52 citations
,
May 2006 in “Journal of Structural Biology” Keratin-associated proteins help link filaments and affect keratin's strength.
52 citations
,
February 1986 in “Journal of Histochemistry & Cytochemistry” Some hair proteins are specific to hair, while others are also found in skin cells.
42 citations
,
October 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Mutations in the KRT85 gene cause hair and nail problems.
41 citations
,
July 2020 in “Colloids and surfaces. B, Biointerfaces” Different hair protein amounts change the strength of keratin/chitosan gels, useful for making predictable tissue engineering materials.
41 citations
,
May 2012 in “Advanced Healthcare Materials” Human hair keratins improve cell adhesion and growth on culture surfaces.
38 citations
,
October 2011 in “Analytical biochemistry” Hair proteins have weak spots in their α-helical segments.
36 citations
,
July 2019 in “Journal of Materials Science Materials in Medicine” Human hair keratin helps repair nerve damage in rats.
34 citations
,
November 1998 in “Journal of Investigative Dermatology” A common mutation in the hHb6 gene is linked to monilethrix, but other factors may also play a role.
30 citations
,
January 1999 in “Journal of Cutaneous Pathology” Spiny keratoderma may be ectopic hair formation on palms and soles.
29 citations
,
August 1999 in “Journal of Investigative Dermatology” New mutations in hair keratin genes cause the rare hair disorder monilethrix.
24 citations
,
April 2017 in “Oncology Reports” The hair keratin gene KRT81 is found in both normal and breast cancer cells and helps them invade surrounding tissues.
23 citations
,
January 2015 in “Stem cells international” Coating surfaces with human hair keratin improves the growth and consistency of important stem cells for medical use.
19 citations
,
December 2006 in “Journal of Structural Biology” Type I and Type II keratin chains can form heterodimers despite sequence differences.
18 citations
,
October 2018 in “Nutrients” Annurca apple extract promotes hair growth by changing hair follicle metabolism to boost keratin production.
13 citations
,
August 1985 in “The Journal of Dermatology” HKN-2 antibody targets specific skin and hair cells, showing keratin complexity.
12 citations
,
January 1934 in “Proceedings of the Royal Society of London Series B Containing Papers of a Biological Character” Stretched hair has a similar structure to natural silk, showing hair's elasticity involves reversible changes within its molecules.
12 citations
,
October 2007 in “PubMed” Keratin helps protect and strengthen hair, reducing damage and color fading.
11 citations
,
September 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” A mutation in the KRT71 gene causes a hair disorder by disrupting hair follicle structure and texture.
7 citations
,
September 2020 in “International Journal of Cosmetic Science” Different sizes of keratin peptides can strengthen hair, with smaller ones possibly increasing volume and larger ones repairing damage.
7 citations
,
December 2020 in “ACS biomaterials science & engineering” Human hair keratins can form stable nanofiber networks that might help in tissue regeneration.
5 citations
,
December 2020 in “International journal of biological macromolecules” Treatments improved hair surface and scale structure but didn't increase certain bonds in the hair cortex.
5 citations
,
February 2007 in “Cytology and genetics” Gene expression regulates keratin production for normal hair growth.
5 citations
,
October 2002 in “PubMed” Human hair keratin scaffolds help repair injured muscles by breaking down and activating muscle cell growth.
5 citations
,
February 1998 in “Polymer” Human hair keratin has a 40% α-helix structure that changes to a random coil in 8 M urea.
5 citations
,
December 1996 in “Biochemical and Biophysical Research Communications” Mouse hair keratins mHa1 and mHb4 can't form a strong network on their own in cells.
3 citations
,
December 2021 in “Materials today communications” A new film made from human hair supports skin cell growth better than collagen.
3 citations
,
January 2015 in “Sen i Gakkaishi” The new keratin film without KAPs stains better and could help study keratin functions.
3 citations
,
September 2013 in “Bioscience Biotechnology and Biochemistry” Type II porcine hair keratin supports cell growth but hinders cell differentiation.
3 citations
,
May 2012 in “Journal of Biological Macromolecules” Keratin film can effectively mimic human hair for testing hair damage.
3 citations
,
March 2009 in “Hirosaki University Repository for Academic Resources (Hirosaki University)” Hirosaki hairless rats have sparse, twisted hair due to missing hair keratin genes.