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An Uncontrolled Innovative Test of Cryo-Chilled Carbon Dioxide as a Novel Amplification of a Nano-Botanical Multi-Acting Therapy in Advanced Stage Androgenetic Alopecia

research An Uncontrolled Innovative Test of Cryo-Chilled Carbon Dioxide as A Novel Amplification of a Nano-Botanical Multi-Acting Therapy in Advanced Stage Androgenetic Alopecia (Aga)

March 2025

The treatment showed promising hair regrowth in advanced-stage hair loss.

research Protocol for Self-Assembled Human Hair Keratins

July 2007 in “Manuals in biomedical research”

research 880 Triptolide (TRP), a diterpenoid, shows a strong efficacy and a safe profile in the topical treatment of actinic keratosis lesions in a UV-B-induced mouse model

April 2017 in “Journal of Investigative Dermatology”

Triptolide effectively and safely reduces actinic keratosis lesions in mice.

research Gpr54 deletion accelerates hair cycle and hair regeneration

1 citations , November 2024 in “EMBO Reports”

Deleting Gpr54 speeds up hair growth and regeneration.

research Overexpression of parathyroid hormone-related protein in the skin of transgenic mice interferes with hair follicle development.

211 citations , February 1994 in “Proceedings of the National Academy of Sciences”

Too much parathyroid hormone-related protein in skin disrupts hair growth in mice.

research 576 A preliminary study of melanogenic markers in the differentiation of the human hair follicle melanin unit

November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

The study found markers indicating that cells responsible for hair color are differentiating in specific areas of the hair follicle.

research HR Gene Variants Identified in Mexican Patients with Alopecia Areata

6 citations , April 2023 in “Current Issues in Molecular Biology”

A specific gene variant may increase the risk of developing Alopecia Areata.

research Expression of NAD+dependent 15-hydroxyprostaglandin dehydrogenase and protection of prostaglandins in human hair follicle

11 citations , March 2008 in “Experimental Dermatology”

A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.

research A Unique Type I Keratin Intermediate Filament Gene Family is Abundantly Expressed in the Inner Root Sheaths of Sheep and Human Hair Follicles

41 citations , January 2001 in “Journal of Investigative Dermatology”

research Proteoglycans and Associated Proteins of the Mammalian Hair Follicle

7 citations , May 1995 in “The journal of investigative dermatology/Journal of investigative dermatology”

research Atypical Protein Kinase C Isoform, aPKCλ, Is Essential for Maintaining Hair Follicle Stem Cell Quiescence

24 citations , June 2015 in “Journal of Investigative Dermatology”

aPKCλ is crucial for keeping hair follicle stem cells inactive and maintaining normal hair growth.

research KY19382 Accelerates Cutaneous Wound Healing via Activation of the Wnt/β-Catenin Signaling Pathway

18 citations , July 2023 in “International Journal of Molecular Sciences”

KY19382 speeds up wound healing by activating a specific cell signaling pathway.

research Frequency of an electrophoretic variant of hair alpha keratin in human populations.

14 citations , January 1977 in “PubMed”

The hair keratin variant is mostly found in Caucasians.

Medications Affecting the Insulin-Like Growth Factor 1/Growth Hormone Axis, Including Teprotumumab, Somatostatin Analogs, and Anti-Calcitonin Gene-Related Peptide Monoclonal Antibodies, Are Associated With Elevated Reporting Odds of Alopecia in Women: A Pharmacovigilance Study

research Medications affecting the insulin-like growth factor 1/growth hormone axis, including teprotumumab, somatostatin analogs, and anti-calcitonin gene-related peptide monoclonal antibodies, are associated with elevated reporting odds of alopecia in women: A pharmacovigilance study

April 2023 in “Journal of The American Academy of Dermatology”

Some drugs linked to growth hormones may increase the chance of hair loss in women.

research Novel and established potassium channel openers stimulate hair growth in vitromodes of action in hair follicles.: implications for their

January 2005

Potassium channel openers like minoxidil boost hair growth.

research Expression of Keratin 75 (K6hf) in Oral Squamous Cell Carcinoma

2 citations , January 2011 in “Dental Medicine Research”

Keratin 75 might be important in oral cancer progression.

research Modulating testosterone pathway: a new strategy to tackle male skin aging?

