research Generation and characterization of hair-bearing skin organoids from human pluripotent stem cells
Scientists created hair-growing skin models from stem cells, which could help treat hair loss and skin diseases.
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research Structural and biochemical changes underlying a keratoderma-like phenotype in mice lacking suprabasal AP1 transcription factor function
Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.
research Experimental Modulation of the Differentiated Phenotype of Keratinocytes from Epidermis and Hair Follicle Outer Root Sheath and Matrix Cells
ORS and hair matrix cells balance growth and differentiation better than normal keratinocytes, with human dermal fibroblasts crucial for proper differentiation.
research Manipulation of stem cell proliferation and lineage commitment:visualisation of label-retaining cells in wholemounts of mouse epidermis
Stem cell behavior varies with stimuli, and lineage changes can happen without affecting stem cell division.
research The Function and Structure of the Skin
The skin protects the body, regulates temperature, senses touch, and makes vitamin D.
research Coexpression of Keratins Characteristic of Skin and Hair Differentiation in Nail Cells
research A STUDY OF THE DIFFERENTIATION PRODUCTS OF THE HAIR FOLLICLE CELLS WITH THE ELECTRON MICROSCOPE.
Hair follicle cells become four types: medulla, cortex, cuticle, and inner root sheath.
research Trichohyalin: Purification from Porcine Tongue Epithelium and Characterization of the Native Protein
Trichohyalin, a protein from pig tongue, was purified and found to have a filamentous structure.
research Hair follicle differentiation‐specific keratin expression in human basal cell carcinoma
Targeted therapies promoting differentiation could help treat basal cell carcinoma by exhausting cancer stem cells.
research Faculty Opinions recommendation of The keratins of the human beard hair medulla: the riddle in the middle.
Beard hair medulla cells have a unique and varied keratin pattern.
research KERATOSIS FOLLICULARIS WITH UNUSUAL INVOLVEMENT OF THE SCALP
A rare case of severe scalp hair loss and nail issues in keratosis follicularis was observed.
research Anti‐keratin Monoclonal Antibody against Basal Cell Epithelioma Keratin: BKN‐1
BKN-1 antibody targets specific keratin in basal cell epithelioma and normal skin basal cells.
research Inherited ichthyoses/generalized Mendelian disorders of cornification
Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.
research Ribonucleic Acids Coding for the Keratin Complex of Hair
Keratin proteins in hair are complex and come from multiple gene families.
research Trichohyalin-Like Proteins Have Evolutionarily Conserved Roles in the Morphogenesis of Skin Appendages
Trichohyalin-like proteins are essential for the development of skin structures like hair, nails, and feathers.
research Basal cells in the epidermis and epidermal differentiation
The exact identity of skin stem cells and how skin cells differentiate is not fully known.
research The structure and organization of lanceolate mechanosensory complexes at mouse hair follicles
Lanceolate complexes in mouse hair follicles are essential for touch and depend on specific cells for maintenance and regeneration.
research Tight junctions form a barrier in porcine hair follicles
Tight junctions create a barrier in pig hair follicles that controls what can enter the skin.
research Development and Maintenance of Epidermal Stem Cells in Skin Adnexa
Epidermal stem cells create and maintain skin structures like hair and nails through specific signaling pathways and vary by location and function.
research Histologic Changes in Seborrheic Keratoses after Rubbing
Rubbing seborrheic keratoses causes specific skin changes and may link them to hair follicles.
research Human keratin hydrogels support fibroblast attachment and proliferation in vitro
research Keratin expression in the human hair follicle
research Tooth, hair and claw: Comparing epithelial stem cell niches of ectodermal appendages
The conclusion is that teeth, hair, and claws have similar stem cell niches, which are important for growth and repair, and more research is needed on their regulation and potential markers.
research Hair keratin pattern in human hair follicles grown in vitro
Human hair follicles grown in vitro maintain normal keratin patterns and structure.
research Trichilemmal Carcinoma of the Thigh
Trichilemmal carcinoma is rare, usually benign after removal, but needs close follow-up due to recurrence risks.
research Collagen-type synthesis in human-hair papilla cells in culture
research Author response: Hair follicle epidermal stem cells define a niche for tactile sensation
Skin stem cells in hair follicles are important for touch sensation.
research Characterization of Epithelial Hair Follicle Stem Cells in Lichen Planopilaris and Folliculitis Decalvans Through Keratin 19 Expression
Keratin 19 may help diagnose and treat certain types of permanent hair loss.
research Characterization of Human KAP24.1, A Cuticular Hair Keratin-Associated Protein with Unusual Amino-Acid Composition and Repeat Structure
Scientists discovered a unique hair protein, KAP24.1, with a special structure, found only in the upper part of hair cuticles.
research Histology, lectin histochemistry and ultrastructure of interdigital gland in crossbred sheep
The interdigital gland in crossbred sheep is similar to skin and has specialized structures for secretion.