January 2017 in “Enlighten: Publications (The University of Glasgow)” Activating β-catenin and inactivating PTEN cause follicular tumors, not papillomas, similar to those in Cowden’s Disease.
1 citations
,
April 2020 in “European Journal of Dermatology” Apremilast showed mixed results for hair regrowth in alopecia areata.
May 2024 in “British journal of dermatology/British journal of dermatology, Supplement” Hair follicles in androgenetic alopecia age faster, especially in the front.
May 2018 in “Journal of Investigative Dermatology” Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.
12 citations
,
January 1991 in “Acta Dermato Venereologica” Basal cell epithelioma-like changes are most similar to normal basal cells.
September 2020 in “Advances in anatomic pathology” A woman's large nose growth was initially misdiagnosed, but later confirmed to be giant rhinophyma after full removal and examination.
128 citations
,
October 2011 in “Development” Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.
September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.
93 citations
,
May 1990 in “The EMBO Journal” Mice with extra sheep genes had hair that fell out and regrew in cycles.
January 2022 in “Stem cell biology and regenerative medicine” New hair can grow at wound sites, which could help improve treatments for hair loss and wound healing.
8 citations
,
September 2020 in “Genes & Genomics”
17 citations
,
April 2017 in “PLoS ONE” Hair follicle cells can become bone-like cells, useful for bone repair.
February 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” Hair follicles protect melanocytes from sun damage, helping them replenish skin.
May 2026 in “Organoid Research” Hydrogel-based hair follicle organoids could help treat hair loss and improve drug testing.
94 citations
,
February 1994 in “The journal of investigative dermatology/Journal of investigative dermatology” EGF makes hair follicles grow longer but stops hair production.
January 2008 in “Bradford Scholars (University of Bradford)” Alopecia areata may be caused by antibodies targeting specific hair follicle proteins, hindering hair growth.
30 citations
,
December 2001 in “Experimental dermatology” Gonadal hormones significantly affect the severity of alopecia areata in mice.
January 2008 in “Journal of The American Academy of Dermatology” ROS may affect hair loss related to hormones.
February 2022 in “Authorea (Authorea)” PAON shows skin patterns due to genetic mosaicism.
July 2016 in “Cancer research” Mutant cells in hair follicles are influenced by their location and interactions with surrounding cells.
January 2003 in “Journal of the Fourth Military Medical University” Hair follicles can regenerate if cut at certain points, with stem cells in the upper part.
79 citations
,
March 1999 in “The journal of investigative dermatology/Journal of investigative dermatology” Procyanidin compounds from grape seeds were found to significantly increase mouse hair growth.
3 citations
,
November 2010 in “The Journal of Dermatology” A giant blue nevus on the scalp can cause hair loss and may damage underlying structures.
46 citations
,
August 2012 in “Experimental Dermatology” Engineered skin can grow chimeric hair follicles only with mouse dermal papilla cells.
6 citations
,
August 2006 in “Journal of Cutaneous Pathology” Two teenage brothers had a rare, treatment-resistant form of female-pattern hair loss with unusual scalp changes.
21 citations
,
October 2017 in “Journal of Investigative Dermatology” The document concludes that understanding dermal papilla cells is key to improving hair regeneration treatments.
Melanocytes can regenerate around hair follicles in bullous pemphigoid, especially in patients with darker skin.
26 citations
,
January 2019 in “Experimental Dermatology” Researchers created early-stage hair-like structures from skin cells, showing how these cells can self-organize, but more is needed for complete hair growth.
57 citations
,
October 1996 in “Dermatologic clinics” HA-MNs with MXD effectively treat hair loss better than topical MXD with fewer side effects.
124 citations
,
April 1992 in “Journal of Endocrinology/Journal of endocrinology” Beard hair follicles have more androgen receptors than non-balding scalp hair follicles.