6 citations , September 2012 in “Clinical Interventions in Aging”

Honokiol might help reduce male skin aging by maintaining testosterone levels.

research UDP-GlcNAc-1-Phosphotransferase Is a Clinically Important Regulator of Human and Mouse Hair Pigmentation

10 citations , June 2021 in “Journal of Investigative Dermatology”

research Dissection of a Complex Enhancer Element: Maintenance of Keratinocyte Specificity but Loss of Differentiation Specificity

42 citations , June 2002 in “Molecular and Cellular Biology”

Keratinocyte gene expression is controlled by multiple modules with specific binding sites.

research Identification of the Ovine Keratin-Associated Protein 22-1 (KAP22-1) Gene and Its Effect on Wool Traits

42 citations , January 2017 in “Genes”

The gene KAP22-1 affects wool yield and fiber shape in sheep.

research The retarded hair growth ( rhg ) mutation in mice is an allele of ornithine aminotransferase ( Oat )

9 citations , January 2014 in “Molecular Genetics and Metabolism Reports”

The rhg mutation in mice affects the Oat gene, causing hair growth issues and other symptoms.

The Main Cause of Hair Rarefaction in Androgenetic Alopecia: Higher Number and Longer Duration of Kenogen Hairs

research The Higher Number and Longer Duration of Kenogen Hairs Are the Main Cause of the Hair Rarefaction in Androgenetic Alopecia.

5 citations , November 2018 in “Skin appendage disorders”

More kenogen hairs cause hair thinning in androgenetic alopecia, not hair miniaturization.

research BMP2-mediated PTEN enhancement promotes differentiation of hair follicle stem cells by inducing autophagy

24 citations , September 2019 in “Experimental cell research”

BMP2 helps hair follicle stem cells become specialized by increasing PTEN, which causes autophagy.

research Bone morphogenetic proteins 4 and 2/7 induce osteogenic differentiation of mouse skin derived fibroblast and dermal papilla cells

28 citations , November 2013 in “Cell and Tissue Research”

Androgen Receptor Transactivity Is Potentiated by TGF-β1 Through Smad3 but Checked by Its Coactivator Hic-5/ARA55 in Balding Dermal Papilla Cells

research Androgen receptor transactivity is potentiated by TGF-β1 through Smad3 but checked by its coactivator Hic-5/ARA55 in balding dermal papilla cells

19 citations , September 2011 in “Journal of Dermatological Science”

TGF-β1 increases androgen receptor activity in hair loss, but Hic-5/ARA55 can counter this effect.

research Design and synthesis of novel androgen receptor antagonists with sterically bulky icosahedral carboranes

45 citations , August 2005 in “Bioorganic & medicinal chemistry”

New compounds with carborane showed anti-androgen effects similar to flutamide.

research Gene Expression in Rat Dermal Papilla Cells: Analysis of 2529 ESTs

14 citations , October 2000 in “Genomics”

Rat dermal papilla cells have unique genes crucial for hair growth.

research Effects of steroid hormones on the expression of Ca2+ activated K+ channels in in vitro pituitary cells of Atlantic cod (Gadus morhua)

January 2014 in “Duo Research Archive (University of Oslo)”

Steroid hormones may affect sexual maturation in cod by altering certain KCa channel expressions.

research The crest phenotype in domestic chicken is caused by a 195 bp duplication in the intron of HOXC10

29 citations , January 2021 in “G3 Genes Genomes Genetics”

A 195 bp duplication in the HOXC10 gene causes crests in domestic chickens.

research [Analysis of human hair basic keratin 6 gene mutation in a Chinese Han family with monilethrix].

2 citations , April 2008 in “PubMed”

A gene mutation causes monilethrix in a Chinese family.

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