research Keratin gene mutations in disorders of human skin and its appendages
Keratin gene mutations cause various skin and hair disorders, but new research offers hope for future treatments.
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390-420 / 1000+ resultsresearch remarks on the evolution of the integumental scale armour
Pangolin scales evolved for protection, hardening with age, due to keratin gene diversification.
research Autophagy-Mediated Cellular Remodeling during Terminal Differentiation of Keratinocytes in the Epidermis and Skin Appendages
Autophagy is essential for proper skin cell development and function.
research Directed Expression of a Chimeric Type II Keratin Partially Rescues Keratin 5-null Mice
A chimeric keratin partially improved skin structure in mice lacking keratin 5, but didn't fully restore normal skin.
research Importance of Citrullination on Hair Protein Molecular Assembly During Trichocytic Differentiation
research Keratin 17 Gene Expression during the Murine Hair Cycle
research Different keratin polypeptides in epidermis and other epithelia of human skin: a specific cytokeratin of molecular weight 46,000 in epithelia of the pilosebaceous tract and basal cell epitheliomas.
Basal-cell epitheliomas and the pilosebaceous tract share a unique keratin, distinguishing them from other skin areas.
research The Catalog of Human Hair Keratins
Human hair is made up of different keratins, some strong and some weak, with specific types appearing at various stages of hair growth.
research Expression patterns of hair and epithelial keratins and transcription factors HOXC13, LEF1, and β‐catenin in a malignant pilomatricoma: a histological and immunohistochemical study
The malignant pilomatricoma showed strong epithelial keratin expression, suggesting it may not calcify.
research Characterization of the Human Hair Shaft Cuticle–Specific Keratin-Associated Protein 10 Family
KRTAP10 proteins help form the hair shaft's tough outer layer by interacting with specific hair keratins.
research The toughening transition in hair keratin
The observed "toughening" in keratin was actually due to water evaporation, not a real change in keratin.
research Deciphering a Message from the Nucleus: How Transcription Factors and Spatial Chromatin Interactions Orchestrate Epidermal Differentiation
Key skin cell regulators and gene organization changes are crucial for skin cell development and could help treat skin disorders.
research Keratin expression in basal cell carcinomas
Basal cell carcinomas likely originate from hair follicle cells or stem cells.
research Self-Assembly of Solubilized Human Hair Keratins
Human hair keratins can form stable nanofiber networks that might help in tissue regeneration.
research Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled
Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.
research Adverse effects of isotretinoin: A retrospective review of 1743 patients started on isotretinoin
Most people on isotretinoin had chapped lips, but only a few stopped the medicine due to side effects.
research Growth factors and cytokines in hair follicle development and cycling: recent insights from animal models and the potentials for clinical therapy
Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.
research Biology and Genetics of Hair
The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
research Dermatologic Manifestations of Polycystic Ovary Syndrome
Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.
research Mutations in the Desmoglein 4 Gene Are Associated with Monilethrix-like Congenital Hypotrichosis
Mutations in the DSG4 gene can cause a rare hair disorder similar to monilethrix.
research Pediatric Tinea Capitis
Children with scalp fungal infections need proper diagnosis and treatment, usually with antifungal medications, and newer drugs may offer quicker recovery.
research The genetics of hair shaft disorders
The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
research Strategic Targets in Acne: The Comedone Switch in Question
The best way to treat acne is to prevent healthy skin glands from turning into acne lesions by controlling the triggers early on.
research A discourse on human hair fibers and reflections on the conservation of drug molecules
Hair analysis for drugs needs a better understanding of how drugs enter hair, considering factors like hair structure and pigmentation.
research Hormonal treatment of acne vulgaris: an update
Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.
research Influence of substance-P on cultured sebocytes
Substance P may worsen acne by increasing inflammation, but corticosteroids might help by reducing this effect.
research Acneiform Dermatoses
Some skin conditions look like acne but are caused by drugs, and they usually get better when the drug is stopped.
research Acquired scalp alopecia. Part I: A review
Accurate diagnosis is key for treating different kinds of hair loss, and immune response variations may affect the condition and treatment results.
research Skin diseases associated with atopic dermatitis
People with atopic dermatitis are more likely to develop other skin conditions due to shared genetics and immune pathways.
research A splice variant in KRT71 is associated with curly coat phenotype of Selkirk Rex cats
A gene variant in KRT71 causes the curly fur in Selkirk Rex cats.