6 citations
,
June 2024 in “Drug Testing and Analysis” Nails are being explored as an alternative to hair for evaluating long-term drug use, but differences in structure, growth, and drug incorporation between nails and hair can complicate analysis and interpretation. This review compiles literature comparing drug concentrations in hair, fingernails, and toenails, emphasizing studies with paired samples from the same individuals. While some drugs show clear results, more standardized studies are necessary to fully understand drug incorporation in nails and establish reliable cut-offs.
December 2023 in “Royal Society of Chemistry eBooks” Nails are a useful alternative to hair for analyzing long-term substance exposure.
13 citations
,
December 1991 in “Annals of the New York Academy of Sciences” Researchers created a lab model to study human hair growth, showing it can grow and self-regulate outside the body.
1 citations
,
January 2019 in “Elsevier eBooks” Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.
57 citations
,
February 2013 in “Journal of Dermatological Science” Improving the environment and cell interactions is key for creating human hair in the lab.
November 2025 in “Molecules” Microextraction techniques improve hormone testing while being environmentally friendly.
January 2023 in “Advances in pharmacology and clinical trials” Human hair is a significant sample for various tests in clinical, nutritional, archaeological, and forensic studies.
September 2025 in “International Journal of Molecular Sciences” Hair analysis could help diagnose and treat schizophrenia more effectively.
Hair and nails can show hormone changes during puberty in dogs.
48 citations
,
December 2022 in “Biomolecules” 3D bioprinting shows promise for creating advanced skin for healing wounds and reducing animal testing.
October 2023 in “Research Review” Some skin tumors from hair follicles and glands can be linked to genetic syndromes and may be benign or malignant.
23 citations
,
August 2019 in “Proceedings of the National Academy of Sciences of the United States of America” Pollution exposure speeds up hair damage.
February 2024 in “International journal of biology, pharmacy and allied sciences” Plant-based treatments can effectively and safely treat hair loss.
139 citations
,
July 1991 in “Journal of The American Academy of Dermatology” Understanding hair follicle anatomy helps diagnose hair disorders.
96 citations
,
April 2007 in “Journal of Investigative Dermatology” Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.
74 citations
,
October 1998 in “Journal of biological chemistry/The Journal of biological chemistry” The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.
47 citations
,
June 1996 in “International Journal of Legal Medicine” Hair analysis for drugs needs a better understanding of how drugs enter hair, considering factors like hair structure and pigmentation.
44 citations
,
April 2017 in “Genes & development” Scientists found cells in hair that are key for growth and color.
23 citations
,
July 1982 in “International Journal of Dermatology” The review concludes that accurate diagnosis of different types of hair loss requires proper biopsy techniques and understanding the hair growth cycle and underlying causes.
18 citations
,
November 2014 in “Journal of Agricultural and Food Chemistry” Brazilian propolis was found to speed up hair growth in mice by increasing the growth of skin cells that form hair.
10 citations
,
September 2020 in “Metabolites” Hair color and length affect metabolite profiles in hair, so they should be considered in hair analysis.
1 citations
,
January 2017 in “Springer eBooks” Hair follicles are important for drug delivery through the skin, but better methods are needed to understand and improve this process.
1 citations
,
October 2012 in “Elsevier eBooks” Skin stem cells can help improve skin repair and regeneration.
44 citations
,
December 1991 in “Annals of the New York Academy of Sciences” EGF and FGF help hair growth by affecting cell differentiation and fiber growth.
96 citations
,
September 2017 in “Analytica Chimica Acta” Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.
July 2022 in “Research Square (Research Square)” Hair analysis can somewhat track past testosterone levels but is influenced by factors like hair washing, growth rate, sex, and hair color.
252 citations
,
February 2018 in “npj Regenerative Medicine” Understanding different species' regeneration can improve mammalian healing.
205 citations
,
April 2005 in “Journal of Investigative Dermatology” Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.
126 citations
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January 1987 in “Journal of The American Academy of Dermatology” The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.
94 citations
,
September 2014 in “Therapeutic Delivery” Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.