314 citations
,
April 2010 in “Developmental Cell” β-catenin in the dermal papilla is crucial for normal hair growth and repair.
4 citations
,
November 1968 in “Textile research journal” Hair fibers may have a unique, non-protein sheath not previously identified.
2 citations
,
February 2021 in “FEBS open bio” Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.
February 2020 in “Definitions” Mutations in the KRT16 gene can cause skin and nail disorders.
17 citations
,
August 2018 in “BMC Genomics” The HOXC13 gene affects different hair proteins in cashmere goats in varied ways and is controlled by a feedback loop and other factors.
16 citations
,
November 2022 in “eLife” Both gene and non-gene areas of DNA evolved to make some mammals hairless.
2 citations
,
December 2022 in “International journal of molecular sciences” Plucked hairs can be used instead of skin biopsies to study hair traits because they contain specific cells related to hair.
1 citations
,
February 2023 in “All Life” The research identified proteins that change as goat hair follicles begin to form, helping to understand how cashmere grows.
122 citations
,
January 2006 in “Molecular & Cellular Proteomics” Human hair contains many proteins, with some being highly abundant and modified.
109 citations
,
September 2011 in “Human molecular genetics online/Human molecular genetics” New treatments targeting specific genes show promise for treating keratin disorders.
November 2023 in “Advanced Science” A specific hair protein variant increases the spread of breast cancer and is linked to worse survival rates.
18 citations
,
February 2006 in “Genomics” A new genetic mutation in mice causes permanent hair loss and skin wrinkling.
February 2026 in “International Journal of Molecular Sciences” PDLLA filler can improve hair thickness and shine by reducing age-related hair decline.
9 citations
,
February 2001 in “Journal of Dermatological Science” p21waf1/cip1 and p27kip1 help in hair follicle differentiation in rats.
24 citations
,
April 2017 in “Oncology Reports” The hair keratin gene KRT81 is found in both normal and breast cancer cells and helps them invade surrounding tissues.
438 citations
,
October 2010 in “Oncogene” Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.
28 citations
,
December 1997 in “Journal of Biological Chemistry” A genetic mutation in the hHa1 gene creates a smaller, but still functional, hair protein without causing hair problems.
1 citations
,
January 2021 in “Springer Proceedings in Materials” Researchers developed a new method to clearly see and label hair proteins with minimal errors using advanced freezing and microscopy techniques.
30 citations
,
December 2014 in “BMC Genetics” Certain genes and proteins may influence wool growth in Aohan fine wool sheep.
29 citations
,
August 2011 in “PubMed” Polymeric pretreatments can significantly reduce hair breakage and damage from hot flat irons.
April 2018 in “Journal of Investigative Dermatology” The keratin network in mouse skin changes during cornification and affects the skin's protective barrier.
3 citations
,
June 2020 in “Developmental Cell” Feather patterns are influenced by enhancers and chromatin looping, and the structure of protein complexes important for hair growth has been detailed.
3 citations
,
June 2017 in “Journal of Biomaterials Applications” Keratin extract from human hair was found to promote hair growth in mice.
292 citations
,
October 1985 in “The Journal of Cell Biology” Keratins and filaggrin change as fetal skin develops, marking key stages of skin formation.
517 citations
,
February 2010 in “Materials” Keratin from hair and wool is used in medical materials for healing and drug delivery.
5 citations
,
January 2017 in “Molecular Medicine Reports” Human hair follicle cells can be turned into neural stem cell-like cells, which might help treat brain diseases.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
53 citations
,
July 2009 in “Cancer Research” Blocking certain proteins can reduce skin inflammation caused by cancer treatment.
4 citations
,
January 2021 in “Skin appendage disorders” Hair straightening can damage hair and pose health risks, including exposure to carcinogens and hair loss.