research Characterization of the Human Hair Shaft Cuticle–Specific Keratin-Associated Protein 10 Family
KRTAP10 proteins help form the hair shaft's tough outer layer by interacting with specific hair keratins.
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780-810 / 1000+ resultsresearch Further Immunocytochemical Characterization of Cultured Hair Apparatus Cells
Immature hair cells can grow and change into different types of hair cells over time.
research Keratin-mediated hair growth and its underlying biological mechanism
Keratin injections can promote hair growth by affecting hair-forming cells and tissue development.
research Structure and function of skin, hair and nails
Understanding skin's structure and function is crucial for grasping skin health and diseases.
research Epithelial stem cells and implications for wound repair
Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.
research Fabrication of Chimeric Hair Follicles for Skin Tissue Engineering
Engineered skin with hair follicles can improve burn treatments.
research Seborrheic karatosis, a tumor of the infundibular and isthmus of hair follicles: Identification of hair sheath keratins and histopathological features suggesting hair follicle origin.
Seborrheic keratosis likely originates from the upper regions of hair follicles.
research New aspects of the structure of human hair on the basis of optical microscopic observations of disassembled hair parts.
Human hair's strength comes from a honeycomb-like structure and macrofibrils.
research Immunohistochemical staining characteristics of epidermal appendages (hair follicles and eccrine sweat glands) to anti-epidermal keratin antisera
Hair follicles and sweat glands show different keratin staining patterns.
research The molecular basis of human keratin disorders
research Transient expression of keratin 19 is induced in originally negative interfollicular epidermal cells by adhesion of suspended cells.
Keratin 19 expression in certain skin cells is temporary and not a reliable stem cell marker.
research Calcified Epidermal Cyst on the Neck
Calcified epidermal cysts are rare, hard skin nodules that are best treated with surgical removal.
research Regulation of Keratin Gene Expression in Hair Follicle Differentiationa
Keratin gene regulation is similar across mammals, affecting hair follicle differentiation.
research Expression of Basement Membrane Proteins and Interstitial Collagens in Dermal Papillae of Human Hair Follicles
research Keratins: the hair shaft's backbone revealed
Keratins are crucial for hair strength, and mutations in certain keratin genes cause hair disorders.
research Organizational principles of integumentary organs: Maximizing variations for effective adaptation
Integumentary organs adapt and evolve for survival, with potential uses in regenerative medicine.
research Demonstration of early anagen-specific stimulatory factors within skin tissue for in vitro mesenchymal-epithelial interaction in collagen embedded hair follicle mixed culture
research The Proteins of Normal and Aberrant Hair Keratins
Hair is mostly made of three protein types: helical, high-sulfur, and high-tyrosine.
research Single-Cell Proteomics Uncovers Dual Traits of Dermal Sheath Cells in Wound Repair
Dermal sheath cells help heal wounds by showing both skin and connective tissue traits.
research Defining a Region of the Human Keratin 6a Gene That Confers Inducible Expression in Stratified Epithelia of Transgenic Mice
The human keratin 6a gene's specific sequences trigger expression in skin layers after injury.
research Hair Follicle Keratins
Hair growth can be influenced by manipulating keratin and growth factor genes.
research Embryologic layers in dermatology: Developmental checkpoint disorders, diagnostic insight, and regenerative futures
Understanding embryologic layers improves skin disorder diagnosis and supports developing targeted therapies.
research Expression of the Intermediate Filament Keratin Gene,K15,in the Basal Cell Layers of Epithelia and the Hair Follicle
K15 gene is mainly active in the basal layers of hair follicles and epithelia, aiding early skin cell development.
research Understanding the Nano‐topography Changes and Cellular Influences Resulting from the Surface Adsorption of Human Hair Keratins
Human hair keratins improve cell adhesion and growth on culture surfaces.
research Dissection of a Complex Enhancer Element: Maintenance of Keratinocyte Specificity but Loss of Differentiation Specificity
Keratinocyte gene expression is controlled by multiple modules with specific binding sites.
research HPV8 Field Cancerization in a Transgenic Mouse Model Is due to Lrig1+ Keratinocyte Stem Cell Expansion
HPV8 causes skin cancer by expanding specific skin stem cells.
research The complement of native α-keratin polypeptides of hair-forming cells: A subset of eight polypeptides that differ from epithelial cytokeratins
research Epidermal cells: methods and protocols
research Immunolocalization of junctional proteins in human hairs indicates that the membrane complex stabilizes the inner root sheath while desmosomes contact the companion layer through specific keratins
Junctional proteins stabilize the inner root sheath and connect the companion layer in human hair.
research Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease
The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.