January 2009 in “ScholarlyCommons (University of Pennsylvania)” The P133R mutation in AKR1D1 enzyme causes harmful bile acid buildup, explaining related health issues.
52 citations
,
October 1995 in “Experimental Cell Research” Human hair keratin genes hHa2 and hHb1 are located on chromosomes 17 and 12.
Diseased horse foot skin shows increased keratin expression, similar to wound healing in mammals.
10 citations
,
January 2023 in “Annals of Dermatology” The guidelines recommend effective systemic treatments for alopecia areata in Korea.
July 2007 in “Manuals in biomedical research” 10 citations
,
January 2010 in “International journal of trichology” Keratin-associated proteins are part of the developing hair fiber cuticle.
22 citations
,
August 2015 in “PloS one” Keratin from hair binds well to gold and BMP-2, useful for bone repair.
38 citations
,
January 2014 in “Journal of Dermatological Science” Krtap11-1 is important for hair strength and structure.
2 citations
,
October 2023 in “JURNAL ILMU KEFARMASIAN INDONESIA” Kenikir leaf extract nanosuspension may help inhibit breast cancer cell growth.
April 2023 in “Journal of Investigative Dermatology” Dkk4 protein helps control how hair grows and its arrangement.
45 citations
,
January 2010 in “Journal of Veterinary Medical Science” A gene mutation causes curly hair and hair loss in rats.
2 citations
,
November 2019 in “Cancer reports” The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.
18 citations
,
January 2013 in “Veterinary Dermatology” K15 is a reliable marker for studying stem cells in dog hair follicle tumors.
8 citations
,
March 2007 in “International Journal of Cosmetic Science” 6-O glucose linoleate helps human hair grow and produce lipids.
9 citations
,
January 2017 in “Virchows Archiv” LGR5 and LGR6 are expressed differently in various skin tumors, which may offer clues about their origins.
April 2026 in “Tissue Engineering and Regenerative Medicine”
June 2024 in “British Journal of Dermatology” KRT14 gene variants cause dermatopathia pigmentosa reticularis, affecting nails, teeth, and hair.
March 2023 in “JAAD case reports” A new genetic change in the keratin 10 gene caused a skin condition called ichthyosis hystrix in a father and his daughter.
9 citations
,
November 2023 in “Supportive Care in Cancer”
72 citations
,
June 2001 in “Journal of Investigative Dermatology” S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.
37 citations
,
November 2007 in “Journal of Biological Chemistry” Ku80 is a key receptor for Thymosin β4, affecting cell migration and wound healing.
9 citations
,
November 2022 in “Biology” Key genes and pathways influence wool traits in Merino sheep.
September 2025 in “Annals of Plastic Surgery” Inverted follicular keratosis on the eyelid can be cured with surgery and has a great prognosis.
January 2026 in “International Ayurvedic Medical Journal” Ayurvedic treatment improved hair loss in a 23-year-old male.
65 citations
,
September 2010 in “Journal of the Neurological Sciences” Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.
9 citations
,
June 2019 in “JAAD case reports” Laser hair removal can help treat acne keloidalis nuchae, but results vary and a standard scoring system is needed.
63 citations
,
December 1998 in “Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology” The study improved understanding of keratin fiber structure by showing consistent microfibril diameter but varying distances and electron density profiles.
2 citations
,
September 1997 in “Archives of Dermatology” 15 citations
,
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.
Activating CB1 can reduce keratin levels, potentially helping manage psoriasis and aid wound healing.