124 citations
,
December 2016 in “Pharmaceuticals” TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
105 citations
,
January 2010 in “Mediators of Inflammation” Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.
89 citations
,
May 2005 in “Stem Cells” Mouse skin has special cells in the epidermis that decrease with age and are linked to keratinocyte stem cells.
68 citations
,
June 2005 in “Expert Opinion on Therapeutic Targets” Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.
42 citations
,
October 2011 in “Seminars in Cell & Developmental Biology” Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
37 citations
,
February 2007 in “Experimental Dermatology” Increasing PDCD4 protein may help prevent or treat some skin cancers.
36 citations
,
February 2007 in “Journal of biological chemistry/The Journal of biological chemistry” The vitamin D receptor can work without its usual activating molecule.
34 citations
,
August 2018 in “Cancer research” Fixing DNA errors is crucial to prevent skin cancer.
26 citations
,
July 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
22 citations
,
December 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” A mouse gene mutation increases the risk of skin cancer.
21 citations
,
August 2007 in “Experimental Dermatology” Overexpression of hurpin in mice leads to abnormal skin and higher skin cancer risk.
12 citations
,
November 2012 in “BioMolecular Concepts” PPAR β/δ is important for skin health and disease treatment, but more research is needed.
10 citations
,
April 2009 in “Oncology Reports” Bald-headed individuals may need early non-invasive detection for skin changes linked to cancer risk.
6 citations
,
January 2018 in “Advances in experimental medicine and biology” Researchers created artificial human skin using special cells, which could help treat skin conditions like albinism and vitiligo.
5 citations
,
August 2025 in “Journal of Radiation Research” Understanding skin reactions to radiation has improved, helping to reduce injuries and prevent skin cancer.
5 citations
,
May 2020 in “Life science alliance” Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.
2 citations
,
June 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Epigenetic factors play a crucial role in skin health and disease.
1 citations
,
January 2012 in “Elsevier eBooks” The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.
December 2024 in “Journal of Investigative Dermatology” The conference highlighted new treatments and research in pediatric skin conditions, emphasizing collaboration and innovation.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing MCPIP1 from myeloid cells in mice leads to hair loss and prevents skin tumors but causes pigmented spots.
Ribonucleotide excision repair is crucial to prevent skin cancer.
Ribonucleotide excision repair is crucial to prevent skin cancer.
August 2021 in “Journal of Investigative Dermatology” Adjusting polyamine levels could help treat skin disorders like psoriasis and skin cancer.
The ketogenic diet might improve certain skin conditions, but more research is needed to confirm its effectiveness.
September 2015 in “British Journal of Dermatology” Most clinicians follow discharge guidelines, many lupus patients don't use sunscreen regularly, dithranol is effective for psoriasis, biopsy methods should be based on lesion type, voriconazole may raise skin cancer risk, a new scale can help diagnose female hair loss early, and most melanomas may develop from existing moles.
March 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” Suppressing very long chain fatty acids is linked to skin cancer.
70 citations
,
September 2008 in “PubMed” MicroRNAs are important for skin development and diseases and could be used for treatment and diagnosis.
1 citations
,
February 2020 in “The Journal of clinical investigation/The journal of clinical investigation” Certain cancer drugs interact with skin bacteria to cause acne-like rashes.
1 citations
,
June 2011 in “InTech eBooks” Darker skin provides more protection against UV damage and cancer.
51 citations
,
March 2022 in “Frontiers in Immunology” Alarmin cytokines are key in controlling skin immunity and inflammation.