13 citations
,
September 2022 in “Biomolecules” The research confirms that Hidradenitis Suppurativa is characterized by increased inflammation, disrupted skin cell organization, and abnormal metabolic processes.
13 citations
,
January 2018 in “Yonsei Medical Journal” A specific gene mutation causes Olmsted syndrome.
9 citations
,
February 2016 in “Anatomical Science International” Hair proteins change location and structure as hair cells mature.
8 citations
,
January 2023 in “International journal of molecular sciences” Transglutaminase activity is important for skin and is found in both mammals and birds.
5 citations
,
August 2025 in “Journal of Radiation Research” Understanding skin reactions to radiation has improved, helping to reduce injuries and prevent skin cancer.
4 citations
,
August 2022 in “International Journal of Molecular Sciences” Human foreskin does not show aging or reduced cell growth after radiation, and H2A.J is not a good marker for radiation-induced aging.
2 citations
,
December 2023 in “International journal of molecular sciences” Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.
1 citations
,
March 2024 in “International journal of molecular sciences” Radiation therapy damages skin structure and immune function, causing inflammation and potential hair loss.
1 citations
,
July 2023 in “Journal of developmental biology” Bird foot scales develop differently and can repair but not fully regenerate due to the lack of specialized stem cell areas.
October 2025 in “Journal of Investigative Dermatology” Iron balance is crucial for skin health, affecting conditions like psoriasis and hair loss.
1 citations
,
April 2016 in “Journal of Investigative Dermatology” Zinc deficiency causes reversible hair loss by disrupting hair growth and stem cell function.
5 citations
,
July 2023 in “Microorganisms” The study found specific skin and cell changes in patients with monkeypox, helping diagnose and understand the disease.
January 2022 in “Faculty of 1000 Research Ltd” Understanding molecular mediators can improve skin healing treatments.
201 citations
,
May 2001 in “Proceedings of the National Academy of Sciences” Overexpression of COX-2 in mice skin causes abnormal skin and hair development.
5 citations
,
September 2022 in “Antioxidants” A substance from Caulerpa racemosa seaweed may protect against skin damage caused by air pollution by reducing oxidative stress and cell death.
32 citations
,
April 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” Loss of keratin K2 causes skin problems and inflammation.
14 citations
,
October 2020 in “Scientific reports” Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.
11 citations
,
March 2004 in “Journal of Comparative Pathology” Norfolk Terriers have a genetic skin defect causing scaling and blisters due to a keratin issue.
22 citations
,
October 1996 in “Dermatologic clinics” Understanding intermediate filaments helps explain hair health and related diseases.
23 citations
,
January 2023 in “Journal of Developmental Biology” Reptile skin protects and prevents water loss, helping them adapt to land.
3 citations
,
April 2022 in “F1000Research” Understanding biological mediators in skin healing can improve treatments for skin wounds.
June 2024 in “Sohag Medical Journal” Vitamin D is linked to hair health, but more research is needed for its use in treating female hair loss.
100 citations
,
March 2006 in “Journal of biological chemistry/The Journal of biological chemistry” Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.
27 citations
,
April 2011 in “International journal of legal medicine” In situ DNA labeling in hair can help predict forensic DNA analysis success.
10 citations
,
November 2018 in “Genetics in medicine” Lack of cystatin M/E causes thin hair and dry skin.
March 1998 in “Journal of dermatological science” Protease Nexin-1 is found in human hair growth cells and is affected by male hormones.
February 2024 in “Sohag Medical Journal” Various local treatments for alopecia areata show promise, but individualized plans and more research are needed.
70 citations
,
January 2014 in “International review of cell and molecular biology” Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
65 citations
,
February 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Anti-acne medications may work by reducing the activity of a protein involved in acne development.
60 citations
,
November 2013 in “Development” Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.