1 citations
,
June 2014 in “[Thesis]. Manchester, UK: The University of Manchester; 2014.” Chemical modifications can alter hair's stability and flexibility, with hydrophobic interactions helping maintain structure in humid conditions.
180 citations
,
April 2002 in “Cell Death and Differentiation” 159 citations
,
October 1986 in “The Histochemical Journal” 93 citations
,
July 2006 in “Journal of Investigative Dermatology” K25, K27, and K28 are found in all inner root sheath layers of hair, while K26 is only in the cuticle.
92 citations
,
January 2012 in “International Journal of Biological Sciences” The document introduced a new naming system for keratin-associated proteins to improve clarity and communication across species.
76 citations
,
February 1993 in “Journal of Biological Chemistry” KAP6 genes are conserved across species and active in hair follicles.
70 citations
,
February 2007 in “Journal of Investigative Dermatology” K39 and K40 are the last keratins expressed in hair development, completing the hair keratin catalog.
65 citations
,
February 1992 in “Development” Type II keratin genes are crucial for hair follicle differentiation and have a conserved structure and expression pattern.
56 citations
,
January 1977 50 citations
,
April 2019 in “Journal of Biosciences” 47 citations
,
July 2005 in “European Journal of Cell Biology” Terrestrial vertebrates have balanced keratin gene clusters, unlike teleost fish.
47 citations
,
July 1998 in “Journal of Investigative Dermatology” A new mutation, Glu402Lys, in hair keratin is linked to variable symptoms of monilethrix.
47 citations
,
June 1994 in “Experimental Cell Research” mHa2 and mHa3 keratins have different structures and roles in mouse hair and tongue tissues.
46 citations
,
June 2013 in “Journal of structural biology” High glycine–tyrosine keratin-associated proteins help make hair strong and maintain its shape.
43 citations
,
August 1994 in “Journal of Investigative Dermatology” 41 citations
,
January 2001 in “Journal of Investigative Dermatology” 40 citations
,
December 2010 in “Human Genetics” 38 citations
,
February 1989 in “Journal of Investigative Dermatology”
32 citations
,
February 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.
31 citations
,
March 1995 in “Journal of Investigative Dermatology” 29 citations
,
July 2015 in “Journal of Medical Genetics” A genetic variant in the KRT25 gene causes tightly curled hair.
27 citations
,
November 1991 in “Journal of Investigative Dermatology” 26 citations
,
May 2001 in “British Journal of Dermatology” Pilomatrixomas likely originate from the hair matrix due to changes in hair keratin expression.
21 citations
,
January 2018 in “PLoS Genetics” Certain genetic variants in keratins increase the risk of tooth decay.
20 citations
,
October 1995 in “Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression” hHb1, hHb3, and hHb6 mRNAs start expressing at the same time in hair follicles.
18 citations
,
February 1992 in “Molecular Biology Reports” A specific type II hair keratin was identified and found in hair cortex and tongue cells.
15 citations
,
January 1991 in “Mammalian Genome” 14 citations
,
December 1998 in “British Journal of Cancer” Truncated hHb1 keratin may play a role in breast cancer cell transformation.
14 citations
,
January 1977 in “PubMed” The hair keratin variant is mostly found in Caucasians.
13 citations
,
January 2018 in “Advances in experimental medicine and biology”