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research Novel Type I Hair Keratins K39 and K40 Are the Last to be Expressed in Differentiation of the Hair: Completion of the Human Hair Keratin Catalog

70 citations , February 2007 in “Journal of Investigative Dermatology”

K39 and K40 are the last keratins expressed in hair development, completing the hair keratin catalog.

research Identification and sequence analysis of the keratin-associated protein 24‐1 (KAP24-1) gene homologue in sheep

51 citations , September 2012 in “Gene”

The research identified a gene in sheep important for wool quality, which could help improve wool traits.

research Crosstalk between vimentin and keratins in viral infection: Implications across the viral life cycle

March 2026 in “Virulence”

Vimentin and keratin help viruses spread and could be targets for antiviral treatments.

research The molecular basis of human keratin disorders

79 citations , February 2009 in “Human Genetics”

research Mutations in the hair cortex keratin hHb6 cause the inherited hair disease monilethrix

175 citations , August 1997 in “Nature Genetics”

research Ovine KRTAP36-2: A New Keratin-Associated Protein Gene Related to Variation in Wool Yield

November 2023 in “Genes”

The KRTAP36-2 gene in sheep affects wool yield.

research Identification of reptilian genes encoding hair keratin-like proteins suggests a new scenario for the evolutionary origin of hair

115 citations , November 2008 in “Proceedings of the National Academy of Sciences”

Reptiles have genes similar to hair proteins, suggesting hair's genetic origins predate mammals.

research Transcription Regulation and Protein Subcellular Localization of the Truncated Basic Hair Keratin hHb1-ΔN in Human Breast Cancer Cells

8 citations , June 2001 in “Journal of Biological Chemistry”

A truncated protein linked to breast cancer may change cell adhesion.

research Clinically relevant aberrant Filip1l DNA methylation detected in a murine model of cutaneous squamous cell carcinoma

7 citations , May 2021 in “EBioMedicine”

Increased methylation of the Filip1l gene may contribute to aggressive skin cancer.

research MOESM1 of A missense variant in the coil1A domain of the keratin 25 gene is associated with the dominant curly hair coat trait (Crd) in horse

January 2017

research Activated Kras Alters Epidermal Homeostasis of Mouse Skin, Resulting in Redundant Skin and Defective Hair Cycling

29 citations , October 2010 in “Journal of Investigative Dermatology”

Activating Kras in mouse skin causes excess skin and hair loss.

research The Autoimmune Regulator (AIRE), Which Is Defective in Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Patients, Is Expressed in Human Epidermal and Follicular Keratinocytes and Associates With the Intermediate Filament Protein Cytokeratin 17

24 citations , February 2011 in “The American journal of pathology”

AIRE protein, defective in APECED patients, is found in skin and hair cells and interacts with cytokeratin 17.

research A Mosaic Hotspot PLCD1 Variant, Detectable in Blood‐Derived DNA, Associated With Nevus Trichilemmocysticus

March 2025 in “American Journal of Medical Genetics Part A”

A rare genetic variant linked to skin cysts was found in blood DNA, suggesting its role in cyst formation.

research Histological study of the effect of bone marrow-derived mesenchymal stem cells on healing of skin defect in adult male albino rats

2 citations , March 2014 in “The Egyptian Journal of Histology”

Bone marrow-derived stem cells greatly improve skin wound healing in rats.

research An Autosomal Recessive Form of Monilethrix Is Caused by Mutations in DSG4: Clinical Overlap with Localized Autosomal Recessive Hypotrichosis

97 citations , March 2006 in “Journal of Investigative Dermatology”

Mutations in the DSG4 gene cause a severe form of brittle hair and skin issues.

research Proteome Analysis of Human Hair Shaft

122 citations , January 2006 in “Molecular & Cellular Proteomics”

Human hair contains many proteins, with some being highly abundant and modified.

research Delayed epidermal permeability barrier formation and hair follicle aberrations in Inv-Cldn6 mice

63 citations , April 2005 in “Mechanisms of development”

Mice with too much Claudin-6 have skin barrier problems and abnormal hair growth.

research Disorders of Keratinization

44 citations , January 2004 in “American journal of clinical dermatology”

Understanding genetic mutations helps diagnose and treat skin disorders like ichthyosis.

research A Productive Black Facial Pore

4 citations , June 1989 in “Archives of Dermatology”

A man had a black pore on his cheek, which was removed and found to be a hair follicle tumor.

research A productive black facial pore. Trichofolliculoma

2 citations , June 1989 in “Archives of Dermatology”

A black pore on a man's cheek was a hair follicle tumor and was removed.

research Merkel cell differentiation in trichoblastoma

34 citations , January 1998 in “Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin”

Trichoblastomas may mimic fetal skin development by having many Merkel cells, unlike adult skin.

research The Parathyroid Hormone Second Receptor PTH2R and its Ligand Tuberoinfundibular Peptide of 39 Residues TIP39 Regulate Intracellular Calcium and Influence Keratinocyte Differentiation

24 citations , March 2016 in “Journal of Investigative Dermatology”

TIP39 and PTH2R help control calcium levels and skin cell development.

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