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Bridging Personal and Population in Excitability Diseases: Will Studies of Rare Diseases Bring Generalizable Mechanisms From Monogenic Channelopathies?

research Bridging Personal and Population in Excitability Diseases: Will Studies of Rare Diseases Bring Generalizable Mechanisms From Monogenic Channelopathies?

January 2022 in “Function”

Studying rare genetic disorders can help us understand and treat common diseases better.

research Evaluating the Role of lncRNAs in the Incidence of Cardiovascular Diseases in Androgenetic Alopecia Patients

May 2022 in “Cardiovascular Toxicology”

research Tea Polyphenol–Zinc Nanocomplexes Alleviate Diquat-Induced Liver and Small Intestine Oxidative Stress in C57BL/6 Mice

August 2025 in “Nanomaterials”

Tea polyphenol–zinc helps protect the liver and intestines from oxidative stress.

research Therapeutic efficacy and safety of Kang-ai injection combined with platinum-based doublet chemotherapy in advanced NSCLC: A meta-analysis

13 citations , August 2018 in “Life sciences”

Kang-ai injection with platinum-based chemotherapy improves tumor response and immune function while reducing side effects in advanced lung cancer.

research Structural Analyses of the Transient Receptor Potential Channels TRPV3 and TRPV6

January 2019 in “Columbia Academic Commons (Columbia University)”

TRPV3 and TRPV6 channels change structure to regulate calcium and heat responses.

research The Possible Involvement of KATP Channels in Cholestatic Pruritus in Mice

July 2024 in “Research Square (Research Square)”

KATP channels may help reduce itching in liver disease.

research A novel point mutation of keratin 17 (KRT17) in a Japanese family with pachyonychia congenita type 2: an RNA-based genetic analysis using a single hair bulb

5 citations , June 2008 in “British Journal of Dermatology”

research Connexin 43 expression in the testes during postnatal development of finasteride-treated male rat offspring

3 citations , February 2017 in “Archives of Medical Science”

Finasteride treatment changes Cx43 in rat testes, possibly causing fertility issues.

research Calcineurin/Nuclear Factor of Activated T-Cell Pathway in Cutaneous Squamous Cell Carcinoma

August 2019 in “International journal of dermatology and venereology”

The calcineurin/NFAT pathway plays a significant role in the development and growth of a type of skin cancer called cutaneous squamous cell carcinoma.

research CLED: A Calcium-Linked Protein Associated with Early Epithelial Differentiation

33 citations , August 2000 in “Experimental Cell Research”

research Message of protease nexin-1 is expressed in human dermal papilla cells and is affected by androgen

March 1998 in “Journal of dermatological science”

Protease Nexin-1 is found in human hair growth cells and is affected by male hormones.

research KY19382, a novel activator of Wnt/β-catenin signaling, promotes hair re-growth and hair follicle neogenesis

June 2020

KY19382 helps to regrow hair and create new hair follicles.

research Polygenic control of the wavy coat of the NCT mouse: involvement of an intracisternal A particle insertional mutation of the protease, serine 53 (Prss53) gene, and a modifier gene

January 2022 in “Mammalian Genome”

The wavy coat in NCT mice is caused by multiple genes, including a mutation in the Prss53 gene.

research TRPV3 Ion Channel: From Gene to Pharmacology

2 citations , May 2023 in “International Journal of Molecular Sciences”

The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.

research Tcf3 promotes cell migration and wound repair through regulation of lipocalin 2

55 citations , June 2014 in “Nature Communications”

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

$Synthesis and Structural Characterization of a New Dinuclear Platinum(III) Complex, [Pt2Cl4(NH3)2{μ-HN=C(O)Bu^t}2]$

research Synthesis and structural characterization of a new dinuclear platinum(III) complex, [Pt₂Cl₄(NH₃)₂{μ-HN=C(O)Bu^t}₂]

