November 2020 in “Research Square (Research Square)” Keratin injections in mice can stimulate hair growth and might help treat hair loss.
19 citations
,
July 1994 in “Journal of Dermatological Science” Human hair keratin genes are similar to mouse genes and are specifically expressed in hair follicles.
54 citations
,
January 2018 in “Scientific reports” Human hair contains diverse proteins, including keratins and histones, which could help assess hair health and aging.
147 citations
,
November 2020 in “International Journal of Molecular Sciences” Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
113 citations
,
December 2000 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” KGF and activin are crucial for skin healing and repair.
53 citations
,
September 1999 in “The journal of cell biology/The Journal of cell biology” K16 can partially replace K14 but causes hair loss and skin issues.
22 citations
,
June 2008 in “Experimental Dermatology” Heparanase is essential for hair follicle health and inner root sheath differentiation.
December 2023 in “ACS Sustainable Chemistry & Engineering” Keratin can be successfully taken from human hair using a mix of choline chloride and ethanolamine.
64 citations
,
April 1992 in “Differentiation” Sciellin is a protein that helps form protective layers in skin, hair, and nails.
28 citations
,
March 1993 in “Journal of Cell Science” Keratins K4 and K13 form stable dimers in mature esophageal cells, aiding cell stability.
24 citations
,
July 2014 in “Journal of Investigative Dermatology” Nagashima-type palmoplantar keratosis in Asians is caused by a SERPINB7 gene mutation.
April 2023 in “Journal of Investigative Dermatology” Blocking casein kinase 1 in skin cells can help melanocyte precursors move better, potentially helping with conditions like vitiligo or gray hair.
33 citations
,
August 2014 in “Veterinary Dermatology” Keratinocytes play a key role in skin health, but more research is needed.
January 1991 in “Acta Dermato Venereologica” A new method effectively visualizes keratin in hair without harsh chemicals.
70 citations
,
February 2007 in “Journal of Investigative Dermatology” K39 and K40 are the last keratins expressed in hair development, completing the hair keratin catalog.
3 citations
,
September 2005 in “Experimental dermatology” The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.
73 citations
,
January 2016 in “International review of cell and molecular biology” Cornification evolved from keratinization in vertebrates, with differences between mammals and sauropsids.
44 citations
,
May 1997 in “Journal of Biological Chemistry” The human keratin 6a gene's specific sequences trigger expression in skin layers after injury.
22 citations
,
July 1998 in “Journal of Investigative Dermatology” The 4C32 gene may help in mouse skin development and differentiation.
April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” CTCF protein is essential for skin and hair follicle development in mice.
86 citations
,
April 2009 in “Journal of anatomy” Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.
45 citations
,
March 1997 in “Journal of Investigative Dermatology” 45 citations
,
March 2001 in “Journal of Investigative Dermatology” A new protein, mK6irs, is found in specific hair layers and may help understand hair growth and diseases.
1 citations
,
January 2016 in “Frontiers in Bioengineering and Biotechnology” Human hair keratin is a promising and sustainable biomaterial for tissue regeneration.
79 citations
,
October 1998 in “Genomics” Mouse keratin 6 genes evolved independently from human ones and are regulated differently.
57 citations
,
August 2002 in “American Journal Of Pathology” Cathepsin L deficiency causes hair and skin issues in mice.
122 citations
,
June 2002 in “Genes & Development” Keratin 17 is crucial for early hair strength and cell survival.
1 citations
,
January 2006 High temperatures and cosmetic processes can damage hair keratin, affecting its structure and strength.
161 citations
,
June 1993 in “Journal of Biological Chemistry” Trichohyalin helps in hair and skin cell structure and function by binding calcium and linking proteins.
43 citations
,
October 2006 in “Journal of Cell Science” Keratin 10 end domains may increase skin cancer risk by reducing cell death.