research First-in-human phase 1 study of ETC-159 an oral PORCN inhbitor in patients with advanced solid tumours.
ETC-159 was safe up to 30 mg, but no tumor shrinkage was seen.
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900-930 / 1000+ resultsresearch Progestogens with Antiandrogenic Properties
research Formulation and evaluation of repurposed ketoconazole‐loaded transferosomal gel for enhanced trichogenic effects
The ketoconazole gel improved hair growth and is a promising treatment for hair loss.
research Study on the mechanism of cyclosporin A in stimulating hair growth
Cyclosporin A helps hair grow by increasing certain growth factors.
research Role of Anticonvulsant and Antiepileptogenic Neurosteroids in the Pathophysiology and Treatment of Epilepsy
Neurosteroids show promise for treating epilepsy and more research is needed.
research Neonatal neurosteroid levels are determinant in shaping adult prepulse inhibition response to hippocampal allopregnanolone in rats
Neonatal neurosteroid levels affect adult brain function and behavior.
research Tribal Colleges and University Project - Native American Internships
Anionic squarticles can effectively counteract amitriptyline overdose, improving survival rates.
research Analysis of the finasteride treatment and its withdrawal in the rat hypothalamus and hippocampus at whole-transcriptome level
Finasteride treatment in rats changed the expression of genes related to psychiatric and neurological functions, and these changes persisted after stopping the drug.
research Effect ofCitrullus colocynthis. on Hair Growth in Albino Rats
Citrullus colocynthis extract is effective for hair growth, comparable to minoxidil.
research A new target for squamous cell skin cancer?
Prostaglandins and the enzyme AKR1C3 could play a role in skin cancer and hair loss, and further research is needed to understand these mechanisms.
research Molecular Interactions of New Pregnenedione Derivatives
The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.
research Evaluation of Antiarthritic and Antinociceptive Effects of Cedrol in a Rat Model of Arthritis
Cedrol may help treat rheumatoid arthritis due to its anti-inflammatory and antioxidant effects.
research Wedelolactone: A Natural Anti-inflammatory Coumarin Derivative
Wedelolactone may help treat chronic diseases due to its strong antioxidant properties.
research Effects of adenosine triphosphate on vandetanib induced skin damage in rats
ATP helps prevent skin damage from vandetanib by reducing stress.
research Involvement of neurosteroids in the control of prolactin secretion in sheep under basal, stressful and pregnancy conditions
Neurosteroids affect prolactin levels in sheep differently depending on stress and pregnancy conditions.
research Encapsulación en ciclodextrinas de compuestos con actividad frente a la alopecia androgénica masculina.
Encapsulating hair loss drugs in cyclodextrins improves their solubility and reduces scalp irritation.
research Synthesis and biological activity of raltitrexed-carrier conjugates.
Raltitrexed conjugates are less potent than the free drug but more effective at high concentrations.
research Estudio de 2 suplementos nutricionales (cápsulas y espray) en el tratamiento de la alopecia femenina. Estudio KAIDAX
Two nutritional supplements improved hair growth and reduced hair loss in women with hair loss conditions.
research Lactium: A Novel Drug for Psychocutaneous Skin Disorders
Lactium, a milk protein, can help reduce symptoms of skin disorders linked to stress and anxiety without side effects.
research Topical cetirizine for the management of androgenic alopecia: Results of a pilot study
Topical cetirizine may help increase hair length in male pattern baldness and could be an alternative to minoxidil with fewer side effects.
research Effect of Neurosteroid Withdrawal on Hippocampal GABA‐A Receptor α4‐Subunit Expression in Female Mice
Neurosteroid withdrawal increases α4 subunit expression in the hippocampus, which may relate to catamenial epilepsy in women.
research Insight into Recent Advances in Degrading Androgen Receptor for Castration-Resistant Prostate Cancer
New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.
research THE CLINICAL SIGNIFICANCE OF METAL BINDING IN CONVULSION CONTROL WITH SODIUM VALPROATE
Metal binding to sodium valproate may be linked to hair loss in epilepsy patients.
research ANÁLISE MICROBIOLÓGICA DE MATÉRIAS-PRIMAS E FORMULAÇÕES DE UMA FARMÁCIA DE MANIPULAÇÃO NA CIDADE DE VENÂNCIO AIRES/RS
The compounding pharmacy in Venâncio Aires generally follows good practices, with only the Paracetamol sample showing significant microbial growth.
research 3P's (Pharmacokinetic, Pharmacodynamic, and Pharmacogenomic) of Valproate: What's New?
New information shows Valproate may protect the brain and reduce breathing failure risk but can cause liver damage and other side effects, with genetics affecting dosage needs.
research Testosterone, cytochrome P450, and cardiac hypertrophy
Heart-specific steroid metabolism is crucial in cardiac hypertrophy.
research Cerebellar Changes in Guinea Pig Offspring Following Suppression of Neurosteroid Synthesis During Late Gestation
research Sodium Valproate in Treatment of Epilepsy
Sodium valproate effectively reduces seizures in epilepsy, especially in absences and myoclonic types, with minimal side effects.
research Bud fruitfulness assessment and pruning
Different tissues in cows have different types of cytokeratins.