research Directed Expression of a Chimeric Type II Keratin Partially Rescues Keratin 5-null Mice
A chimeric keratin partially improved skin structure in mice lacking keratin 5, but didn't fully restore normal skin.
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150-180 / 1000+ resultsresearch ANTI‐HAIR KERATIN MONOCLONAL ANTIBODY (HKN‐2)
HKN-2 antibody targets specific skin and hair cells, showing keratin complexity.
research Self-consistent field theory for the interactions between keratin intermediate filaments
Keratin filaments' elasticity is influenced by their terminal domains and surrounding medium.
research Alterations in the expression of specific epidermal keratin markers in the hairless mouse by the topical application of the tumor promoters 2,3,7,8-tetrachlorodibenzo-p-dioxin and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate
TCDD changes skin cell growth and keratin production in mice.
research Proteopedia entry: Coiled‐coil structure of keratins
Keratins are crucial proteins for hair and nails, with a structure that helps teach protein principles.
research Clinicopathological features and expression of four keratins (K10, K14, K17 and K19) in six cases of eruptive vellus hair cysts
Eruptive vellus hair cysts likely originate from the infrainfundibulum and sebaceous duct.
research Anti‐keratin Monoclonal Antibody against Basal Cell Epithelioma Keratin: BKN‐1
BKN-1 antibody targets specific keratin in basal cell epithelioma and normal skin basal cells.
research Biochemical examination of fetal skin biopsy specimens obtained by fetoscopy: Use of the method for analysis of keratins and filaggrin
Fetal skin biopsy can help diagnose protein-related disorders before birth.
research Synthesis and cross-linking in the structure and growth of hair keratins
The molecular details of hair growth are not well understood.
research Purification of Porcine Hair Keratin Subunits and Their Immobilization for Use as Cell Culture Substrates
Type II porcine hair keratin supports cell growth but hinders cell differentiation.
research Mouse hair keratin cDNA: Implications and sequences
Scientists identified and cloned specific keratin proteins in mouse hair.
research Acidic and basic hair/nail ("hard") keratins: their colocalization in upper cortical and cuticle cells of the human hair follicle and their relationship to "soft" keratins.
Hair and nail cells share similar proteins, indicating a common differentiation pathway.
research A family of type I keratin genes and the homeobox-2 gene complex are closely linked to the rex locus on mouse chromosome 11
Type I keratin genes are closely linked to the rex locus on mouse chromosome 11, affecting hair development.
research Two-dimensional electrophoretic analysis of human hair keratins, especially hair matrix proteins
The method effectively analyzes human hair proteins, especially nonfilamentous ones.
research Differential expression of keratin 19 in normal human epithelial tissues revealed by monospecific monoclonal antibodies
research An Ultra-high Sulfur Keratin Gene is Expressed Specifically During Hair Growth
research The complement of native α-keratin polypeptides of hair-forming cells: A subset of eight polypeptides that differ from epithelial cytokeratins
research Concerted gene duplications in the two keratin gene families
research Cloning and Characterization of a Mouse Type I Hair Keratin cDNA
research Skin tumors with matrical differentiation: lessons from hair keratins, beta‐catenin and PHLDA ‐1 expression
Matrical tumors share a common growth mechanism involving the Wnt pathway and consistent PHLDA1 expression.
research Cell Differentiation in Human Anagen Hair and Hair Follicles Studied with Anti-Hair Keratin Monoclonal Antibodies
research Solitary Nodular Lesion Over Face
A rare, benign facial tumor called fibrofolliculoma was successfully treated with surgery.
research Bacteria and fungi on the surface and within noninflamed hair follicles of skin biopsy specimens from horses with healthy skin or inflammatory dermatoses
Horses with skin disease have more surface bacteria than healthy horses.
research An Update on Pathological Changes in Canine Demodicosis
Canine demodicosis causes skin issues, anemia, and mineral deficiencies in dogs.
research Molecular modeling of hair keratin/peptide complex: Using MM‐PBSA calculations to describe experimental binding results
Electrostatic interactions mainly stabilize the binding of peptides to hair keratin.
research The human hair: from anatomy to physiology
The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.
research Human epithelial hair follicle stem cells and their progeny: Current state of knowledge, the widening gap in translational research and future challenges
We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
research Beyond Expectations
Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
research Label Retaining Cells (LRCs) with Myoepithelial Characteristic from the Proximal Acinar Region Define Stem Cells in the Sweat Gland
Sweat gland stem cells help maintain glands, aid wound healing, and can regenerate skin structures.
research Rippled‐pattern trichomatricoma
A unique hair tumor with a rippled pattern was identified, showing incomplete differentiation and unusual cell arrangements.