research Keratohyalin, Trichohyalin and Keratohyalin‐Trichohyalin Hybrid Granules: An Overview
Keratohyalin and trichohyalin proteins help form and organize skin and hair structures.
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420-450 / 1000+ resultsresearch Transdifferentiation of corneal epithelium: evidence for a linkage between the segregation of epidermal stem cells and the induction of hair follicles during embryogenesis.
Corneal cells can transform into hair-producing skin cells when exposed to certain signals.
research Histochemical studies on cutaneous stem cells in human fetal skin
Basal layer skin cells help form the epidermis and hair follicles.
research Keratin expression in basal cell carcinomas
Basal cell carcinomas likely originate from hair follicle cells or stem cells.
research Culture of hair matrix and follicular keratinocytes
research A single type of progenitor cell maintains normal epidermis
One type of progenitor cell can maintain normal skin in mice.
research Dermal papilla cells induce keratinocyte tubulogenesis in culture Elina S. ChermnykhEkaterina A. VorotelyakKsenia Y. Gnedeva • Marianna V. MoldaverYegor E. YegorovAndrey V. Vasiliev •
Dermal papilla cells can help form hair-like structures in lab-grown skin cells.
research Retinoids and Keratinization
Retinoids can help treat skin disorders by improving the skin's outer layer.
research Establishment of a new three‐dimensional human epidermal model reconstructed from plucked hair follicle‐derived keratinocytes
A new skin model from hair follicles is a safer, simpler alternative for skin tests.
research In vitro Keratin Expression of Hair Cells
Hair cells grown in a lab showed specific hair proteins.
research Overexpression of human keratin 16 produces a distinct skin phenotype in transgenic mouse skin
High levels of human keratin 16 in mice cause skin lesions and abnormal skin development.
research Onset of Keratin 17 Expression Coincides with the Definition of Major Epithelial Lineages during Skin Development
Keratin 17 is important for skin development and may help define skin cell types.
research Differential Expression of Genes Encoding a Cysteine-Rich Keratin Family in the Hair Cuticle
research Development of a mechanically stable human hair keratin film for cell culture
A new film made from human hair supports skin cell growth better than collagen.
research P5 Assembly of hair keratins in thansfected cultured cells
research Differentiation of Mouse Induced Pluripotent Stem Cells into a Multipotent Keratinocyte Lineage
Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.
research Synthesis and cross-linking in the structure and growth of hair keratins
The molecular details of hair growth are not well understood.
research Analysis on the maintenance mechanisms of human interfollicular epidermal stem cell and their niche
Epidermal stem cells use integrin β1 and α6 as markers and CD271+ cells help maintain skin health and heal wounds.
research Spiny Keratoderma
Spiny keratoderma is a rare skin condition with small spines on palms and soles, possibly linked to abnormal hair formation.
research 560 Isolation of an “early” transit amplifying keratinocyte population in interfollicular human epidermis: a role for CD271 receptor
Scientists found a new type of skin cell that could help with skin repair and these cells work better with a certain protein.
research In vivo formation steps of the hard α-keratin intermediate filament along a hair follicle: Evidence for structural polymorphism
Hair follicles form hard α-keratin filaments in four steps, showing structural differences.
research Expression of enhancing factor/phospholipase A2 in skin results in abnormal epidermis and increased sensitivity to chemical carcinogenesis
research Trichilemmoma.Cell biology of the normal human outer root sheath.
The outer root sheath in hair follicles changes during growth, with different keratinization processes in its layers.
research Abstract 5020: Characterization of epidermal stem cells in SKH1 hairless mice, a widely used mouse model to investigate ultraviolet radiation carcinogenesis.
SKH1 hairless mice have identifiable epidermal stem cells with specific markers.
research Keratinization and its Disorders
Mutations in keratin genes can cause skin and mucosa disorders.
research The expanding significance of keratin intermediate filaments in normal and diseased epithelia
Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.
research Deriving Keratinocyte Progenitor Cells and Keratinocytes from Human‐Induced Pluripotent Stem Cells
Scientists developed a way to create skin and hair cells from human stem cells, which could help treat burns and restore hair.
research Manipulation of stem cell proliferation and lineage commitment:visualisation of label-retaining cells in wholemounts of mouse epidermis
Stem cell behavior varies with stimuli, and lineage changes can happen without affecting stem cell division.
research Rat Hair Follicle Dermal Papillae Have an Extracellular Matrix Containing Basement Membrane Components
research α-parvin is required for epidermal morphogenesis, hair follicle development and basal keratinocyte polarity
α-parvin is necessary for skin and hair growth and for the correct orientation of skin cells.