetic alterations involved in the expression of the coloring of tortoiseshell and calcial hair in domestic cats males: review.

January 2019 in “PubVet”

research A subpopulation of itch‐sensing neurons marked by Ret and somatostatin expression

70 citations , February 2016 in “EMBO reports”

Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.

research Expression of novel keratin associated protein 5 genes in the cuticle layer of human hair follicles

6 citations , April 2005 in “Journal of dermatological science”

The study found nine new hair protein genes in human hair follicles.

research 1336 The de novo DNA methyltransferase DNMT3A is required for epidermal homeostasis

April 2018 in “Journal of Investigative Dermatology”

DNMT3A is crucial for healthy skin and hair growth.

research Characterization of a gene encoding a cysteine-rich keratin associated protein synthesized late in rabbit hair follicle differentiation

26 citations , March 1995 in “Differentiation”

A rabbit gene important for hair development was identified and detailed.

research Phenotyping mice with skin, hair, or nail abnormalities: A systematic approach and methodologies from simple to complex

2 citations , May 2023 in “Veterinary Pathology”

Understanding genetic variations in mice is crucial for studying skin, hair, or nail abnormalities.

research Curly bare (cub), a new mouse mutation on chromosome 11 causing skin and hair abnormalities, and a modifier gene (mcub) on chromosome 5

29 citations , January 2003 in “Genomics”

A new mouse mutation causes skin and hair issues, influenced by another gene.

research The Effect of Copper Supplementation on the Brindled Mouse

40 citations , July 1981 in “Journal of Neuropathology & Experimental Neurology”

Copper injections improved symptoms and prevented brain damage in brindled mice.

research ANTI-AGING EFFECTS OF MESENCHYMAL STEM CELL-CONDITIONED MEDIUM IN MICE SKIN MODEL INDUCED BY D-GALACTOSE

July 2017

MSC-CM improved aged skin in mice.

research Mice lacking the epidermal retinol dehydrogenases SDR16C5 and SDR16C6 display accelerated hair growth and enlarged meibomian glands

16 citations , September 2019 in “Journal of biological chemistry/The Journal of biological chemistry”

Mice without certain skin enzymes have faster hair growth and bigger eye glands.

research Additional file 3 of ROS-responsive hydrogel-delivered miR-665 targets STAT3 to alleviate inflammation and promote hair follicle regeneration in alopecia areata

February 2026 in “Figshare”

research Additional file 3 of ROS-responsive hydrogel-delivered miR-665 targets STAT3 to alleviate inflammation and promote hair follicle regeneration in alopecia areata

February 2026 in “Figshare”

research Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state

25 citations , June 2022 in “Developmental cell”

Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.

research A homozygous single T deletion found in the GGCX gene with PXE-like phenotypes

September 2016 in “Journal of Dermatological Science”

A gene mutation worsens skin irritation in mice due to a lack of certain fats.

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