2 citations , November 2022 in “Acta crystallographica. Section B, Structural science, crystal engineering and materials./Acta crystallographica. Section B, Structural science, crystal engineering and materials”

A new platinum complex was made and studied, which might help fight cancer better.

research 478 Mutation-specific siRNA Knockdown of GJB2 − Potential gene therapy for Keratitis-ichthyosis-deafness Syndrome

April 2017 in “Journal of Investigative Dermatology”

Targeted siRNA therapy may be a promising treatment for KID syndrome by reducing mutant gene expression and improving cell communication.

research Tuning Scaffold Properties of New 1,4-Substituted Pyrrolo[3,2-c]quinoline Derivatives Endowed with Anticancer Potential, New Biological and In Silico Insights

December 2025 in “Biomolecules”

Compound 7p shows strong potential as an anticancer agent.

research The PER3 rs772027021 SNP induces pigmentation phenotypes of dyschromatosis universalis hereditaria

2 citations , September 2022

The PER3 rs772027021 SNP may cause mild skin pigmentation changes in a new subtype of dyschromatosis universalis hereditaria.

research Study the Structure and Dynamics of Antifungal Agent Ketoconazole by CSA and Site-Specific Spin-Lattice Relaxation Time Measurements

March 2021 in “Research Square (Research Square)”

Ketoconazole's structure and dynamics are linked, aiding antifungal drug development.

research The CAP1/Prss8 catalytic triad is not involved in PAR2 activation and protease nexin‐1 (PN‐1) inhibition

14 citations , August 2014 in “The FASEB Journal”

CAP1/Prss8 does not activate PAR2 or inhibit PN-1.

research Activity and Safety of Cinchonine Nanostructured Lipid Carriers as a Hair Growth Stimulant in Mice Model of Androgenetic Alopecia

June 2023 in “Sains Malaysiana”

Cinchonine Nanostructured Lipid Carriers serum safely and effectively stimulates hair growth and increases the number and size of hair follicles.

research Loss-of-Function Mutations in HOXC13 Cause Pure Hair and Nail Ectodermal Dysplasia

74 citations , October 2012 in “The American Journal of Human Genetics”

Mutations in the HOXC13 gene cause hair and nail development issues.

research Effect of K+ channel openers on K+ channel in cultured human dermal papilla cells.

20 citations , August 1997 in “PubMed”

Increased K+ permeability alone may not promote hair growth.

research Correlation and regression analysis of the KRT27 and ELOVL4 genes in cashmere fineness and other production performances in Liaoning cashmere goats

February 2025 in “Archives animal breeding/Archiv für Tierzucht”

Certain gene combinations improve cashmere quality and production in Liaoning goats.

research Ion Sequential Therapy Aligned With Pathological Changes Enhances Cardiac Function After Myocardial Infarction

September 2024

Ion sequential therapy improves heart function after a heart attack.

research Dyeing behaviours of amino heterocyclic compounds as blue oxidative hair dye precursors applied to keratin fibres

5 citations , January 2011 in “International Journal of Cosmetic Science”

1,2,3,4-tetrahydroquinoline compounds are great for stable, pure blue hair dye.

research Dissolving microneedles incorporating kopexil multicomponent crystals for improved transdermal delivery

January 2026 in “Drug Delivery and Translational Research”

Multicomponent crystals in microneedles improve drug delivery for hair loss treatment.

research First-in-human phase 1 study of ETC-159 an oral PORCN inhbitor in patients with advanced solid tumours.

33 citations , May 2017 in “Journal of Clinical Oncology”

ETC-159 was safe up to 30 mg, but no tumor shrinkage was seen.

research Abstract 1835: Development of mammary hyperplasia, dysplasia, and invasive ductal carcinoma in transgenic mice expressing the 8p11 amplicon oncogene NSD3 (WHSC1L1)

1 citations , July 2017 in “Cancer Research”

Overexpressing NSD3 in mice causes breast cancer-like tumors and gland abnormalities.

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