79 citations
,
June 1993 in “Molecular and Cellular Biology” The K5 promoter controls gene expression in skin cells, with specific DNA segments crucial for targeting and regulation.
5 citations
,
September 2013
28 citations
,
February 2014 in “PLoS ONE” Epidermal stem cells on a special membrane helped mice regrow full skin with hair and functions.
26 citations
,
July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.
Toxins can disrupt skin stem cell balance, causing skin overgrowth or ulceration.
1 citations
,
October 2017 in “Frontiers in Physiology” Hair follicle keratin may have been used in tooth enamel evolution.
March 2015 in “Plastic and reconstructive surgery” Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.
39 citations
,
March 2022 in “Nature Protocols” Scientists created hair-growing skin models from stem cells, which could help treat hair loss and skin diseases.
December 2012 in “Journal of Dermatological Science” Wnt/beta-catenin signaling in the skin helps fat cell development during hair growth and repair.
23 citations
,
November 2018 in “Development, Growth & Differentiation” Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.
2 citations
,
March 2018 in “Biotechnology Letters” Scientists created a new cell line from Cashmere goat hair and found that cytokeratin 13 is a unique marker for certain skin cells.
December 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” New cells join the hair's dermal papilla during the growth phase, possibly affecting hair thickness.
21 citations
,
December 2015 in “European journal of cell biology” Tight junctions create a barrier in pig hair follicles that controls what can enter the skin.
91 citations
,
March 1994 in “Journal of Investigative Dermatology”
September 2009 in “International Journal of Dermatology and Venereology” Dermal papilla cells play a key role in hair growth and health.
April 2018 in “Journal of Investigative Dermatology” Basonuclin 1 (BNC1) helps skin cells multiply and move, which is crucial for wound healing.
23 citations
,
June 2016 in “FEBS Journal” Boosting β-catenin signaling in certain skin cells can enhance hair growth.
40 citations
,
November 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Different melanocyte types in hair follicles either survive or die during the catagen phase.
159 citations
,
January 2006 in “BMC Cell Biology” Wnt signaling can improve skin healing by promoting epithelial growth.
January 2019 in “Institutional Repositories DataBase (IRDB)” Hair follicles and skin structures were successfully regenerated in the lab using specific cell arrangements and mechanical conditions.
11 citations
,
August 1995 in “Journal of Investigative Dermatology” April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Certain immune cells, when activated by specific signals, can encourage hair growth.
July 1995 in “Journal of Dermatological Science” 2 citations
,
September 2010 in “Acta Ophthalmologica” Meibomian glands are like hair follicles without a hair shaft.
40 citations
,
March 1991 in “Journal of Investigative Dermatology” 51 citations
,
January 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists discovered a unique hair protein, KAP24.1, with a special structure, found only in the upper part of hair cuticles.
64 citations
,
March 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” GPRC5D is linked to the formation of hair, nails, and certain tongue areas.
55 citations
,
March 2012 in “Journal of Investigative Dermatology” Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.
8 citations
,
April 2014 in “Clinical and Experimental Dermatology” Eruptive vellus hair cysts likely originate from the infrainfundibulum and sebaceous duct.
105 citations
,
October 2017 in “Stem cells” Wnt signaling is crucial for skin development and hair growth.