84 citations
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December 2018 in “Genetics in Medicine” Pegvaliase is recommended for treating adults with phenylketonuria.
September 2023 in “Journal of the American Academy of Dermatology” January 2004 in “Data Archiving and Networked Services (DANS)” Finasteride blocks progesterone's effect on brain activity linked to epilepsy.
November 2022 in “Indian Journal of Dermatology/Indian journal of dermatology” Valproic acid can cause dark lines on nails.
119 citations
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June 2005 in “Journal of Molecular and Cellular Cardiology” Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.
5alpha-DHP may be a safe, effective treatment for certain seizures without causing sedation.
4 citations
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January 2018 in “General Physiology and Biophysics” The steroids allopregnanolone and allotetrahydrodeoxycorticosteron worsened absence seizures in rats.
February 2009 in “Mayo Clinic proceedings” A woman's new seizures were caused by a brain tumor likely linked to her past cancer treatment, and choosing safe seizure medications is important for women who can have children.
26 citations
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July 2012 in “Epilepsy & Behavior” Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.
January 2016 in “International journal of clinical pediatrics” Valproic acid may cause temporary hair changes like loss or thinning in children.
May 2021 in “American journal of medical sciences and medicine” Sodium valproate caused vomiting in 20% of children under 2 years old, with other side effects like hair loss and loss of appetite also noted.
December 2025 in “Bolu Abant Izzet Baysal Universitesi Tip Fakultesi Abant Tip Dergisi” Minoxidil did not significantly affect epilepsy in rats.
11 citations
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January 2018 in “International journal of trichology” Valproate can cause hair loss and changes in hair appearance, but may help regrow hair when applied topically.
January 2016 in “Refubium (Universitätsbibliothek der Freien Universität Berlin)” CAP7.1 is generally safe at 200 mg/m²/day, but can cause fatigue, nausea, hair loss, fever, and blood-related issues.
5 citations
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May 2018 in “Drug Safety” Using electronic health records can help identify drug side effects but has some limitations.
1 citations
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September 2007 in “European journal of paediatric neurology” Low dose valproic acid treatment caused hair loss in a young patient.
14 citations
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December 2017 in “Journal of Intensive Care” Lithium poisoning can cause severe health complications and requires careful monitoring.
1 citations
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April 2009 in “Journal of Intellectual Property Law & Practice” UK courts and the European Patent Office are now more open to granting patents for new dosage regimes.
14 citations
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June 1952 in “The BMJ” Phenobarbitone can cause severe and sometimes fatal skin reactions.
13 citations
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September 1989 in “International Journal of Dermatology” Carbamazepine may cause reversible nail detachment.
April 2026 in “Journal of Cancer” Cepharanthine shows promise as a natural anticancer treatment.
March 2023 in “Epilepsia” Trilostane may help delay epilepsy development by increasing certain brain chemicals.
January 2024 in “Indonesian Journal of Pharmaceutical Education” The Caffein Herbasome® cream is stable and suitable for skin use.
17 citations
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April 2016 in “Journal of Investigative Dermatology” KB2115 (eprotirome) can safely extend the hair growth phase without damaging cells or changing hair color.
August 2023 in “Journal of The American Academy of Dermatology” Valproic acid, a common antiepileptic medication, can cause reversible hair loss in patients.
23 citations
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July 2003 in “Pharmacology, Biochemistry and Behavior” Finasteride blocks progesterone's effect on absence seizures in rats.
14 citations
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August 2021 in “Molecular Genetics and Metabolism Reports” Pegvaliase effectively reduces blood phenylalanine levels in most PKU patients, but requires personalized plans and good communication to manage side effects.
July 2015 in “Reactions weekly” Lamotrigine can cause hair loss in some patients.
8 citations
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July 2023 in “Frontiers in Pharmacology” Cepharanthine shows promise as a COVID-19 treatment.
6 citations
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June 2013 in “Toxicological Research” Topical Valproate is safe for human skin and unlikely to cause irritation.