3 citations
,
December 2013 in “Journal of Cell Science” Keratin 79 cells help form and regenerate hair canals.
November 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Keratin 79 cells help form and regenerate hair canals.
441 citations
,
May 1996 in “Journal of Cell Science” Keratin 19 helps identify skin stem cells, with its presence varying by body location, age, and culture stage.
419 citations
,
March 2005 in “Proceedings of the National Academy of Sciences” Hair-follicle stem cells can become neurons.
356 citations
,
December 1986 in “The journal of cell biology/The Journal of cell biology” Hair and nail cells share similar proteins, indicating a common differentiation pathway.
85 citations
,
September 2013 in “International Journal of Molecular Sciences” Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.
387 citations
,
November 2003 in “Journal of Investigative Dermatology” The K15 promoter effectively targets stem cells in the hair follicle bulge.
79 citations
,
August 1998 in “The Journal of Cell Biology” Keratin 16 delays skin maturation and affects skin and hair development in mice.
52 citations
,
October 2007 in “Molecular Therapy” Injecting lentiviral vectors into early gestation mice effectively targets skin stem cells for potential gene therapy.
25 citations
,
August 2020 in “Experimental eye research/Experimental Eye Research” Different types of cells in the eye express specific keratins at various stages of development.
20 citations
,
January 1995 in “Cells tissues organs” Changing light periods synchronized wool growth cycles in sheep.
13 citations
,
July 1994 in “PubMed” Keratins K6 and K16 are expressed more freely in regenerating mouse skin than K1 and K10.
10 citations
,
January 2010 in “International journal of trichology” Keratin-associated proteins are part of the developing hair fiber cuticle.
3 citations
,
July 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Keratin 17 is important for skin's response to radiation, affecting many genes and cell division.
Human hair keratins can self-assemble and support cell growth, useful for biomedical applications.
January 2016 in “Frontiers in Bioengineering and Biotechnology” A wool hair keratin hydrogel is promising for growing cells and tissue engineering.
January 1990 in “The Nishinihon Journal of Dermatology” Follicular structures help differentiate keratoacanthoma from squamous cell carcinoma.
29 citations
,
July 1991 in “Biochimica et Biophysica Acta (BBA) - General Subjects” Glycoproteins are present in the cell membranes of various keratin fibers.
438 citations
,
October 2010 in “Oncogene” Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.
28 citations
,
June 2012 in “International Journal of Molecular Medicine” Radiation damages hair stem cells and changes keratin expression, with Krt5 as a potential marker for radiation effects.
42 citations
,
July 2010 in “European Journal of Cell Biology” Thyroid hormones affect hair follicle stem cells by promoting differentiation and reducing growth.
13 citations
,
December 2019 in “Nutrients” An apple-based supplement was found to stimulate hair protein production, which may help with hair growth.
1 citations
,
November 2012 in “European Journal of Cell Biology” The authors clarified data overlap and corrected a figure error, apologizing for any confusion.
December 2025 in “American Journal of Dermatopathology” Keratin 19 may help diagnose and treat certain types of permanent hair loss.
February 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” Keratin 15 helps keep skin cells in a young, undifferentiated state.
87 citations
,
November 2002 in “Journal of Investigative Dermatology” 58 citations
,
July 2005 in “Molecular and Cellular Biology” A specific gene segment can make mouse skin cells glow, helping study hair growth and gene effects.
2 citations
,
January 2011 in “Dental Medicine Research” Keratin 75 might be important in oral cancer progression.
24 citations
,
April 2017 in “Oncology Reports” The hair keratin gene KRT81 is found in both normal and breast cancer cells and helps them invade surrounding tissues.
18 citations
,
September 2003 in “International Journal of Cancer” EBV infection increases a specific keratin variant in carcinoma cells, possibly affecting cell structure and cancer progression.