research SFRP2/DPP4 and FMO1/LSP1 Define Major Fibroblast Populations in Human Skin
Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.
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research Integrated Transcriptomics and Metabolomics Analyses of Stress-Induced Murine Hair Follicle Growth Inhibition
Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.
research Medical Reasoning with Large Language Models: A Survey and MR-Bench
Large language models struggle with accurate clinical decision-making compared to real-world needs.
research Hair follicle gene expression profiling in the SubPopulations and InteRmediate Outcome Measures in COPD Study (SPIROMICS)
Hair follicles can be used to study gene expression and understand conditions like COPD.
research Defining stem cell dynamics and migration during wound healing in mouse skin epidermis
Stem cells help heal wounds by rapidly dividing and migrating to the wound edge.
research Metformin or Antiandrogen in the Treatment of Hirsutism in Polycystic Ovary Syndrome
Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.
research Effects of Flutamide and Finasteride on Rat Testicular Descent
Androgens, like testosterone, are crucial for early testicular descent in rats.
research A Simple Screening Approach for Assessing Community Prevalence and Phenotype of Polycystic Ovary Syndrome in a Semiurban Population in Sri Lanka
A simple screening method found that 6.3% of women in a semiurban area in Sri Lanka have polycystic ovary syndrome, with most showing menstrual irregularities.
research Systemic Steroids With or Without 2% Topical Minoxidil in the Treatment of Alopecia Areata
Steroids help hair regrowth, and minoxidil slows post-steroid hair loss, but effects are temporary.
research Hair Follicle Regeneration Using Grafted Rodent and Human Cells
Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.
research KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin
EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.
research Relationship of the metabolic syndrome and obesity to polycystic ovary syndrome: A controlled, population-based study
Metabolic syndrome and PCOS are related but separate conditions, with metabolic syndrome increasing the risk of heart disease and diabetes.
research Effects of Nitric Oxide on Skin Burn Wound Healing
Nitric oxide gel helps heal skin burns faster by improving skin growth, hair regrowth, and blood vessel formation.
research Lip and Perioral Reconstruction
Reconstruct lips with proper planning, templates, and revisions for appearance and function.
research Treatment with and withdrawal from finasteride alter ethanol intake patterns in male C57BL/6J mice: Potential role of endogenous neurosteroids?
Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.
research Minoxidil therapy in children with severe hypertension
Minoxidil helps lower high blood pressure in kids, but can cause fluid retention and hair growth.
research Self-microemulsifying systems of Finasteride with enhanced oral bioavailability: multivariate statistical evaluation, characterization, spray-drying and in vivo studies in human volunteers
Improved Finasteride delivery for hair loss treatment.
research Whole Body and Regional Hemodynamic Effects of Minoxidil in the Conscious Dog
Minoxidil lowers blood pressure, increases heart rate, and improves blood flow in dogs.
research Planar cell polarity-dependent and independent functions in the emergence of tissue-scale hair follicle patterns
Mice can correct hair follicle orientation without certain genes, but proper overall alignment needs those genes.
research Metabolic aspects of different phenotypes of polycystic ovary syndrome: Iranian PCOS Prevalence Study
The study suggests that being overweight or obese, not PCOS itself, is strongly linked to insulin resistance.
research The influence of sulfur and hair growth on stable isotope diet estimates for grizzly bears
Sulfur slightly improved diet estimates for grizzly bears, but hair growth timing varied, affecting results.
research Eyelash Growth from Application of Bimatoprost in Gel Suspension to the Base of the Eyelashes
Bimatoprost gel makes eyelashes grow longer, but may cause side effects and should be monitored by an eye doctor.
research Serum lipocalin-2 as an insulin resistance marker in patients with polycystic ovary syndrome
Lipocalin-2 levels are higher in women with PCOS and may indicate insulin resistance.
research Variation in human hair ultrastructure among three biogeographic populations
Different populations have distinct hair structures related to their ancestry.
research Normal Pubertal Development in Daughters of Women With PCOS: A Controlled Study
Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.
research Androgenetic Alopecia: In Vivo Models
Stump-tailed macaque best for researching hair loss causes and treatments.
research Genome-wide association study of skin complex diseases
Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.
research A missing piece: the spiny mouse and the puzzle of menstruating species
The spiny mouse is a unique menstruating rodent that can help us understand menstruation and reproductive disorders.
research Rooster feathering, androgenic alopecia, and hormone-dependent tumor growth: What is in common?
Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.
research Defining the identity of mouse embryonic dermal fibroblasts
Researchers identified specific genes that are important for mouse skin cell development and healing.